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The map label for this gene is rfaD [H]

Identifier: 126453539

GI number: 126453539

Start: 2881190

End: 2882182

Strand: Reverse

Name: rfaD [H]

Synonym: BURPS1106A_2939

Alternate gene names: 126453539

Gene position: 2882182-2881190 (Counterclockwise)

Preceding gene: 126454168

Following gene: 126452906

Centisome position: 72.26

GC content: 63.95

Gene sequence:

>993_bases
ATGACCCTCATCGTTACCGGCGCGGCCGGCTTCATCGGCGCGAACATCGTCAAGGCGCTGAACGAGCGCGGCGAGACGCG
CATCATCGCGGTCGACAACCTGACGCGCGCGGACAAGTTCAAGAATCTCGTCGATTGCGAGATCGACGACTATCTCGACA
AGACCGAGTTCGTCGAGCGCTTCGCGCGCGGCGATTTCGGCAAGGTGCGCGCGGTGTTTCATGAAGGCGCCTGCTCGGAC
ACGATGGAAACCGACGGCCGCTACATGATGGACAACAACTTCCGCTACAGCCGCGCGGTGCTCGACGCGTGCCTCGCGCA
GGGCACGCAGTTCCTGTATGCGTCGTCGGCCGCGATCTACGGCGGCTCGAGCCGCTTCGTCGAGGCGCGCGAGTTCGAGG
CGCCGCTCAATGTGTACGGCTATTCGAAGTTCCTGTTCGATCAGGTGATCCGCCGCGTGATGCCGAGCGCGAAGAGCCAG
ATCGCGGGCTTCCGCTATTTCAACGTGTACGGGCCGCGCGAGTCGCACAAGGGGCGCATGGCGTCGGTTGCGTTCCACAA
CTTCAACCAGTTTCGCGCCGAGGGCAAGGTCAAGCTCTTCGGCGAGTACAACGGCTATGGCCCGGGCGAGCAGACGCGCG
ATTTCGTGTCGGTCGAGGACGTCGCGAAGGTGAACCTGCATTTCTTCGATCACCCGCAGAAGTCGGGCATCTTCAATCTC
GGTACTGGCCGCGCGCAGCCGTTCAACGACATCGCGACGACGGTCGTCAACACGCTGCGCGCGCTCGAAGGCCAGCCCGC
GCTCACGCTTGCTGAGCAGGTCGAGCAGGGGCTCGTCGAATACGTGCCGTTCCCGGACGCGCTGCGCGGCAAGTACCAGT
GCTTCACGCAAGCCGATCAGACGAAGCTGCGCGCGGCCGGCTACGACGCGCCGTTCCTGACGGTGCAGGAAGGCGTCGAT
CGCTACGTTCGTTGGCTGTTCGGCCAGCTGTAA

Upstream 100 bases:

>100_bases
CTCGGCACCGCGACCGTCGAGTACGACGAACTGTTTCATTGAACGACAGCGGCGCGCGCCGCCCGCGCGCCGTACGCATA
CTCTCATCGGCAGAACGATC

Downstream 100 bases:

>100_bases
GCGGCGCGCGCGCCGCCTTAGACTGGGTCTCACGGTCGGCAGCCGCCGGCCGTTTTTTCACGGAGATCCAGATGCTGAAG
AAACTTCTCGCGACGGCCGC

Product: ADP-L-glycero-D-manno-heptose-6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSD
TMETDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIYGGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQ
IAGFRYFNVYGPRESHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNL
GTGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVD
RYVRWLFGQL

Sequences:

>Translated_330_residues
MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSD
TMETDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIYGGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQ
IAGFRYFNVYGPRESHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNL
GTGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVD
RYVRWLFGQL
>Mature_329_residues
TLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSDT
METDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIYGGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQI
AGFRYFNVYGPRESHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNLG
TGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDR
YVRWLFGQL

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=326, Percent_Identity=57.361963190184, Blast_Score=355, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI71982035, Length=277, Percent_Identity=25.6317689530686, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 37046; Mature: 36915

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVER
CEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCHHHHCCHHHHHHH
FARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIY
HHCCCHHHHHHHHHCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCEEEE
GGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQIAGFRYFNVYGPRESHKGRM
CCCCCCEEHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEEECCCCCCCCCE
ASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNL
EEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCHHHHHEEEEEEECCCCCCCEEEC
GTGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQ
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCHHH
TKLRAAGYDAPFLTVQEGVDRYVRWLFGQL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVER
EEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCHHHHCCHHHHHHH
FARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGTQFLYASSAAIY
HHCCCHHHHHHHHHCCCCCCCHHCCCCEEECCCCHHHHHHHHHHHHCCCCEEEECCEEEE
GGSSRFVEAREFEAPLNVYGYSKFLFDQVIRRVMPSAKSQIAGFRYFNVYGPRESHKGRM
CCCCCCEEHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEEEECCCCCCCCCE
ASVAFHNFNQFRAEGKVKLFGEYNGYGPGEQTRDFVSVEDVAKVNLHFFDHPQKSGIFNL
EEHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCHHHHHEEEEEEECCCCCCCEEEC
GTGRAQPFNDIATTVVNTLRALEGQPALTLAEQVEQGLVEYVPFPDALRGKYQCFTQADQ
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHCHHH
TKLRAAGYDAPFLTVQEGVDRYVRWLFGQL
HHHHHCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA