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The map label for this gene is phoP [H]

Identifier: 126453771

GI number: 126453771

Start: 1537493

End: 1538185

Strand: Direct

Name: phoP [H]

Synonym: BURPS1106A_1588

Alternate gene names: 126453771

Gene position: 1537493-1538185 (Clockwise)

Preceding gene: 126455451

Following gene: 126453141

Centisome position: 38.55

GC content: 65.37

Gene sequence:

>693_bases
GTGCTTATTTACCTGATCGAGGACGACGAGGTCCAGGCGCGGTGTTACGCGGCCATCCTGCAGCATGCCGGTTACAGCGT
GCGCGTCCTGCCGGACGGCGAGCGCGCGTTGCGCGAGATACAGCGCGCGGCGCCCGACCTGATCGTGCTGGACCGGCGCC
TGCCGGACATCGACGGCCTGGAGATCATCGCGTGGGTGCGCGAGCGCTGCGCGCCGCTGCCGATACTCGTGCTGACCAAC
GCGGTGCTCGAGACCGATCTCGTCGAAGCGCTCGAGGCGGGCGCCGACGACTATCTGATCAAGCCGCCACGAGAACGGGA
ATTCGTTGCCCGCGTCAATGCGCTTCGCCGCCGCGCGAGCATCAGCAAGCAATTCGAAGGCACGATCGAAATCGGCGGCT
ACCGGATCGCGACCGTCGAGCGCGCCGTCTATCTCGCGGGCGAGCGCATTCCGTTGTCGCCGAAGGAGTACGAGATCGTC
GAGTTGCTCGCGCGGCACGTCGGGCAGGTCGTGCCGCGCAAGACCATCATCAGCCGCGTCTGGGGGCGCGCGGCCGAGGA
GGAAGTTTCCCGTTCGCTCGACACCCACATCTACCGCATCCGCAGGAAGATGAATCTGTCGCGCCGCAATGGCGCGATGC
TTCGCGTCATCTATACGCATGGATTCCGGCTGGACGATTTTAGCCATGTGTGA

Upstream 100 bases:

>100_bases
CTGTTCAAGCAGTGCACGATTCCGGCTTGCCCGTTCCTCGAGGTTCGGGGGGCGGTTCGTCGGGCTGCTGCGTGGTCGCT
GGTTGTCGAGACAAAAAGTG

Downstream 100 bases:

>100_bases
TTGCTTATTCGAGATAGCGGCGCGCGTGAGACAAGTGCCGTTTCTAATTGGATGACGATATTTTTGAGATATTGAATGTG
CGGCGCGCGGCGATGGCGAG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGLEIIAWVRERCAPLPILVLTN
AVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPKEYEIV
ELLARHVGQVVPRKTIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV

Sequences:

>Translated_230_residues
MLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGLEIIAWVRERCAPLPILVLTN
AVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPKEYEIV
ELLARHVGQVVPRKTIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV
>Mature_230_residues
MLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGLEIIAWVRERCAPLPILVLTN
AVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRASISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPKEYEIV
ELLARHVGQVVPRKTIISRVWGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=208, Percent_Identity=33.1730769230769, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=31.25, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.1858407079646, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082012, Length=205, Percent_Identity=33.1707317073171, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1790860, Length=204, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=28.5067873303167, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=30.3571428571429, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787375, Length=206, Percent_Identity=33.495145631068, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786911, Length=202, Percent_Identity=31.1881188118812, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=215, Percent_Identity=31.6279069767442, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787229, Length=214, Percent_Identity=34.5794392523364, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI145693140, Length=212, Percent_Identity=31.6037735849057, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=25.3275109170306, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790437, Length=100, Percent_Identity=32, Blast_Score=61, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=100, Percent_Identity=31, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26335; Mature: 26335

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGL
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEECCCCCCCCCH
EIIAWVRERCAPLPILVLTNAVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRAS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHH
ISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPKEYEIVELLARHVGQVVPRKTIISRV
HHHHCCCEEEECCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
WGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEECCCCCCC
>Mature Secondary Structure
MLIYLIEDDEVQARCYAAILQHAGYSVRVLPDGERALREIQRAAPDLIVLDRRLPDIDGL
CEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCEEEECCCCCCCCCH
EIIAWVRERCAPLPILVLTNAVLETDLVEALEAGADDYLIKPPREREFVARVNALRRRAS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHH
ISKQFEGTIEIGGYRIATVERAVYLAGERIPLSPKEYEIVELLARHVGQVVPRKTIISRV
HHHHCCCEEEECCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHH
WGRAAEEEVSRSLDTHIYRIRRKMNLSRRNGAMLRVIYTHGFRLDDFSHV
HCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]