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The map label for this gene is cobO [H]

Identifier: 126453726

GI number: 126453726

Start: 1915576

End: 1916178

Strand: Reverse

Name: cobO [H]

Synonym: BURPS1106A_1949

Alternate gene names: 126453726

Gene position: 1916178-1915576 (Counterclockwise)

Preceding gene: 126453668

Following gene: 126452925

Centisome position: 48.04

GC content: 67.16

Gene sequence:

>603_bases
ATGAAAACCGATTCCGAATCGCATCAACGCATGGCCGAGCGCCGCCGCGCGGGCCACGAGAAGAAGCAGGCGGCCGCGAC
CGTCGAGAAGGGGCTCTTGATCGTCCACACCGGCAACGGCAAGGGCAAGAGCACGGCCGCGTTCGGGATGGCCGTGCGGA
TGCTCGGCCACGGGATGCGCACGGGTGTCGTGCAGTTCATCAAGGGCGCGCTGCACACGTCCGAGCGCGATTTCCTCGGC
GCGAACGCGCAGTGCGACTTCGTCACGATGGGCGACGGCTACACGTGGAACACGCAGAACCGCGACGCCGACATCGCCAC
CGCGCGCCGCGGCTGGGACGAGGCACGCCGGATGATCGAGAGCGGTGATTACCGGATGGTGATCCTCGACGAGCTGAACA
CGGTGCTCAAGTACGAATACCTGCCGCTCGACGAAGTGCTCGCGACGCTCGCCGCGCGCGATCCGGCGCTGCACGTCGTC
GTGACGGGCCGGCATGCGCCCGACGCGCTCGTCGACGCGGCCGATCTCGTCACCGAAATGCGGCTCGTCAAGCATCCGTA
CAAGGAGCAAGGCGTGAAGGCGCAGCGCGGCGTGGAGTTCTGA

Upstream 100 bases:

>100_bases
GCGCTCGACGGCGTGACGGCCGCGCTCGCGGGCCCGCTGTGACGCGCGCCGCGCGCGGTCTTCCGATTCACGAACCCAAC
GACTCACAGGACTCCAGCCG

Downstream 100 bases:

>100_bases
CGCGATGCCCGCCTGCCCCGCGCTCTTCGTCGCCGCCGCCGCGTCCGGCCAGGGCAAGACGTCGGTGACGGCGGCGCTCG
CGCGCCATCACCGGCGGCTC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKTDSESHQRMAERRRAGHEKKQAAATVEKGLLIVHTGNGKGKSTAAFGMAVRMLGHGMRTGVVQFIKGALHTSERDFLG
ANAQCDFVTMGDGYTWNTQNRDADIATARRGWDEARRMIESGDYRMVILDELNTVLKYEYLPLDEVLATLAARDPALHVV
VTGRHAPDALVDAADLVTEMRLVKHPYKEQGVKAQRGVEF

Sequences:

>Translated_200_residues
MKTDSESHQRMAERRRAGHEKKQAAATVEKGLLIVHTGNGKGKSTAAFGMAVRMLGHGMRTGVVQFIKGALHTSERDFLG
ANAQCDFVTMGDGYTWNTQNRDADIATARRGWDEARRMIESGDYRMVILDELNTVLKYEYLPLDEVLATLAARDPALHVV
VTGRHAPDALVDAADLVTEMRLVKHPYKEQGVKAQRGVEF
>Mature_200_residues
MKTDSESHQRMAERRRAGHEKKQAAATVEKGLLIVHTGNGKGKSTAAFGMAVRMLGHGMRTGVVQFIKGALHTSERDFLG
ANAQCDFVTMGDGYTWNTQNRDADIATARRGWDEARRMIESGDYRMVILDELNTVLKYEYLPLDEVLATLAARDPALHVV
VTGRHAPDALVDAADLVTEMRLVKHPYKEQGVKAQRGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=195, Percent_Identity=44.1025641025641, Blast_Score=168, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22180; Mature: 22180

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDSESHQRMAERRRAGHEKKQAAATVEKGLLIVHTGNGKGKSTAAFGMAVRMLGHGMR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCHH
TGVVQFIKGALHTSERDFLGANAQCDFVTMGDGYTWNTQNRDADIATARRGWDEARRMIE
HHHHHHHHHHHCCCCCHHCCCCCCEEEEECCCCEEECCCCCCCHHHHHHCCHHHHHHHHH
SGDYRMVILDELNTVLKYEYLPLDEVLATLAARDPALHVVVTGRHAPDALVDAADLVTEM
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHH
RLVKHPYKEQGVKAQRGVEF
HHHHCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MKTDSESHQRMAERRRAGHEKKQAAATVEKGLLIVHTGNGKGKSTAAFGMAVRMLGHGMR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHCCHH
TGVVQFIKGALHTSERDFLGANAQCDFVTMGDGYTWNTQNRDADIATARRGWDEARRMIE
HHHHHHHHHHHCCCCCHHCCCCCCEEEEECCCCEEECCCCCCCHHHHHHCCHHHHHHHHH
SGDYRMVILDELNTVLKYEYLPLDEVLATLAARDPALHVVVTGRHAPDALVDAADLVTEM
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHH
RLVKHPYKEQGVKAQRGVEF
HHHHCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]