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The map label for this gene is gmhB [H]

Identifier: 126453758

GI number: 126453758

Start: 3191093

End: 3191662

Strand: Reverse

Name: gmhB [H]

Synonym: BURPS1106A_3275

Alternate gene names: 126453758

Gene position: 3191662-3191093 (Counterclockwise)

Preceding gene: 126454948

Following gene: 126452213

Centisome position: 80.02

GC content: 59.82

Gene sequence:

>570_bases
GTGAAGAATCGCGCGTTGTTCCTGGATCGTGATGGGGTGATCAATCGCGACGACGGCTATGTTTTCGAGATCGAGAAATT
TGTCTTTCTGGACGGAATTTTCGAGCTTGCCGGAGCCGCCAAGGCGTTGGGATATCTGAGCATCGTGGTGACGAACCAGG
CGGGGATCGGGCGCGGCTACTATTCGGAAGACGATTTTTTTCGCCTGTCCGACTGGATGAAAGGGGTCTTCGCGACCGAA
GGCGCGCCGATCGACGGCGTGTACTTTTGTCCGACACATCCCGAGCACGGCATTGGCCGATATAAGGTCGAGTCCCGGTT
CAGGAAGCCGAATCCGGGGATGATCCTCGCGGCGCAGCATGACTTCGATCTCGATCTGGGGGCGTCGTTACTTGTCGGGG
ATAAGGAGTCCGATATTCAAGCCGGGTCGACGGCGGGTGTCGGGACGACTCTCCTCATATGCGACCGGGACGCATCGCGT
GTGGCGACGACGGCGAGCGCCGTCGTCCGCAATCCGCGTGACGTCATTCCGTTCCTGACGGGCCCCGGACCGGATGCCGG
ATCGTTCTAG

Upstream 100 bases:

>100_bases
CTCGCAGGTTCGACGTTTTCGTGACGCGTGGGCAGTTTATCGATATCGGCGTTCCCGAGGACTTTTACCGCGCTCAAGAC
GAGCTTTCCGGAATCTGCAA

Downstream 100 bases:

>100_bases
GAGGCTTGGCACGGTCGACGTCGGGTGTTTCACGTATGCGTCGCGCAAGGTTGCATCGAGGAGCGTTATACGCTGCTCGT
GCAGGTGACACGTGCGCATG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKNRALFLDRDGVINRDDGYVFEIEKFVFLDGIFELAGAAKALGYLSIVVTNQAGIGRGYYSEDDFFRLSDWMKGVFATE
GAPIDGVYFCPTHPEHGIGRYKVESRFRKPNPGMILAAQHDFDLDLGASLLVGDKESDIQAGSTAGVGTTLLICDRDASR
VATTASAVVRNPRDVIPFLTGPGPDAGSF

Sequences:

>Translated_189_residues
MKNRALFLDRDGVINRDDGYVFEIEKFVFLDGIFELAGAAKALGYLSIVVTNQAGIGRGYYSEDDFFRLSDWMKGVFATE
GAPIDGVYFCPTHPEHGIGRYKVESRFRKPNPGMILAAQHDFDLDLGASLLVGDKESDIQAGSTAGVGTTLLICDRDASR
VATTASAVVRNPRDVIPFLTGPGPDAGSF
>Mature_189_residues
MKNRALFLDRDGVINRDDGYVFEIEKFVFLDGIFELAGAAKALGYLSIVVTNQAGIGRGYYSEDDFFRLSDWMKGVFATE
GAPIDGVYFCPTHPEHGIGRYKVESRFRKPNPGMILAAQHDFDLDLGASLLVGDKESDIQAGSTAGVGTTLLICDRDASR
VATTASAVVRNPRDVIPFLTGPGPDAGSF

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=149, Percent_Identity=44.2953020134228, Blast_Score=146, Evalue=7e-37,
Organism=Escherichia coli, GI87082027, Length=177, Percent_Identity=28.2485875706215, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20458; Mature: 20458

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRALFLDRDGVINRDDGYVFEIEKFVFLDGIFELAGAAKALGYLSIVVTNQAGIGRGY
CCCCEEEEECCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
YSEDDFFRLSDWMKGVFATEGAPIDGVYFCPTHPEHGIGRYKVESRFRKPNPGMILAAQH
CCCCCCEEHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEHHHCCCCCCCEEEEECC
DFDLDLGASLLVGDKESDIQAGSTAGVGTTLLICDRDASRVATTASAVVRNPRDVIPFLT
CCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEC
GPGPDAGSF
CCCCCCCCC
>Mature Secondary Structure
MKNRALFLDRDGVINRDDGYVFEIEKFVFLDGIFELAGAAKALGYLSIVVTNQAGIGRGY
CCCCEEEEECCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCC
YSEDDFFRLSDWMKGVFATEGAPIDGVYFCPTHPEHGIGRYKVESRFRKPNPGMILAAQH
CCCCCCEEHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEHHHCCCCCCCEEEEECC
DFDLDLGASLLVGDKESDIQAGSTAGVGTTLLICDRDASRVATTASAVVRNPRDVIPFLT
CCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEC
GPGPDAGSF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11373120; 12101286 [H]