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The map label for this gene is cysC [H]

Identifier: 126453354

GI number: 126453354

Start: 2038389

End: 2039156

Strand: Reverse

Name: cysC [H]

Synonym: BURPS1106A_2056

Alternate gene names: 126453354

Gene position: 2039156-2038389 (Counterclockwise)

Preceding gene: 126451445

Following gene: 126454435

Centisome position: 51.13

GC content: 61.07

Gene sequence:

>768_bases
ATGACCTCGATGTCGCTCCTCGCTGCCGTTTATAGCGGCCGTCGCGAGGTGTCGATTGACGGATGCCATGAGGTGCAAAA
CATTGCCGTTGCCGCGGCGCTTGACGGCGGTCAAGCGCCGCCATCGGCGCACGGCGCCGTGCAATTCACTGACAGGAAGC
TTATGGACAAGTTACATGCGGAGCACAACGTCGAATGGCAGACGACGTCCGTCAGTCGGCGTGATCGTGAGTCGCGGCAG
GCGCACGGCGCGCTTGCAGTCTGGCTAACGGGCCTTCCCGGAGCTGGAAAGTCGACACTGGCGATCGAGGCGGAACGATG
CCTCCATCAAGCCGGGAAGCGGACTTATGTTCTGGATGGTGACAATCTTCGGCACGGACTGTGTCGCGACCTGGGATTCT
CCGCGGACGATCGCGCGGAAAACATTCGCCGCGCGGGCGAAGTGGCGCGACTGTTCGTCGACGCTGGCGTCATTGTGCTG
TCGGCCTTCATTTCTCCATTCCGATTCGATCGTGCGAAGGTTCGTGCACTGTTCGACGCGGGCGACTTCATCGAAGTGTA
CTGCGACTGCGATCCGCGGATTTGCGAAATCCGGGACGTCAAAGGCTTGTACAGAAGGGCGCGTGCGGGGCTGATTTCCG
AGTTCACCGGCATCTCCTCTCCTTACGAGCCGCCGCGGCATCCTGACGTCTACGTCAATACTGGCAAGGAATCGCTGGAT
GCATGCGTCGACAGGATCGTCCGCCGCGTGCTCCATTCGCTGCGCTAG

Upstream 100 bases:

>100_bases
GCGCCGACGCTTCGGATTGTGGTTCGGGCCGCCCTAGTGACTGCCCTGCCTGGTTTTCGACTTCGGCGCGGTGACATCCA
TCAAATTGAGGATGACGGGC

Downstream 100 bases:

>100_bases
TTATGATTAAGTTAGCTAAGCTGATGTGGCCGGGAGATCTGAGGAAGGCCACTTTGCAGCCGGTCCAGGATGAACAGCGT
GTGGCTCGATGCGGCCAATC

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTSMSLLAAVYSGRREVSIDGCHEVQNIAVAAALDGGQAPPSAHGAVQFTDRKLMDKLHAEHNVEWQTTSVSRRDRESRQ
AHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDGDNLRHGLCRDLGFSADDRAENIRRAGEVARLFVDAGVIVL
SAFISPFRFDRAKVRALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISEFTGISSPYEPPRHPDVYVNTGKESLD
ACVDRIVRRVLHSLR

Sequences:

>Translated_255_residues
MTSMSLLAAVYSGRREVSIDGCHEVQNIAVAAALDGGQAPPSAHGAVQFTDRKLMDKLHAEHNVEWQTTSVSRRDRESRQ
AHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDGDNLRHGLCRDLGFSADDRAENIRRAGEVARLFVDAGVIVL
SAFISPFRFDRAKVRALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISEFTGISSPYEPPRHPDVYVNTGKESLD
ACVDRIVRRVLHSLR
>Mature_254_residues
TSMSLLAAVYSGRREVSIDGCHEVQNIAVAAALDGGQAPPSAHGAVQFTDRKLMDKLHAEHNVEWQTTSVSRRDRESRQA
HGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDGDNLRHGLCRDLGFSADDRAENIRRAGEVARLFVDAGVIVLS
AFISPFRFDRAKVRALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISEFTGISSPYEPPRHPDVYVNTGKESLDA
CVDRIVRRVLHSLR

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI62912492, Length=191, Percent_Identity=47.6439790575916, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI34447231, Length=191, Percent_Identity=47.6439790575916, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI46094058, Length=191, Percent_Identity=45.5497382198953, Blast_Score=168, Evalue=5e-42,
Organism=Escherichia coli, GI1789107, Length=198, Percent_Identity=50.5050505050505, Blast_Score=193, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17542422, Length=191, Percent_Identity=45.5497382198953, Blast_Score=183, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6322852, Length=191, Percent_Identity=43.455497382199, Blast_Score=170, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24667032, Length=196, Percent_Identity=44.8979591836735, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667028, Length=196, Percent_Identity=44.8979591836735, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667036, Length=196, Percent_Identity=44.8979591836735, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667040, Length=196, Percent_Identity=44.8979591836735, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI116007838, Length=196, Percent_Identity=44.8979591836735, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667044, Length=196, Percent_Identity=44.8979591836735, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 28159; Mature: 28028

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSMSLLAAVYSGRREVSIDGCHEVQNIAVAAALDGGQAPPSAHGAVQFTDRKLMDKLHA
CCHHHHHHHHHCCCCEEECCCHHHHHHHEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHH
EHNVEWQTTSVSRRDRESRQAHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDG
HCCCCEEECCCHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEHHHHHHHHCCCEEEEECC
DNLRHGLCRDLGFSADDRAENIRRAGEVARLFVDAGVIVLSAFISPFRFDRAKVRALFDA
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GDFIEVYCDCDPRICEIRDVKGLYRRARAGLISEFTGISSPYEPPRHPDVYVNTGKESLD
CCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHH
ACVDRIVRRVLHSLR
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSMSLLAAVYSGRREVSIDGCHEVQNIAVAAALDGGQAPPSAHGAVQFTDRKLMDKLHA
CHHHHHHHHHCCCCEEECCCHHHHHHHEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHH
EHNVEWQTTSVSRRDRESRQAHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDG
HCCCCEEECCCHHHHHHHHHHCCEEEEEEECCCCCCCCEEEEHHHHHHHHCCCEEEEECC
DNLRHGLCRDLGFSADDRAENIRRAGEVARLFVDAGVIVLSAFISPFRFDRAKVRALFDA
CCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
GDFIEVYCDCDPRICEIRDVKGLYRRARAGLISEFTGISSPYEPPRHPDVYVNTGKESLD
CCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCHHHHH
ACVDRIVRRVLHSLR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]