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The map label for this gene is xapR [H]

Identifier: 126454064

GI number: 126454064

Start: 3977384

End: 3978283

Strand: Direct

Name: xapR [H]

Synonym: BURPS1106A_4072

Alternate gene names: 126454064

Gene position: 3977384-3978283 (Clockwise)

Preceding gene: 126453224

Following gene: 126454947

Centisome position: 99.72

GC content: 71.67

Gene sequence:

>900_bases
ATGGACCTGACTCTGCTCCGCGCGTTCGTCGCGGTCGCGCGCGAGGGCAACCTCACGCGCGCGGCGGCGCAACTGCATCT
GACGCAGCCCGCCGTCAGCCTGCAGATCAAGAATCTGCAGGATCTGCTCGGCATCGCGCTGTTCGTGCGCACGTCGCGCG
GGCTCGTGCTCACGCGCGACGGCCAGGCGCTGCTGCCGCACGCGGAACGCGCGCTCGACGCGGCGGCCGACGTGAAGCGC
GCGGCCGCCGCGCTCAGGCACGAAGTGCGCGGCAGGCTGCGGATCGGCACGATTCTCGACCCCGAGTTCCTGCGGCTGGG
CGGCTTCCTGAAGCGGCTCGTCGAAGCGCATCCGCAGATCGAGACGGCGCTGCGGCACGGCATGTCCGGCTGGGTGCTCG
ACGAGGTCCGCGCGCGCGAGCTCGACGTCGGCTATTACATCGGCCGGCCGGAGGAGGACGATCCGCGCGACGCCGAGCGC
TTTCACACGGTGACGCTCACGCAGTTCCGCTACCGGGTGCTCGCGCCCGCCGGCTGGAAGGAGCGCGTGCAGCGCGCGCG
CACGTGGCGCGAGCTCGCGGCACTGCCGTGGATCTGGACGCCCGCCGCATCCGCGCACCAGCGCCTCCTGTCGCGCCGCT
TCGCCGATGCGGGCGCGCAGCCCGTGAAGGTCGCCGAGGTCGATCAGGAGACGTCGATGCTCGATCTCGTCAAATCGGGA
GTCGGCCTGACACTCGCGCGCGATTCGATCGCGCTGCGGGAGGCGCACGCGCACGCGCTCACGATCGTCGAGCATGTCGC
GGTGCCCGCCGAGCTCACGTTCGTCACGCTCGCCGATCGCCGCGACGAACCGGCGATCGCCGCCGCGCTTCGCCTCATCG
ACGAGCAGTGGGCGATATGA

Upstream 100 bases:

>100_bases
CGCGTATCGCGCGCTTCGGGAATGAAGCGTACCCGCGGCCCCCATGCGCGATCCAATGAGTTATGCTCAATTGCGTTATA
AGCCGCGCTAATATTGCTCG

Downstream 100 bases:

>100_bases
GCGCCGCTGATGATGGTCGATACGGCGGCGGCCGGGCGTCGCGAAGCGGGGAAAAGCGGCGATGCGCGCCGGCACGACGC
GCGCGCGGGGTTCGCTCCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGIALFVRTSRGLVLTRDGQALLPHAERALDAAADVKR
AAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQIETALRHGMSGWVLDEVRARELDVGYYIGRPEEDDPRDAER
FHTVTLTQFRYRVLAPAGWKERVQRARTWRELAALPWIWTPAASAHQRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLADRRDEPAIAAALRLIDEQWAI

Sequences:

>Translated_299_residues
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGIALFVRTSRGLVLTRDGQALLPHAERALDAAADVKR
AAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQIETALRHGMSGWVLDEVRARELDVGYYIGRPEEDDPRDAER
FHTVTLTQFRYRVLAPAGWKERVQRARTWRELAALPWIWTPAASAHQRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLADRRDEPAIAAALRLIDEQWAI
>Mature_299_residues
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGIALFVRTSRGLVLTRDGQALLPHAERALDAAADVKR
AAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQIETALRHGMSGWVLDEVRARELDVGYYIGRPEEDDPRDAER
FHTVTLTQFRYRVLAPAGWKERVQRARTWRELAALPWIWTPAASAHQRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLADRRDEPAIAAALRLIDEQWAI

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=253, Percent_Identity=30.8300395256917, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787601, Length=292, Percent_Identity=24.6575342465753, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=26.4, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=36.1702127659575, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788887, Length=250, Percent_Identity=29.6, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=25.2032520325203, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994962, Length=158, Percent_Identity=32.2784810126582, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=155, Percent_Identity=32.258064516129, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=105, Percent_Identity=38.0952380952381, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789173, Length=63, Percent_Identity=52.3809523809524, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790399, Length=143, Percent_Identity=30.0699300699301, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI87081904, Length=154, Percent_Identity=35.0649350649351, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1786448, Length=182, Percent_Identity=30.2197802197802, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33292; Mature: 33292

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGIALFVRTSRGLVLTRD
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHCCCCCEEEECC
GQALLPHAERALDAAADVKRAAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQI
CCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCHH
ETALRHGMSGWVLDEVRARELDVGYYIGRPEEDDPRDAERFHTVTLTQFRYRVLAPAGWK
HHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCHHHHHEEEEHHHHHHHHCCCCCHH
ERVQRARTWRELAALPWIWTPAASAHQRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
HHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCC
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLADRRDEPAIAAALRLIDEQWAI
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLTLLRAFVAVAREGNLTRAAAQLHLTQPAVSLQIKNLQDLLGIALFVRTSRGLVLTRD
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHEEHHHHHHHHHHHHHHCCCCCEEEECC
GQALLPHAERALDAAADVKRAAAALRHEVRGRLRIGTILDPEFLRLGGFLKRLVEAHPQI
CCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCHH
ETALRHGMSGWVLDEVRARELDVGYYIGRPEEDDPRDAERFHTVTLTQFRYRVLAPAGWK
HHHHHCCCCCCHHHHHHHHHCCCCEEECCCCCCCCCHHHHHEEEEHHHHHHHHCCCCCHH
ERVQRARTWRELAALPWIWTPAASAHQRLLSRRFADAGAQPVKVAEVDQETSMLDLVKSG
HHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCC
VGLTLARDSIALREAHAHALTIVEHVAVPAELTFVTLADRRDEPAIAAALRLIDEQWAI
CCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]