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The map label for this gene is degP [H]

Identifier: 126453924

GI number: 126453924

Start: 2798898

End: 2800406

Strand: Reverse

Name: degP [H]

Synonym: BURPS1106A_2845

Alternate gene names: 126453924

Gene position: 2800406-2798898 (Counterclockwise)

Preceding gene: 126453386

Following gene: 126455078

Centisome position: 70.21

GC content: 69.45

Gene sequence:

>1509_bases
ATGATGAATCCCTCGCTGCGCACCTGGCTCGTCGCCGCGGCGGTGACGGCCTTGACGCCGCTTGCCGCGCAATCGGCGAC
GGCGGCTCCGAATGTCACGACCACGCCCGCCGCAACGGGCGCCGCGCCCGCGGCGCGCGCGGGCCTGCCCGATTTCGCGG
ACCTCGTCGAGCGGGTCGGCCCGGCGGTCGTCAACATCCGGACGACGGCGAACGTGCCGGCCGATACGCGCGGCGCGCTG
CCGCCCGGCCTCGACAACGGCGACATGTCGGAGTTCTTCCGCCGCTTCTTCGGCATTCCGTTGCCGCAGGGGCCGGGCGG
GCAGAAGAACGCGCCGAGCACGCCCGATGCGCCCGACACCGAACAGAACCGCGGCGTGGGCTCGGGCTTCATCCTGTCGC
CGGACGGCTATGTGATGACGAACGCGCACGTCGTCGACGACGCGGACACGATCTACGTGACGCTCACCGACAAGCGCGAA
TTCAAGGCAAAGCTCATCGGCGTCGACGAGCGCACGGACGTCGCGATCGTGAAGATCAACGCGTCGAGCCTGCCGACCGT
CGCGATCGGCGATTCGAACCGCGTGCGCGTCGGCGAATGGGTCGTCGCGATCGGTTCGCCGTTCGGCCTCGACAACACCG
TCACGGCCGGCATCGTCAGCGCAAAGGGCCGCAACACCGGCGACTATCTGCCGTTCATCCAGACGGACGTCGCGGTCAAC
CCCGGCAACTCGGGCGGCCCGCTCATCAACATGCAGGGCGAGGTGATCGGCATCAACTCGCAGATCTACAGCCGCACGGG
CGGCTTCATGGGCATTTCGTTCGCGATTCCGATCGACGAGGCGATGCGCGTCGCCGAGCAACTGAAGGCATCGGGCAAGG
TCACGCGCGGCCGGATCGCGGTCGCGATCGGCGAGGTGACGAAGGAAGTGGCGGATTCGATCGGCCTGCCGAAGGCCGAA
GGCGCGCTCGTCAGCAGCGTCGAGCCAGGCGGCCCGGCCGACAAGGCGGGCCTGCAGCCGGGTGACATCATCCTGAAGTT
CAACGGCCGTCCGGTGGAGGCGGCGTCGGATCTGCCGCGCATGGTCGGCGACACGAAGCCGGGCGCGAAGGCGACGGTGA
CGGTGTGGCGCAAGGGGCAATCGCGCGATCTGCCGATCACGATCGCGGAATTCCCGGCTGACAAGGCCGCGAAGGCCGAC
AGCCGTCAGGCGCCGCAGCAGAAGCCGCGCAGCAGCGCGCTCGGCCTGACGGTCAGCGACCTGTCGCCCGAGCAGTTGAA
GACGCTCAAGCTGCGCAACGGCGTGCAGATCGACGCGGTCGACGGCCCGGCCTCGCGCGCGGGGCTGCAGCGCGGCGACA
TCGTGCTGCGCGTCGGCGACGTCGACATCACGAGCGCGAAGCAGTTCGTCGACGTGACGTCGAAGCTCGATCCGCAGCGC
GCGGTCGCGGTGCTCGTGCGGCGCGGCGAGAACACGCAGTTCATCCCGATCCGGCCGCGTCAGAAGTGA

Upstream 100 bases:

>100_bases
TTCTGGATCACGGTTCTCGGCGAAGCGCCGCCCTCGACGTTGCAGCAGTTCGCGTCTGCCATAGAATACAAGGCTTCCAA
GTAACCCTTCGGTTTCCGAC

Downstream 100 bases:

>100_bases
GCGCCGCCGTGCGTTTCACGCTGTACGGCCGCGGCTGGTGCCATTTGTGCGACGAGATGCGAGACGCGCTCGCGCCCGTG
GCGGCCGAATGCTCGGCGAG

Product: Do family protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MMNPSLRTWLVAAAVTALTPLAAQSATAAPNVTTTPAATGAAPAARAGLPDFADLVERVGPAVVNIRTTANVPADTRGAL
PPGLDNGDMSEFFRRFFGIPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKRE
FKAKLIGVDERTDVAIVKINASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVN
PGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLPKAE
GALVSSVEPGGPADKAGLQPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKAD
SRQAPQQKPRSSALGLTVSDLSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQR
AVAVLVRRGENTQFIPIRPRQK

Sequences:

>Translated_502_residues
MMNPSLRTWLVAAAVTALTPLAAQSATAAPNVTTTPAATGAAPAARAGLPDFADLVERVGPAVVNIRTTANVPADTRGAL
PPGLDNGDMSEFFRRFFGIPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKRE
FKAKLIGVDERTDVAIVKINASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVN
PGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLPKAE
GALVSSVEPGGPADKAGLQPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKAD
SRQAPQQKPRSSALGLTVSDLSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQR
AVAVLVRRGENTQFIPIRPRQK
>Mature_502_residues
MMNPSLRTWLVAAAVTALTPLAAQSATAAPNVTTTPAATGAAPAARAGLPDFADLVERVGPAVVNIRTTANVPADTRGAL
PPGLDNGDMSEFFRRFFGIPLPQGPGGQKNAPSTPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKRE
FKAKLIGVDERTDVAIVKINASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVN
PGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIAVAIGEVTKEVADSIGLPKAE
GALVSSVEPGGPADKAGLQPGDIILKFNGRPVEAASDLPRMVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKAD
SRQAPQQKPRSSALGLTVSDLSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQR
AVAVLVRRGENTQFIPIRPRQK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=355, Percent_Identity=34.6478873239437, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI22129776, Length=339, Percent_Identity=34.8082595870207, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=35.6, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=39.8406374501992, Blast_Score=146, Evalue=4e-35,
Organism=Escherichia coli, GI1789629, Length=462, Percent_Identity=35.9307359307359, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1786356, Length=490, Percent_Identity=33.8775510204082, Blast_Score=243, Evalue=3e-65,
Organism=Escherichia coli, GI1789630, Length=277, Percent_Identity=39.7111913357401, Blast_Score=193, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=37.4045801526718, Blast_Score=159, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 52451; Mature: 52451

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNPSLRTWLVAAAVTALTPLAAQSATAAPNVTTTPAATGAAPAARAGLPDFADLVERVG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCC
PAVVNIRTTANVPADTRGALPPGLDNGDMSEFFRRFFGIPLPQGPGGQKNAPSTPDAPDT
CEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
EQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERTDVAIVKIN
HHCCCCCCCEEECCCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEE
ASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVN
CCCCCEEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEEC
PGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIA
CCCCCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCEECCEEE
VAIGEVTKEVADSIGLPKAEGALVSSVEPGGPADKAGLQPGDIILKFNGRPVEAASDLPR
EEHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHH
MVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKADSRQAPQQKPRSSALGLTVSD
HHCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCHHCEEEEEC
LSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQR
CCHHHHHHHHHCCCCEEEECCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHH
AVAVLVRRGENTQFIPIRPRQK
HHHHHEECCCCCEEEECCCCCC
>Mature Secondary Structure
MMNPSLRTWLVAAAVTALTPLAAQSATAAPNVTTTPAATGAAPAARAGLPDFADLVERVG
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHCC
PAVVNIRTTANVPADTRGALPPGLDNGDMSEFFRRFFGIPLPQGPGGQKNAPSTPDAPDT
CEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
EQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERTDVAIVKIN
HHCCCCCCCEEECCCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCCCEEEEEEE
ASSLPTVAIGDSNRVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPFIQTDVAVN
CCCCCEEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEEECEEEC
PGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKASGKVTRGRIA
CCCCCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCEECCEEE
VAIGEVTKEVADSIGLPKAEGALVSSVEPGGPADKAGLQPGDIILKFNGRPVEAASDLPR
EEHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHCCCCCCCEEEEECCCCCCHHHHHHH
MVGDTKPGAKATVTVWRKGQSRDLPITIAEFPADKAAKADSRQAPQQKPRSSALGLTVSD
HHCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCHHCEEEEEC
LSPEQLKTLKLRNGVQIDAVDGPASRAGLQRGDIVLRVGDVDITSAKQFVDVTSKLDPQR
CCHHHHHHHHHCCCCEEEECCCCHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCHHH
AVAVLVRRGENTQFIPIRPRQK
HHHHHEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]