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The map label for this gene is ung [H]

Identifier: 126453114

GI number: 126453114

Start: 3495320

End: 3496108

Strand: Direct

Name: ung [H]

Synonym: BURPS1106A_3588

Alternate gene names: 126453114

Gene position: 3495320-3496108 (Clockwise)

Preceding gene: 126451971

Following gene: 126453983

Centisome position: 87.64

GC content: 69.84

Gene sequence:

>789_bases
ATGCCGCAACCCTCGCTGTTCGACGATCATACGCCGCCCGCGCCGCCCGCAGTGCAAGGCGGCGCATCCGCGCTCACCCT
GGAATCGCAATTCGACGCGCTGCCGCCCGACTGGCGCGCGATCGTCGAGCCGTTCGTCGCGAGCGACGCGTATGCGCCGC
TCTGCCGCTTCGTCGACGGCGAGCGCGCGGCGGGCAAAGCGATTTATCCGGCGGACGTATTCCGCGCACTGCGGCTCACG
CACCCGGACGACGTGAAGGTCGTGATTCTCGGCCAGGACCCCTACCACGGCGAGGATCGCGGCATCCCGCAGGCGCACGG
GCTCGCGTTCTCGGTACCGCCCGGCGTGCGGCCGCCGCCGTCGCTGCGCAACATCTTCAAGGAAATCTCGGCCGACTTCG
GCTACGAGACGCCCCGCCACGGCTGCCTGGACACATGGGCGCGCCAGGGCGTGCTGCTGCTCAACACGGTGTTGACGGTC
GAGCGCGCGGCGGCGGCCAGCCATGCGAAGCGCGGCTGGGAGAAATGCACCGACACGCTGATCCACGAACTCGCGACGCG
CCACCGGCACCTCGTGTTCATGCTATGGGGCGCGCACGCGCAGGCGAAACGCGCGCTGTTCGACGCGCGTGAGCATTGCG
TGCTCGAAGCGCCGCATCCGTCGCCGCTGTCCGCGCACCGCGGCTTTCTCGGCTGTCGTCATTTCGCGCTCGCGAACGAC
TATCTCGTGCAGCACGGGCGCGCGCCGATCGACTGGCGGCTGCCCGACGAGGCCGAAACGCTTGCCTGA

Upstream 100 bases:

>100_bases
ACCTGAGCAAGGCGCAGCGCGGCTACCGGCTGCGCGGCGGCGATCTGCGCGCCGACTGACCACCCCTTTGCGCATGACCA
AGCCCTCTTCTCCCCGCCCG

Downstream 100 bases:

>100_bases
CGCGTGACCATGGCGGATGGCGGCGCAACCGCCCCCCGCCTCCCGACTCCCGCCCGCGCGCCCCCGCCGCGCGATCGCGC
GCGACAGGCGGCGAGCGCGC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MPQPSLFDDHTPPAPPAVQGGASALTLESQFDALPPDWRAIVEPFVASDAYAPLCRFVDGERAAGKAIYPADVFRALRLT
HPDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPPSLRNIFKEISADFGYETPRHGCLDTWARQGVLLLNTVLTV
ERAAAASHAKRGWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDAREHCVLEAPHPSPLSAHRGFLGCRHFALAND
YLVQHGRAPIDWRLPDEAETLA

Sequences:

>Translated_262_residues
MPQPSLFDDHTPPAPPAVQGGASALTLESQFDALPPDWRAIVEPFVASDAYAPLCRFVDGERAAGKAIYPADVFRALRLT
HPDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPPSLRNIFKEISADFGYETPRHGCLDTWARQGVLLLNTVLTV
ERAAAASHAKRGWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDAREHCVLEAPHPSPLSAHRGFLGCRHFALAND
YLVQHGRAPIDWRLPDEAETLA
>Mature_261_residues
PQPSLFDDHTPPAPPAVQGGASALTLESQFDALPPDWRAIVEPFVASDAYAPLCRFVDGERAAGKAIYPADVFRALRLTH
PDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPPSLRNIFKEISADFGYETPRHGCLDTWARQGVLLLNTVLTVE
RAAAASHAKRGWEKCTDTLIHELATRHRHLVFMLWGAHAQAKRALFDAREHCVLEAPHPSPLSAHRGFLGCRHFALANDY
LVQHGRAPIDWRLPDEAETLA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=220, Percent_Identity=47.7272727272727, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI6224979, Length=220, Percent_Identity=47.7272727272727, Blast_Score=194, Evalue=6e-50,
Organism=Escherichia coli, GI1788934, Length=208, Percent_Identity=59.1346153846154, Blast_Score=229, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17556304, Length=219, Percent_Identity=42.9223744292237, Blast_Score=190, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6323620, Length=222, Percent_Identity=42.7927927927928, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 28863; Mature: 28732

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPSLFDDHTPPAPPAVQGGASALTLESQFDALPPDWRAIVEPFVASDAYAPLCRFVDG
CCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
ERAAGKAIYPADVFRALRLTHPDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPP
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCH
SLRNIFKEISADFGYETPRHGCLDTWARQGVLLLNTVLTVERAAAASHAKRGWEKCTDTL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHELATRHRHLVFMLWGAHAQAKRALFDAREHCVLEAPHPSPLSAHRGFLGCRHFALAND
HHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
YLVQHGRAPIDWRLPDEAETLA
HHHHCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
PQPSLFDDHTPPAPPAVQGGASALTLESQFDALPPDWRAIVEPFVASDAYAPLCRFVDG
CCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHCCC
ERAAGKAIYPADVFRALRLTHPDDVKVVILGQDPYHGEDRGIPQAHGLAFSVPPGVRPPP
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHCCEEEECCCCCCCCH
SLRNIFKEISADFGYETPRHGCLDTWARQGVLLLNTVLTVERAAAASHAKRGWEKCTDTL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IHELATRHRHLVFMLWGAHAQAKRALFDAREHCVLEAPHPSPLSAHRGFLGCRHFALAND
HHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHH
YLVQHGRAPIDWRLPDEAETLA
HHHHCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA