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The map label for this gene is lpxK [H]

Identifier: 126453033

GI number: 126453033

Start: 913175

End: 914305

Strand: Reverse

Name: lpxK [H]

Synonym: BURPS1106A_0930

Alternate gene names: 126453033

Gene position: 914305-913175 (Counterclockwise)

Preceding gene: 126451813

Following gene: 126454062

Centisome position: 22.92

GC content: 73.65

Gene sequence:

>1131_bases
GTGCCGCCTTTCGAAGACCGCGCGGCCGCCCGCCGCCATCCGGAGAACCGTGTTGACGAATCCGTCCTCAATCGCGCCGC
GCGGCGTCCCGCGCATCGCGTCATGAGCGCTCGGCCGGGATTGCTCGCACGCGCCGAAGCGCGCCTCACCCGCGAGTGGC
AGCGCCGCGGCGCGCTCGCATGGGCGCTCGCGCCGTTCGCCTGCGCGTTCGGCGCGATCGCCGCGCTGCGCCGCGCCGCC
TATGCGCGCGGCTGGAAGGCGCGCGTCGATTGCGGCGTGCCCGTCGTCGTCGTCGGCAATGTGACGGTCGGCGGCACCGG
CAAGACGCCCACCGTGATCGCGCTCGTCGACGCGCTGCGCGCCGCGGGCTTCACGCCCGGCGTCGTATCGCGCGGCTACG
GCGCGAAGATCGCCGCGCCGACCGCGGTCACGGCCGCGTCGCCGCCGCAGCAGGCGGGCGACGAGCCGCTCCTGATCGCG
CGCCGCACGCTCGCGCCCGTGTGGGTGTGCCCGGACCGCGTCGCGGCCGTGCGCGCGCTGAAGGCCGCGCACCCCGAAGT
GGACGTCGTCGTCAGCGACGACGGCCTGCAGCACTACCGGCTCGCGCGCGCGGTCGAGATCGTCGTGTTCGACCATCGCC
TCGGCGGCAACGGCTTTCTGCTGCCGGCCGGGCCGCTGCGCGAGCCGTTGTCGCGCCGGCGCGACGCGACGCTCGTCAAC
GATCCGTACAGCCGCGCGCTGCCGCCGTGGCCCGATACGTTCGCGCTGTCGCTCGCGCCCGGCGACGCCTGGCATCTCGA
TCGACCGTCGCGGCGCAAGCCGCTCGCGCAATTCGCGGGCGAGCGCGTGCTCGCGGCCGCAGGCATCGGCGCGCCCGAGC
GCTTTTTCGCGACGCTGCGCGCGGCGGGCGTCGCGCCCGCGACGCGCGCGCTGCCCGATCACTACGCGTTCGCGACGAAC
CCGTTCGTCGACGATCATTTCGACGCGATCCTGATCACCGAGAAGGATGCAGTAAAATTGGGGACTTCGTGGCGCGACGC
CCGCATCTGGGTCGTCCCGGTCGAAGCCGCGCTCGATCCCCGCCTCATCGCTCTCGTTGTGGAGAAACTCCGTGGACGCA
CGTCTGCTTGA

Upstream 100 bases:

>100_bases
GTTATCCACAGGCGGCGCGGGCGCGCGACAGCGCCGCGGGTGCCGCGCGCCGCGCGTCGCGCGTCGCGCGACTTGCGGGC
CGTACGGCGGGCGCGCTAGA

Downstream 100 bases:

>100_bases
AATCCTCGTCTGCCCGATTTGCAAGGGTCCGCTCCACTATGATCGCGGCGCGCAGGAGCTCGTCTGCCATGCCGACAAGC
TCGCGTATCCGATTCGCGAC

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MPPFEDRAAARRHPENRVDESVLNRAARRPAHRVMSARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAA
YARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIA
RRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVN
DPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATN
PFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA

Sequences:

>Translated_376_residues
MPPFEDRAAARRHPENRVDESVLNRAARRPAHRVMSARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAA
YARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIA
RRTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVN
DPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATN
PFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA
>Mature_375_residues
PPFEDRAAARRHPENRVDESVLNRAARRPAHRVMSARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAAY
ARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIAR
RTLAPVWVCPDRVAAVRALKAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVND
PYSRALPPWPDTFALSLAPGDAWHLDRPSRRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATNP
FVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=324, Percent_Identity=44.1358024691358, Blast_Score=203, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 40472; Mature: 40341

Theoretical pI: Translated: 11.15; Mature: 11.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPFEDRAAARRHPENRVDESVLNRAARRPAHRVMSARPGLLARAEARLTREWQRRGALA
CCCCCHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
WALAPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALR
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECEEECCCCCCCHHHHHHHHHH
AAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIARRTLAPVWVCPDRVAAVRAL
HCCCCCHHHCCCCCCEECCCCEEECCCCHHHCCCCCEEEEHHHCCCEEECCHHHHHHHHH
KAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVN
HHCCCCEEEEECCCCHHHHHHHHEEEEEEEEEEECCCEEEECCCHHHHHHHHHCCCCEEC
DPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKPLAQFAGERVLAAAGIGAPERFFATLR
CCHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCHHHHHCCCCEEEECCCCCHHHHHHHHH
AAGVAPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDP
HHCCCCHHHCCCCCCEECCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEEEECCCCCH
RLIALVVEKLRGRTSA
HHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PPFEDRAAARRHPENRVDESVLNRAARRPAHRVMSARPGLLARAEARLTREWQRRGALA
CCCCHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHH
WALAPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALR
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECEEECCCCCCCHHHHHHHHHH
AAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIARRTLAPVWVCPDRVAAVRAL
HCCCCCHHHCCCCCCEECCCCEEECCCCHHHCCCCCEEEEHHHCCCEEECCHHHHHHHHH
KAAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVN
HHCCCCEEEEECCCCHHHHHHHHEEEEEEEEEEECCCEEEECCCHHHHHHHHHCCCCEEC
DPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKPLAQFAGERVLAAAGIGAPERFFATLR
CCHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCHHHHHCCCCEEEECCCCCHHHHHHHHH
AAGVAPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDP
HHCCCCHHHCCCCCCEECCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEEEECCCCCH
RLIALVVEKLRGRTSA
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA