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The map label for this gene is coaE [H]

Identifier: 126453294

GI number: 126453294

Start: 3437260

End: 3437871

Strand: Direct

Name: coaE [H]

Synonym: BURPS1106A_3534

Alternate gene names: 126453294

Gene position: 3437260-3437871 (Clockwise)

Preceding gene: 126455285

Following gene: 126452426

Centisome position: 86.18

GC content: 67.16

Gene sequence:

>612_bases
ATGTTCTCGGTGGGATTGACGGGCGGCATCGGTAGCGGCAAGACGACCGTGGCCGATTTGTTCGGTAAGCTCGGCGCGAC
AATCGTCGATACCGATCTGATCGCGCACCGCATCACCGCGCCGCAAGGCCTCGCGATGCCACTCATCGCGCGCGAGTTCG
GCGCGGAATTCGTCGCGGCCGACGGCTCGCTCGATCGCGCGAAGATGCGCGCGCTGGTCTTCAGCGACGAATCCGCGCGC
AAACGGCTCGAAGCGATCACGCATCCGCTGATCCGCGAAGAAACCGAGCGCGAAGCGCGTACGGCCCAAGGCGCATACAT
CGTATTCGTCGTGCCGCTGCTCGTCGAATCGGGCACATGGAAGACGCGCGTCGACCGCGTGCTCGTCGTCGACTGCGACG
TCGAGACGCAAATCGCACGCGTGACGGCCCGCAACGGCTTCACCCGCGCGCAGGTGGAGGCGATCGTCGCGCGGCAGGCG
TCGCGCGACGCGCGTCTCGCCGCCGCCGACGACGTGATCGCCAACGACAATGCGTCCGTCGCCGAGCTCGCCGCCGAAGT
CGCCGCACTGCACCAACGCTATCTTGAATGCGCGGCCGCCGCGCGGAATTGA

Upstream 100 bases:

>100_bases
CTTCGAGGAACCGTTGCCATTCGGCCCGTTCCTCGCGGCGGGCGGCGCCGCGACCCTCTTTTTCGGCACGCCGTTCTACC
TGCTGCTCGGAGGCTGAACC

Downstream 100 bases:

>100_bases
CAAGCTTGCGGCACGCACGTTGCGTGCCGTGCACGCAACCATGCGGCCCATCGTCAGCGCCGAAAAATGGCGCGATTGCT
AGGGTAGACCGTGGGCATTA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAADGSLDRAKMRALVFSDESAR
KRLEAITHPLIREETEREARTAQGAYIVFVVPLLVESGTWKTRVDRVLVVDCDVETQIARVTARNGFTRAQVEAIVARQA
SRDARLAAADDVIANDNASVAELAAEVAALHQRYLECAAAARN

Sequences:

>Translated_203_residues
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAADGSLDRAKMRALVFSDESAR
KRLEAITHPLIREETEREARTAQGAYIVFVVPLLVESGTWKTRVDRVLVVDCDVETQIARVTARNGFTRAQVEAIVARQA
SRDARLAAADDVIANDNASVAELAAEVAALHQRYLECAAAARN
>Mature_203_residues
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAADGSLDRAKMRALVFSDESAR
KRLEAITHPLIREETEREARTAQGAYIVFVVPLLVESGTWKTRVDRVLVVDCDVETQIARVTARNGFTRAQVEAIVARQA
SRDARLAAADDVIANDNASVAELAAEVAALHQRYLECAAAARN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=178, Percent_Identity=35.3932584269663, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI191252795, Length=178, Percent_Identity=35.3932584269663, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI110227607, Length=166, Percent_Identity=30.1204819277108, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227605, Length=166, Percent_Identity=30.1204819277108, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227603, Length=166, Percent_Identity=30.1204819277108, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227601, Length=166, Percent_Identity=30.1204819277108, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI205277394, Length=166, Percent_Identity=30.1204819277108, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=46.969696969697, Blast_Score=171, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17554944, Length=192, Percent_Identity=35.4166666666667, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320402, Length=205, Percent_Identity=30.7317073170732, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=32.1243523316062, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658602, Length=177, Percent_Identity=28.8135593220339, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21733; Mature: 21733

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAA
CCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEC
DGSLDRAKMRALVFSDESARKRLEAITHPLIREETEREARTAQGAYIVFVVPLLVESGTW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCC
KTRVDRVLVVDCDVETQIARVTARNGFTRAQVEAIVARQASRDARLAAADDVIANDNASV
HHHHCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHCCCCCHH
AELAAEVAALHQRYLECAAAARN
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFSVGLTGGIGSGKTTVADLFGKLGATIVDTDLIAHRITAPQGLAMPLIAREFGAEFVAA
CCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEC
DGSLDRAKMRALVFSDESARKRLEAITHPLIREETEREARTAQGAYIVFVVPLLVESGTW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCC
KTRVDRVLVVDCDVETQIARVTARNGFTRAQVEAIVARQASRDARLAAADDVIANDNASV
HHHHCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCCHHCCCCCHH
AELAAEVAALHQRYLECAAAARN
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA