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The map label for this gene is ywlC [H]

Identifier: 126453889

GI number: 126453889

Start: 825733

End: 826758

Strand: Direct

Name: ywlC [H]

Synonym: BURPS1106A_0845

Alternate gene names: 126453889

Gene position: 825733-826758 (Clockwise)

Preceding gene: 126454636

Following gene: 126452671

Centisome position: 20.7

GC content: 74.07

Gene sequence:

>1026_bases
ATGTCGAACGATCGACCCTTCCCGAGCGCCGAGGCCATCGAGGACGCGGCCGCGCGGCTCGATGCGGGCGAGCTCGTCGC
GTTTCCGACCGAGACCGTCTACGGGCTCGGCGCCGACGCGCAGAACCCGGCCGCCGTCGCGCGCATCTACGCGGCGAAAG
GGCGGCCGGCGAACCATCCGGTGATCGTCCATCTCGCGCCGGGCAGCGATCCCGGTTATTGGGTCGAAGCGTTGCCCGCC
GACGCGAAGAAGCTGATCGACGCGTTCTGGCCCGGCCCGCTCACGCTGATCCTGAAGCGCGCCACGCACATTCCGGACGC
GGTGAGCGGCGGGCAGGACTCGGTCGGCTTGCGCTGTCCGTCGCATCCGGTCGCGCAGGCGCTGCTGCGCGCGTTCGACG
CGCGGCGCGGCGGGCACGGCGGCGTCGCCGCGCCGTCGGCGAACCGCTTCGGCCACGTGAGCCCGACCACCGCGCAGCAC
GTGCGCGACGAGTTCGGCGATGCCGTCCATGTGCTCGATGGCGGCCCGTCCGACGTCGGCATCGAATCGACGATTCTCGA
TTTGTCGCGCGGCTTTCCGGCGCTGCTGCGCCCGGGCCATGTGAGCCCGCGGCAGATCGCCGACGTGCTTGGCGTCGCGC
CGCGCCTGCCCGACGGCAGCGACGCAACCGCGCCGCGCGCGTCCGGCACGCTCAAGGCGCATTACGCGCCGCGCACGCCG
CTTGCGCTCGCGGCGTTCGAGCGGCTCGAGCCGCTGCTCGCGGCCGCGCGCGACACGGGCGAACCGGTGGCGCTCGTCGC
GCGCGCGTCGCGCGCCGGCGCGTGGGCGCATGCGGCGGGCGTGCATTTCGTCGCGGCGCCCGAGGATCCGGCGGCGTACG
CGCGCGAGCTCTACGGGTTGCTGCGCGCGCTCGATCGTGCGCAGGTCGCGCGCATTCTCGTCGAGAAGCTGCCCGATACG
GCCGAATGGACGGCGGTAAACGACCGGCTCGGCCGCGCGGCGGCGGCGTTCGACGCGCAGGCGTGA

Upstream 100 bases:

>100_bases
GCCATGTGAACTTCACCGCGGCGACGCGCGACGAAGCGGTCGCCGGCGCGACCGCGTGCGCGCGGCTGTTGCGCATTGCG
CTCGACTGACGGAGCGCGCG

Downstream 100 bases:

>100_bases
GCGCCGGCCGGGCGGGCCGCTGATCCGGCGGGCGGGAGCGAGCGCGGCTGCGTTATGCTGCTGTCGCCGAAGCCGAAGCC
GAAGCCGAAGCCGAAGCCGA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSNDRPFPSAEAIEDAAARLDAGELVAFPTETVYGLGADAQNPAAVARIYAAKGRPANHPVIVHLAPGSDPGYWVEALPA
DAKKLIDAFWPGPLTLILKRATHIPDAVSGGQDSVGLRCPSHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQH
VRDEFGDAVHVLDGGPSDVGIESTILDLSRGFPALLRPGHVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
LALAAFERLEPLLAAARDTGEPVALVARASRAGAWAHAAGVHFVAAPEDPAAYARELYGLLRALDRAQVARILVEKLPDT
AEWTAVNDRLGRAAAAFDAQA

Sequences:

>Translated_341_residues
MSNDRPFPSAEAIEDAAARLDAGELVAFPTETVYGLGADAQNPAAVARIYAAKGRPANHPVIVHLAPGSDPGYWVEALPA
DAKKLIDAFWPGPLTLILKRATHIPDAVSGGQDSVGLRCPSHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQH
VRDEFGDAVHVLDGGPSDVGIESTILDLSRGFPALLRPGHVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
LALAAFERLEPLLAAARDTGEPVALVARASRAGAWAHAAGVHFVAAPEDPAAYARELYGLLRALDRAQVARILVEKLPDT
AEWTAVNDRLGRAAAAFDAQA
>Mature_340_residues
SNDRPFPSAEAIEDAAARLDAGELVAFPTETVYGLGADAQNPAAVARIYAAKGRPANHPVIVHLAPGSDPGYWVEALPAD
AKKLIDAFWPGPLTLILKRATHIPDAVSGGQDSVGLRCPSHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQHV
RDEFGDAVHVLDGGPSDVGIESTILDLSRGFPALLRPGHVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTPL
ALAAFERLEPLLAAARDTGEPVALVARASRAGAWAHAAGVHFVAAPEDPAAYARELYGLLRALDRAQVARILVEKLPDTA
EWTAVNDRLGRAAAAFDAQA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=196, Percent_Identity=31.6326530612245, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367210, Length=170, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=381, Percent_Identity=29.6587926509186, Blast_Score=129, Evalue=5e-31,
Organism=Drosophila melanogaster, GI78707274, Length=200, Percent_Identity=26, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 35554; Mature: 35423

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDRPFPSAEAIEDAAARLDAGELVAFPTETVYGLGADAQNPAAVARIYAAKGRPANHP
CCCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHEECCCCCCCHHHHHHHHHHCCCCCCCC
VIVHLAPGSDPGYWVEALPADAKKLIDAFWPGPLTLILKRATHIPDAVSGGQDSVGLRCP
EEEEECCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCC
SHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDAVHVLDGGPSDVG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCC
IESTILDLSRGFPALLRPGHVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
HHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LALAAFERLEPLLAAARDTGEPVALVARASRAGAWAHAAGVHFVAAPEDPAAYARELYGL
HHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHCCEEEEECCCCHHHHHHHHHHH
LRALDRAQVARILVEKLPDTAEWTAVNDRLGRAAAAFDAQA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNDRPFPSAEAIEDAAARLDAGELVAFPTETVYGLGADAQNPAAVARIYAAKGRPANHP
CCCCCCCCHHHHHHHHHHCCCCCEEECCCHHHEECCCCCCCHHHHHHHHHHCCCCCCCC
VIVHLAPGSDPGYWVEALPADAKKLIDAFWPGPLTLILKRATHIPDAVSGGQDSVGLRCP
EEEEECCCCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCCCCCCCC
SHPVAQALLRAFDARRGGHGGVAAPSANRFGHVSPTTAQHVRDEFGDAVHVLDGGPSDVG
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCC
IESTILDLSRGFPALLRPGHVSPRQIADVLGVAPRLPDGSDATAPRASGTLKAHYAPRTP
HHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCC
LALAAFERLEPLLAAARDTGEPVALVARASRAGAWAHAAGVHFVAAPEDPAAYARELYGL
HHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHCCEEEEECCCCHHHHHHHHHHH
LRALDRAQVARILVEKLPDTAEWTAVNDRLGRAAAAFDAQA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]