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The map label for this gene is otsA [H]

Identifier: 126453612

GI number: 126453612

Start: 1088647

End: 1090065

Strand: Direct

Name: otsA [H]

Synonym: BURPS1106A_1109

Alternate gene names: 126453612

Gene position: 1088647-1090065 (Clockwise)

Preceding gene: 126454138

Following gene: 126454137

Centisome position: 27.29

GC content: 67.44

Gene sequence:

>1419_bases
ATGAGCAGATTGATCGTGGTATCGAATCGCGTGGCGGCCGGCCAGGATGCGCGTCCGACGGCGGGCGGGCTGGCGGTCGG
CGTGCTCGACGCGTTGAAGGAGACGGGCGGCGTCTGGTTCGGCTGGAACGGCGAGATCGCCGGCGCGCCCGAGGAGCCCG
TGATCGAGCGGGACGGCAACGTGACCTATGCGACCGTCGGCCTGACCCGCCGCGACTACGACCAGTACTATCGCGGCTTC
TCGAATGCCACGCTGTGGCCGGTATTTCACTATCGCGGCGATCTCGCGCGCTTCGATCGCCAGGAATATGCCGGCTATCT
GCGCGTGAACTGCGCGCTCGCGAAGCAGTTGTGCGCGCTCGTGCAGCCCGACGACATCATCTGGGTGCACGACTATCACC
TGCTGCCGTTCGCGCACTGCCTGCGCGAGCTCGGCGTGAAGAACCCGATCGGCTTCTTCCTGCACATTCCCTTCCCGTCG
CCCGAGGTGCTGCGGACCGTGCCGCCGCATGAAGAGCTGATGAAGTTCATGTGCGCGTACGACGTCATCGGCCTGCAGAC
CGAAAGCGACAAGCAGGCGTTCGTCGATTACATCGAGCGGCGCGGGCTCGGCACGTCGAGCGAGGACGGGATCCTGCACG
CGCACGGCCGCGTCGTGAAGGTCGCCGCGTATCCGATCGGCATCTATCCGGACGCGATCGGCAAGGCGGCGATCGAATAC
GGCTCGCGCAAGGCGGTGAAGGCGCTGCGCGACACGATGCGCGAGCGCAAGCTCGTGATCAGCGTGGATCGCCTCGATTA
CTCGAAGGGCCTCGTCGAGCGCTTCCAGGCGTTCGAGCGGATGCTCGCGAATGCGCCGGGCTGGCAGGGGCGCGTGTCGC
TCGTGCAGATCGCGCCGCCGACCCGCTCCGACGTGCAGACCTATCAGCGCATCCGTCAGACCCTCGAAGGCGAGGCGGGG
CGCATCAACGGGCGCTTCGCGCAGCTCGACTGGACGCCGATCCAGTACCTGAACCGCAAATACGAGCGCAATCTGCTGAT
GGCGCTGTTCAGGCTGTCGCAGGTGGGCTATGTGACGCCGCTGCGCGACGGGATGAACCTCGTCGCGAAGGAGTACGTCG
CGTCGCAGGATCCGAACGATCCGGGCGTGCTCGTGCTCTCCGAGTTCGCGGGCGCCGCGGCCGAGCTGCCGGGCGCGCTG
CTCGTGAACCCGTTCGATCTGTCGCAGATGGCCGAATCGCTCGAGCGCGCGCTCGCGATGCCGCTCGAGGAGCGGCAGGC
GCGGCACGCGGAGAACATCGCGCGGCTGCGCAAGAACGATCTGTCGGTGTGGCGCGATTCGTTCCTCACGGATCTGCGCA
GCGTCGCGACGGCCGCGTCCGTCACGCAGCGCGCCGGACGGCGCGTCGCGAATGCCTGA

Upstream 100 bases:

>100_bases
ACGTTCGAAATGTCGCGAGGTGGCATGCGACTTGCCTGATTCGGCGGGAATGCCGTTTTTCCCGCTCGCCGGGCAATCTG
ATACAGGAGGGTAAGCCGTA

Downstream 100 bases:

>100_bases
GCCGCGCGTCGGCGCGCACGCGGGCGGGCTCGACGCCGATGCGGCGCTCGCCCGCTTCTTCGTGATCACGGGCGGGCCCG
GCTCGGGCAAGAGCACGCTG

Product: alpha,alpha-trehalose-phosphate synthase (UDP-forming)

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSRLIVVSNRVAAGQDARPTAGGLAVGVLDALKETGGVWFGWNGEIAGAPEEPVIERDGNVTYATVGLTRRDYDQYYRGF
SNATLWPVFHYRGDLARFDRQEYAGYLRVNCALAKQLCALVQPDDIIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPS
PEVLRTVPPHEELMKFMCAYDVIGLQTESDKQAFVDYIERRGLGTSSEDGILHAHGRVVKVAAYPIGIYPDAIGKAAIEY
GSRKAVKALRDTMRERKLVISVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPPTRSDVQTYQRIRQTLEGEAG
RINGRFAQLDWTPIQYLNRKYERNLLMALFRLSQVGYVTPLRDGMNLVAKEYVASQDPNDPGVLVLSEFAGAAAELPGAL
LVNPFDLSQMAESLERALAMPLEERQARHAENIARLRKNDLSVWRDSFLTDLRSVATAASVTQRAGRRVANA

Sequences:

>Translated_472_residues
MSRLIVVSNRVAAGQDARPTAGGLAVGVLDALKETGGVWFGWNGEIAGAPEEPVIERDGNVTYATVGLTRRDYDQYYRGF
SNATLWPVFHYRGDLARFDRQEYAGYLRVNCALAKQLCALVQPDDIIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPS
PEVLRTVPPHEELMKFMCAYDVIGLQTESDKQAFVDYIERRGLGTSSEDGILHAHGRVVKVAAYPIGIYPDAIGKAAIEY
GSRKAVKALRDTMRERKLVISVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPPTRSDVQTYQRIRQTLEGEAG
RINGRFAQLDWTPIQYLNRKYERNLLMALFRLSQVGYVTPLRDGMNLVAKEYVASQDPNDPGVLVLSEFAGAAAELPGAL
LVNPFDLSQMAESLERALAMPLEERQARHAENIARLRKNDLSVWRDSFLTDLRSVATAASVTQRAGRRVANA
>Mature_471_residues
SRLIVVSNRVAAGQDARPTAGGLAVGVLDALKETGGVWFGWNGEIAGAPEEPVIERDGNVTYATVGLTRRDYDQYYRGFS
NATLWPVFHYRGDLARFDRQEYAGYLRVNCALAKQLCALVQPDDIIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSP
EVLRTVPPHEELMKFMCAYDVIGLQTESDKQAFVDYIERRGLGTSSEDGILHAHGRVVKVAAYPIGIYPDAIGKAAIEYG
SRKAVKALRDTMRERKLVISVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPPTRSDVQTYQRIRQTLEGEAGR
INGRFAQLDWTPIQYLNRKYERNLLMALFRLSQVGYVTPLRDGMNLVAKEYVASQDPNDPGVLVLSEFAGAAAELPGALL
VNPFDLSQMAESLERALAMPLEERQARHAENIARLRKNDLSVWRDSFLTDLRSVATAASVTQRAGRRVANA

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=465, Percent_Identity=52.0430107526882, Blast_Score=488, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI71987012, Length=435, Percent_Identity=27.5862068965517, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115533558, Length=419, Percent_Identity=28.8782816229117, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115533560, Length=419, Percent_Identity=28.8782816229117, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319602, Length=466, Percent_Identity=33.6909871244635, Blast_Score=286, Evalue=6e-78,
Organism=Saccharomyces cerevisiae, GI6320279, Length=421, Percent_Identity=29.2161520190024, Blast_Score=184, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6323537, Length=436, Percent_Identity=27.9816513761468, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6323917, Length=374, Percent_Identity=28.8770053475936, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI19920676, Length=485, Percent_Identity=36.4948453608247, Blast_Score=284, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 52777; Mature: 52646

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIVVSNRVAAGQDARPTAGGLAVGVLDALKETGGVWFGWNGEIAGAPEEPVIERDGN
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEECCCC
VTYATVGLTRRDYDQYYRGFSNATLWPVFHYRGDLARFDRQEYAGYLRVNCALAKQLCAL
EEEEEECCCHHHHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHCCEEEEHHHHHHHHHHH
VQPDDIIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPEVLRTVPPHEELMKFMCAY
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHH
DVIGLQTESDKQAFVDYIERRGLGTSSEDGILHAHGRVVKVAAYPIGIYPDAIGKAAIEY
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEEECCCCHHHHHHHHHHH
GSRKAVKALRDTMRERKLVISVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPP
CCHHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
TRSDVQTYQRIRQTLEGEAGRINGRFAQLDWTPIQYLNRKYERNLLMALFRLSQVGYVTP
CHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LRDGMNLVAKEYVASQDPNDPGVLVLSEFAGAAAELPGALLVNPFDLSQMAESLERALAM
CHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCHHHHCCCCEEECCCCHHHHHHHHHHHHCC
PLEERQARHAENIARLRKNDLSVWRDSFLTDLRSVATAASVTQRAGRRVANA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRLIVVSNRVAAGQDARPTAGGLAVGVLDALKETGGVWFGWNGEIAGAPEEPVIERDGN
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEECCCC
VTYATVGLTRRDYDQYYRGFSNATLWPVFHYRGDLARFDRQEYAGYLRVNCALAKQLCAL
EEEEEECCCHHHHHHHHCCCCCCEEEEEHHHCCCHHHHHHHHHCCEEEEHHHHHHHHHHH
VQPDDIIWVHDYHLLPFAHCLRELGVKNPIGFFLHIPFPSPEVLRTVPPHEELMKFMCAY
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHCCCCHHHHHHHHHHH
DVIGLQTESDKQAFVDYIERRGLGTSSEDGILHAHGRVVKVAAYPIGIYPDAIGKAAIEY
HHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEEEEECCCCHHHHHHHHHHH
GSRKAVKALRDTMRERKLVISVDRLDYSKGLVERFQAFERMLANAPGWQGRVSLVQIAPP
CCHHHHHHHHHHHHHCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
TRSDVQTYQRIRQTLEGEAGRINGRFAQLDWTPIQYLNRKYERNLLMALFRLSQVGYVTP
CHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LRDGMNLVAKEYVASQDPNDPGVLVLSEFAGAAAELPGALLVNPFDLSQMAESLERALAM
CHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCHHHHCCCCEEECCCCHHHHHHHHHHHHCC
PLEERQARHAENIARLRKNDLSVWRDSFLTDLRSVATAASVTQRAGRRVANA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA