Click here to switch to the map view.

The map label for this gene is 126453790

Identifier: 126453790

GI number: 126453790

Start: 3821548

End: 3823101

Strand: Direct

Name: 126453790

Synonym: BURPS1106A_3916

Alternate gene names: NA

Gene position: 3821548-3823101 (Clockwise)

Preceding gene: 126452818

Following gene: 126455246

Centisome position: 95.82

GC content: 72.84

Gene sequence:

>1554_bases
GTGGGCGCGCGCCGTGCCGCCGCGCTCGAATTCCGAATCGTTCGCCGCTCGTCACCACGGGGGATGACTGTGCCGTCCGA
CTATCTGTGCCACGACGCAATCGGGCTCGCGCAGCTCGTCGCGCAGCGCGAAGTCAGCGCGCGCGAACTGCTCGACGCCG
CGATCGGCCGCGCGCAAGCGCTCAATCCGGCGATCAACGCGATCGTGCTGAACGACTACGCGGCCGCGCGCGAGCGCGCG
GCGAGCGGCACGCTCGCGGGCCCGCTCGCCGGCGTGCCGTATCTCGTCAAGGATCTCGGCTCCGCGGTCGCGGGGCTGCC
GCTGTCGCTCGGCAGCCGTCACTATCGCCATCATGTGCCGGCCGAGGATTCGCCGCTCATCGTGCGAACGAAGGCCGCCG
GGCTCAACATCTTCGGCAAGACCAACACGCCCGAGCTCGGGCAGATGCCGTACACCGAATCGGCGCTGCTCGGCGTGTGC
CGCAACCCGTGGAACCTCGATCACACGCCGGGCGGCTCGAGCGGCGGCGCGGCGGCGGCCGTCGCCGCGGGCATCGTGCC
GCTCGCGCATGCGTCCGACGGCGGCGGCTCGATCCGGATTCCCGCGTCGTGCTGCGGCCTGTTCGGCTTCAAGCCGTCGC
GCGACCCGGCGCTGACACCGTGGCCCGTGCCGGGCGAGATCGTCGTCGAGCATGCGGTGTCGCGCAGCGTGCGCGACAGC
GCGCTGCTGCTCGACATCACGACCGGGCGAACCGCGCCGGGCACGCTCGAAGGCGTCGGCGCGCCCGGCACGTATCTCGG
CGCGCTCGACGCGCCGCCGCCCGCGCTGAAGATCGGCTACGTGACGGACCCGATGCTCGCGCCGGCGCTGTCGGCCGACG
TGCGCGACGCGCTCGATCGCGCGGCGGCGCTTGCCGCATCGCTCGGGCACAACGTCGAGCCGGCGGCGCTCAACCTCGAT
TTCGCGCAGATCGGCGAGGTATTCCTGACGATCTGGGCCGCGATCGCCGACGAGCTCGTGCTCGGCGCGGAGCGCATCAC
CGGGCGCAAGCCCGCGCGCGCCGAATTCGAGCCGGCGACGTGGGCGATGGCGCAGGTCGGCCGCCGGCTCGTGCGTGAGC
GGCTGCCGCACGCGCTCGAGCTGCAGCGGCAGATCACCGCGCGCGTCGCGGGCCTCGTGTCGCGCTACGACGTGCTGCTG
TGCGCGACGCTCGCCGCGCCGCCGATCAAGATCGGCGAAATGCAGCCGACGCCGCTCGAGACGCGGCAGATGGAGCTGCT
CGGCGTGCTGCCGATAAAGCCGCTCCTCAAGCGCATGCTCGCGGAGGTGTCGCACCAGGCGTTCGCGTGGGCGGGCTGCA
CGGAGCTCTTCAACCTGACCGGGCAGCCGGCGATGTCGGTGCCGCTGCACTGGAGCGCGCGCGGGCTGCCGGTCGGCGTC
CAGTTCGTCGCACGGCACGGTGACGATGCGCGCCTGTTCGCGCTCGCGCGTCAGCTCGAGCTCGCGCAGCCGTGGTTTGA
CAAACGCCCGCCGCTCGCACGCGCGCAGGCGTGA

Upstream 100 bases:

>100_bases
TCGTACGACCAGCGCGCGGCGGCGCTCGCGCACGGCCGCACGCTGACTTTCCTCGCCGAACGCCTGTAAGCCGCCGGCGA
TCGCCGCGCTCGCGCGGCGC

Downstream 100 bases:

>100_bases
ATGCGAGCGAGAGTGTGAGTGTAAGCAGCGGACCACGAGCGACAGCGGTGCGCCGTCTCGCGCTGCGCCTCGCAGGCCGG
CGCGTTGCCCTTCATGTCCG

Product: amidase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MGARRAAALEFRIVRRSSPRGMTVPSDYLCHDAIGLAQLVAQREVSARELLDAAIGRAQALNPAINAIVLNDYAAARERA
ASGTLAGPLAGVPYLVKDLGSAVAGLPLSLGSRHYRHHVPAEDSPLIVRTKAAGLNIFGKTNTPELGQMPYTESALLGVC
RNPWNLDHTPGGSSGGAAAAVAAGIVPLAHASDGGGSIRIPASCCGLFGFKPSRDPALTPWPVPGEIVVEHAVSRSVRDS
ALLLDITTGRTAPGTLEGVGAPGTYLGALDAPPPALKIGYVTDPMLAPALSADVRDALDRAAALAASLGHNVEPAALNLD
FAQIGEVFLTIWAAIADELVLGAERITGRKPARAEFEPATWAMAQVGRRLVRERLPHALELQRQITARVAGLVSRYDVLL
CATLAAPPIKIGEMQPTPLETRQMELLGVLPIKPLLKRMLAEVSHQAFAWAGCTELFNLTGQPAMSVPLHWSARGLPVGV
QFVARHGDDARLFALARQLELAQPWFDKRPPLARAQA

Sequences:

>Translated_517_residues
MGARRAAALEFRIVRRSSPRGMTVPSDYLCHDAIGLAQLVAQREVSARELLDAAIGRAQALNPAINAIVLNDYAAARERA
ASGTLAGPLAGVPYLVKDLGSAVAGLPLSLGSRHYRHHVPAEDSPLIVRTKAAGLNIFGKTNTPELGQMPYTESALLGVC
RNPWNLDHTPGGSSGGAAAAVAAGIVPLAHASDGGGSIRIPASCCGLFGFKPSRDPALTPWPVPGEIVVEHAVSRSVRDS
ALLLDITTGRTAPGTLEGVGAPGTYLGALDAPPPALKIGYVTDPMLAPALSADVRDALDRAAALAASLGHNVEPAALNLD
FAQIGEVFLTIWAAIADELVLGAERITGRKPARAEFEPATWAMAQVGRRLVRERLPHALELQRQITARVAGLVSRYDVLL
CATLAAPPIKIGEMQPTPLETRQMELLGVLPIKPLLKRMLAEVSHQAFAWAGCTELFNLTGQPAMSVPLHWSARGLPVGV
QFVARHGDDARLFALARQLELAQPWFDKRPPLARAQA
>Mature_516_residues
GARRAAALEFRIVRRSSPRGMTVPSDYLCHDAIGLAQLVAQREVSARELLDAAIGRAQALNPAINAIVLNDYAAARERAA
SGTLAGPLAGVPYLVKDLGSAVAGLPLSLGSRHYRHHVPAEDSPLIVRTKAAGLNIFGKTNTPELGQMPYTESALLGVCR
NPWNLDHTPGGSSGGAAAAVAAGIVPLAHASDGGGSIRIPASCCGLFGFKPSRDPALTPWPVPGEIVVEHAVSRSVRDSA
LLLDITTGRTAPGTLEGVGAPGTYLGALDAPPPALKIGYVTDPMLAPALSADVRDALDRAAALAASLGHNVEPAALNLDF
AQIGEVFLTIWAAIADELVLGAERITGRKPARAEFEPATWAMAQVGRRLVRERLPHALELQRQITARVAGLVSRYDVLLC
ATLAAPPIKIGEMQPTPLETRQMELLGVLPIKPLLKRMLAEVSHQAFAWAGCTELFNLTGQPAMSVPLHWSARGLPVGVQ
FVARHGDDARLFALARQLELAQPWFDKRPPLARAQA

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=218, Percent_Identity=33.9449541284404, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI222831590, Length=530, Percent_Identity=24.3396226415094, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17537465, Length=215, Percent_Identity=30.6976744186047, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17556276, Length=332, Percent_Identity=28.0120481927711, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17556264, Length=304, Percent_Identity=27.3026315789474, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17556278, Length=332, Percent_Identity=28.0120481927711, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538252, Length=127, Percent_Identity=36.2204724409449, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17543272, Length=454, Percent_Identity=24.4493392070485, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71990152, Length=351, Percent_Identity=27.0655270655271, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320448, Length=197, Percent_Identity=32.994923857868, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24648435, Length=520, Percent_Identity=26.3461538461538, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24648437, Length=520, Percent_Identity=26.3461538461538, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45550774, Length=520, Percent_Identity=26.3461538461538, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644968, Length=526, Percent_Identity=25.0950570342205, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24648441, Length=428, Percent_Identity=26.1682242990654, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24648439, Length=428, Percent_Identity=26.1682242990654, Blast_Score=99, Evalue=8e-21,
Organism=Drosophila melanogaster, GI21356731, Length=198, Percent_Identity=31.3131313131313, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI161078093, Length=546, Percent_Identity=25.6410256410256, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24652985, Length=321, Percent_Identity=27.1028037383178, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19922090, Length=321, Percent_Identity=27.1028037383178, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652981, Length=321, Percent_Identity=27.1028037383178, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652983, Length=321, Percent_Identity=27.1028037383178, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648113, Length=453, Percent_Identity=27.8145695364238, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 54582; Mature: 54450

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARRAAALEFRIVRRSSPRGMTVPSDYLCHDAIGLAQLVAQREVSARELLDAAIGRAQA
CCCCHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPAINAIVLNDYAAARERAASGTLAGPLAGVPYLVKDLGSAVAGLPLSLGSRHYRHHVP
CCCHHEEEEECCHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHCCCHHHCCCHHHCCCC
AEDSPLIVRTKAAGLNIFGKTNTPELGQMPYTESALLGVCRNPWNLDHTPGGSSGGAAAA
CCCCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHH
VAAGIVPLAHASDGGGSIRIPASCCGLFGFKPSRDPALTPWPVPGEIVVEHAVSRSVRDS
HHHHHHHEEECCCCCCEEEECHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
ALLLDITTGRTAPGTLEGVGAPGTYLGALDAPPPALKIGYVTDPMLAPALSADVRDALDR
EEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
AAALAASLGHNVEPAALNLDFAQIGEVFLTIWAAIADELVLGAERITGRKPARAEFEPAT
HHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
WAMAQVGRRLVRERLPHALELQRQITARVAGLVSRYDVLLCATLAAPPIKIGEMQPTPLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
TRQMELLGVLPIKPLLKRMLAEVSHQAFAWAGCTELFNLTGQPAMSVPLHWSARGLPVGV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCH
QFVARHGDDARLFALARQLELAQPWFDKRPPLARAQA
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GARRAAALEFRIVRRSSPRGMTVPSDYLCHDAIGLAQLVAQREVSARELLDAAIGRAQA
CCCHHHHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPAINAIVLNDYAAARERAASGTLAGPLAGVPYLVKDLGSAVAGLPLSLGSRHYRHHVP
CCCHHEEEEECCHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHHHCCCHHHCCCHHHCCCC
AEDSPLIVRTKAAGLNIFGKTNTPELGQMPYTESALLGVCRNPWNLDHTPGGSSGGAAAA
CCCCCEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHH
VAAGIVPLAHASDGGGSIRIPASCCGLFGFKPSRDPALTPWPVPGEIVVEHAVSRSVRDS
HHHHHHHEEECCCCCCEEEECHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
ALLLDITTGRTAPGTLEGVGAPGTYLGALDAPPPALKIGYVTDPMLAPALSADVRDALDR
EEEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
AAALAASLGHNVEPAALNLDFAQIGEVFLTIWAAIADELVLGAERITGRKPARAEFEPAT
HHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
WAMAQVGRRLVRERLPHALELQRQITARVAGLVSRYDVLLCATLAAPPIKIGEMQPTPLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
TRQMELLGVLPIKPLLKRMLAEVSHQAFAWAGCTELFNLTGQPAMSVPLHWSARGLPVGV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCH
QFVARHGDDARLFALARQLELAQPWFDKRPPLARAQA
HHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]