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The map label for this gene is ttuB [H]

Identifier: 126453873

GI number: 126453873

Start: 2136606

End: 2137883

Strand: Reverse

Name: ttuB [H]

Synonym: BURPS1106A_2153

Alternate gene names: 126453873

Gene position: 2137883-2136606 (Counterclockwise)

Preceding gene: 126454815

Following gene: 126455132

Centisome position: 53.6

GC content: 68.0

Gene sequence:

>1278_bases
ATGTCCGCAACGCTCGCGATTCGCCGCTGGTGGACGATCATGCCGATCGTCTTCATCACCTACAGCCTCGCGTATCTCGA
CCGCGCGAACTACGGCTTCGCCGCCGCGGCCGGGATCAACCAGGATCTCGGCATCAGCAAGGGGCTGTCCTCGCTGATCG
GCGCGCTGTTCTTCCTCGGCTACTTCTTCTTCCAGATTCCGGGCGCGATCTATGCGGAGCGTCGCAGCGTGAAGACGCTC
GTGTTCTGGAGCCTCGTGCTGTGGGGCGCGTGCGCGTCGCTCACGGGCGTCGTGAGCAACATCCCGTCGCTGATGGCGAT
CCGCTTCCTGCTCGGCGTCGTCGAGGCGGCCGTGATGCCCGCGATGCTGATCTTCATCAGCAACTGGTTCACGAAGCGCG
AGCGCTCGCGCGCGAACACGTTCCTCATTCTCGGCAACCCGGTGACGGTGCTGTGGATGTCGGTCGTCTCCGGCTACCTC
GTCCACGAGTTCGGCTGGCGCCACATGTTCGTCGCCGAAGGGTTGCCCGCGATCGTCTGGGCACTCTGCTGGTGGTGCCT
CGTGCAGGACAAGCCCGCGCAGGCGAAGTGGCTCACCGGCGACGAGAGGCGCGCGCTCGACGCGGCGCTCGCGGCCGAGC
AGGCGGCGCTCAAGCCGGTGCGCAACTATCGCGACGCGTTTCGCTCGCCCGCCGTCGTCAAGCTCTGCGCGCAGTACTTC
TGCTGGAGCATCGGCGTGTACGGCTTCGTGTTGTGGCTGCCGTCGATCGTGAAGAACGGCTCGGCGCTCGGCATGGTCGC
AACGGGGTGGCTGTCCGCGCTGCCGTATCTCGCCGCGACGATCGCGATGCTCGCCGCGTCGTGGGCGTCCGACCGGCTCG
GCTCGCGCAAGGGCTTCGTGTGGCCGTTCCTGCTGATCGGCGCAGCCGCGTTCGCCGCGTCGTACACGCTCGGCTCGACG
CACTTCTGGCTGTCGTATGCGCTGCTCGTCGTCGCGGGCGCGGCGATGTACGCGCCGTACGGGCCGTTCTTCGCGATCGT
GCCGGAGCTCCTGCCGAAGAACGTCGCGGGCGGCGCGATGGCGCTCATCAACAGCATGGGCGCGCTCGGCTCGTTCGTCG
GCTCGTATGCGGTCGGCTATCTGAACGGCGCGACGGGCTCGCCCGCCGCGTCCTACGCGTTCATGAGCGCCGCGCTCGTC
GCGGCCGTCGTGCTCACGCTGTCGGTGAAGCAGCCGGGCGCGACGCCGCCGCTCGCCCATCCGTTGCAAGGAAAGTGA

Upstream 100 bases:

>100_bases
GCCGCTCGCGCGATAAACCGCCTGTCCCGACGCAGGACGGGCACAATCGCGGCGAATCCCGCGTTTCATACGGCGCCGCT
CGACACAGGAGACACACATC

Downstream 100 bases:

>100_bases
AGATATGAAGCATCGCATCGTCGTCTACAAGCCGCTCCCCGACGACGTGCTCGCGGCCTTGCGCGCGCGCGCCGACGTCG
TGCTCGCCGAGGGCGCCGAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKTL
VFWSLVLWGACASLTGVVSNIPSLMAIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYL
VHEFGWRHMFVAEGLPAIVWALCWWCLVQDKPAQAKWLTGDERRALDAALAAEQAALKPVRNYRDAFRSPAVVKLCAQYF
CWSIGVYGFVLWLPSIVKNGSALGMVATGWLSALPYLAATIAMLAASWASDRLGSRKGFVWPFLLIGAAAFAASYTLGST
HFWLSYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYAVGYLNGATGSPAASYAFMSAALV
AAVVLTLSVKQPGATPPLAHPLQGK

Sequences:

>Translated_425_residues
MSATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKTL
VFWSLVLWGACASLTGVVSNIPSLMAIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYL
VHEFGWRHMFVAEGLPAIVWALCWWCLVQDKPAQAKWLTGDERRALDAALAAEQAALKPVRNYRDAFRSPAVVKLCAQYF
CWSIGVYGFVLWLPSIVKNGSALGMVATGWLSALPYLAATIAMLAASWASDRLGSRKGFVWPFLLIGAAAFAASYTLGST
HFWLSYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYAVGYLNGATGSPAASYAFMSAALV
AAVVLTLSVKQPGATPPLAHPLQGK
>Mature_424_residues
SATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKTLV
FWSLVLWGACASLTGVVSNIPSLMAIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYLV
HEFGWRHMFVAEGLPAIVWALCWWCLVQDKPAQAKWLTGDERRALDAALAAEQAALKPVRNYRDAFRSPAVVKLCAQYFC
WSIGVYGFVLWLPSIVKNGSALGMVATGWLSALPYLAATIAMLAASWASDRLGSRKGFVWPFLLIGAAAFAASYTLGSTH
FWLSYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYAVGYLNGATGSPAASYAFMSAALVA
AVVLTLSVKQPGATPPLAHPLQGK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=394, Percent_Identity=25.6345177664975, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI6912666, Length=245, Percent_Identity=25.3061224489796, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI9945322, Length=388, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI21322234, Length=259, Percent_Identity=26.2548262548263, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI154350196, Length=367, Percent_Identity=23.1607629427793, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082071, Length=418, Percent_Identity=27.2727272727273, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87082320, Length=432, Percent_Identity=24.7685185185185, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789152, Length=438, Percent_Identity=22.6027397260274, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI2367379, Length=287, Percent_Identity=24.390243902439, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789515, Length=433, Percent_Identity=23.5565819861432, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17552542, Length=319, Percent_Identity=26.3322884012539, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115533556, Length=362, Percent_Identity=24.0331491712707, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=436, Percent_Identity=26.605504587156, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=362, Percent_Identity=24.0331491712707, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=255, Percent_Identity=25.8823529411765, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=193, Percent_Identity=25.3886010362694, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560030, Length=274, Percent_Identity=21.5328467153285, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=255, Percent_Identity=25.8823529411765, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32565914, Length=193, Percent_Identity=25.3886010362694, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=273, Percent_Identity=24.9084249084249, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=197, Percent_Identity=26.9035532994924, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17566884, Length=182, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=230, Percent_Identity=23.0434782608696, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24580790, Length=349, Percent_Identity=25.7879656160458, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI45550460, Length=405, Percent_Identity=25.679012345679, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24655255, Length=367, Percent_Identity=26.158038147139, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24583789, Length=356, Percent_Identity=23.5955056179775, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24655271, Length=412, Percent_Identity=23.0582524271845, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20130135, Length=411, Percent_Identity=23.1143552311436, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24584153, Length=392, Percent_Identity=22.4489795918367, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI28573299, Length=300, Percent_Identity=23.3333333333333, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648416, Length=273, Percent_Identity=23.8095238095238, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356189, Length=273, Percent_Identity=23.8095238095238, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639764, Length=297, Percent_Identity=23.2323232323232, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24654215, Length=359, Percent_Identity=23.6768802228412, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922400, Length=359, Percent_Identity=23.6768802228412, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19920686, Length=371, Percent_Identity=24.7978436657682, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573708, Length=264, Percent_Identity=23.1060606060606, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573707, Length=264, Percent_Identity=23.1060606060606, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653727, Length=375, Percent_Identity=25.0666666666667, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24658674, Length=282, Percent_Identity=22.6950354609929, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI62484226, Length=295, Percent_Identity=24.406779661017, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45780; Mature: 45649

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure 
SATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]