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The map label for this gene is hmp [H]

Identifier: 126453088

GI number: 126453088

Start: 3249671

End: 3250870

Strand: Reverse

Name: hmp [H]

Synonym: BURPS1106A_3326

Alternate gene names: 126453088

Gene position: 3250870-3249671 (Counterclockwise)

Preceding gene: 126453287

Following gene: 126454171

Centisome position: 81.51

GC content: 68.08

Gene sequence:

>1200_bases
ATGACCGCCGAGCAAATGGCCCGAGTGAAAGCGACCGCCCCGGTTCTCGCGGAGCACGGCGCGACGATCACGAAGCACTT
TTATCAGCGGATGTTCGGGCGCCACCCCGAGCTGAAGAACGTTTTCAACCAGACGCACCAGAAGACGGGCAGCCAGCCGG
AGACGCTCGCGAAGGCGGTCTACGCATACGCGGCGAACATCGACAATCTCGGCGCGCTCGGCGGCGCCGTGTCGCGGATC
GCGCACAAGCACGCGAGCCTGAACATCCGGCCGGAGCACTACCCGATCGTCGGCGAGAACCTGCTCGCCTCGATCGTCGA
GGTGCTCGGCGACGCGGTGGACGCGGACACGCTCGAAGCGTGGCGCATCGCGTACGGCCAGCTCGCCGCGATCCTGATCG
GCGCGGAGGCGAACCTGTACGAGAACGCCGCATGGAGCGGCTTCCGCCCGTTCAAGGTCGCGAAGAAGGTGCGCGAGAGC
GACGAGATCACGTCGTTCTACCTGACGCCCGCCGACGGCGGCGCGGCGCCCGGGTTCGAGCCGGGCCAGTACATCTCGGT
GAAGCGTTTCGTCGGCGACATGGGCGTCGATCAGCCGCGTCAGTACAGCCTGTCCGACGCGCCGCACGGCAAGTGGCTGC
GCATCTCGGTCAAGCGCGAGGCGGGGCACAGCGAGGCGGTGCCGGCGGGCAAGGTGTCGACGCTGATGCACGACGGCGTC
GACGTCGATTCGGTCGTCGAAGTCACCGCGCCGATGGGCGATTTCACGCTGAACCGCCATGCGGCGACGCCCGTCGTGCT
GATTTCGGGCGGCGTCGGGATCACGCCGATGATGTCGATGGCGTCGACGCTCGTCGCAGCGGGCAGCGAGCGCGAAGTGC
GTTTCCTGCACGCGTGCCGCGCGGCGAACGTGCATGCGTTCCGCGACTGGCTGAACGACACGACGGACGCGCATCCGAAC
GTGAAGCGCGCGGTGTTCTACGAGGTGGTCGGCCCGAACGACCGCGTGGGCGTCGATCACGACCACGAAGGCCGGATCAC
GCCGGCTGCGCTCGAGCGCCACGCGCTCGTGCCGGACGCCGATTACTACATCTGCGGGCCGATCGCGTTCATGAAGCAGC
AGCGCGACGCGCTCGTTGCGCTCGGCGTCGCGCCGGAGCGCGTGCAGACGGAAATCTTCGGTTCGGGCGCGCTCGAATGA

Upstream 100 bases:

>100_bases
GGCCCGTTATGGCGAGGTGCGACAATTTGACCGCCGGAGGTGCGCTCATAAAGATGTATCGTTTGCGAATGTTTAACGGA
GGAATACTTTCATGACGCAG

Downstream 100 bases:

>100_bases
CGAAGCGCCGGCGAACGACACGGGTTCGCTGAAGCGAAACGGCAAAGCCCGGCGCCATGCGCCGGGCTTTTTCTTGGGCG
AGGGCCGCGCGGGAGCCGGA

Product: flavohemoprotein

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAVSRI
AHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVRES
DEITSFYLTPADGGAAPGFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMHDGV
DVDSVVEVTAPMGDFTLNRHAATPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACRAANVHAFRDWLNDTTDAHPN
VKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE

Sequences:

>Translated_399_residues
MTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAVSRI
AHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVRES
DEITSFYLTPADGGAAPGFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMHDGV
DVDSVVEVTAPMGDFTLNRHAATPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACRAANVHAFRDWLNDTTDAHPN
VKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE
>Mature_398_residues
TAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAVYAYAANIDNLGALGGAVSRIA
HKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVRESD
EITSFYLTPADGGAAPGFEPGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMHDGVD
VDSVVEVTAPMGDFTLNRHAATPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACRAANVHAFRDWLNDTTDAHPNV
KRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDADYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=399, Percent_Identity=42.6065162907268, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1787658, Length=258, Percent_Identity=25.968992248062, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321673, Length=405, Percent_Identity=37.037037037037, Blast_Score=237, Evalue=2e-63,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43165; Mature: 43034

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS01033 GLOBIN ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAV
CCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
YAYAANIDNLGALGGAVSRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEA
HHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
WRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVRESDEITSFYLTPADGGAAPGFE
HHHHHHHEEEEEECCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
PGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMHDGV
CCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCC
DVDSVVEVTAPMGDFTLNRHAATPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACR
CHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
AANVHAFRDWLNDTTDAHPNVKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDA
HCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
DYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE
CEEEECHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAEQMARVKATAPVLAEHGATITKHFYQRMFGRHPELKNVFNQTHQKTGSQPETLAKAV
CHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHH
YAYAANIDNLGALGGAVSRIAHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEA
HHHHCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
WRIAYGQLAAILIGAEANLYENAAWSGFRPFKVAKKVRESDEITSFYLTPADGGAAPGFE
HHHHHHHEEEEEECCCCCHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
PGQYISVKRFVGDMGVDQPRQYSLSDAPHGKWLRISVKREAGHSEAVPAGKVSTLMHDGV
CCCEEHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCC
DVDSVVEVTAPMGDFTLNRHAATPVVLISGGVGITPMMSMASTLVAAGSEREVRFLHACR
CHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
AANVHAFRDWLNDTTDAHPNVKRAVFYEVVGPNDRVGVDHDHEGRITPAALERHALVPDA
HCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
DYYICGPIAFMKQQRDALVALGVAPERVQTEIFGSGALE
CEEEECHHHHHHHHCCEEEEECCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]