Click here to switch to the map view.

The map label for this gene is lptD

Identifier: 126452995

GI number: 126452995

Start: 682440

End: 684803

Strand: Direct

Name: lptD

Synonym: BURPS1106A_0706

Alternate gene names: 126452995

Gene position: 682440-684803 (Clockwise)

Preceding gene: 126453233

Following gene: 226830776

Centisome position: 17.11

GC content: 66.58

Gene sequence:

>2364_bases
ATGCCGCCTAAAACGTTATTCCCGCTCGTCCCAGCTTGCGATGCCGCGCCGCGCAAAAAACGGCTCGCGGTCGCGCTTTT
GGCCGTACCGGGCCTCGTGCCGGCGGTGTCGCAGGCCCAGCTGTCGGGCGCCGCTGCCGAGCCGCAGGCGTTCGGCTCGC
CGTGGGACCTGCGCCTCGCGCCGCAGCTCGACGAGCATCCGCAAAAGCAGGGCGGCAAGCCCGCGACGTTCGTGCTCGCC
GATCATACGAACGGCACCGCCGAGCAGGATCTCGCCGCGAAGGGGGCGGCCGAGATCCGCCGCGGCAACGCGGCCGTCAA
GGCGGATGCGATCCACTACGATCAGGACACCGACATGGCCGACGCGTACGGCAAGGTCACGGTGGCCAACGGCGGCACGA
CGTTCTCGGGGCCCGAGGCGCATCTGAAGGTCGAGGCGAATCAGGGTTTCATGACGACGCCGAAGTACCGCTTCACGGCG
ACGGGCGGCACGGGCAGCGCCGAGCGGGTGCAGCTTCTCGACAGCGAGCGCTCGGTGTTCACGAACGGCACGTACACGGG
CTGCCAGTGCTCGACGAATCCGGCGTGGTACATCAAGGGCAGCGAGTTCGATTTCGATACGGGCGCCGACGAGGGCGTCG
CGCGCAACGGCGTGCTGTTCTTCCAGGGCGTGCCGCTCTTCGGCAGCCCCTGGCTCACGTTCCCGTTGTCGGGCGATCGG
CGCAGCGGCTTCCTGCCGCCGACGTTCTCGCCGTTCAGCTCGACGAACGGCTTCGAGTTGTCGCTGCCGTACTACTTCAA
CATCGCGCCGAACCGCGATCTGACGATCACGCCGCACATCATCTCGAAGCGCGGGATCTTCACGCAGGCGACGTTCCGCT
ATCTGTCGACGAACTACTCGGGCACGCTGACGGGTGAATACCTGCCGGACGACCGCGTCGCTCACCGCAACCGCTACGCG
ATTTTCTGGCAGCACCAGCAGAACTTCGGCAACGGCTTCGGCGGCTACGTTTACTACAACAAGGTCTCGGACAACCTGTA
TCCCGAAGAGCTCGGCTCGACGAACCAGTTCGTCAACGGGGTCCAGACCGTCTATCAGCAGGAAGCCGGCCTCACGTACA
ACAACGGGCCGTGGTCGGTGCTCGGCCGCTACCAGCACTGGCAGACGCTGCCGCCGTCGGCCGCGCCTTACGGGCGCGAG
CCGCAGTTGAACGTGAAGTACACGAAGTACAACGTCGGCGGCTTCGACTTCGGCGCGGAAGCCGATTATTCGCGCTTCCG
GATCACGACGGCGGACCAGCCGGAAGGCGACCGCGTGATGTTCAACCCGTACGTGTCGTACGGGTTGTACGGCCCCGGCT
ACTTCTTCGTGCCGAAGGCGCAGCTGCACATGGCGTCGTACGACCTGACGACGACGACGGGCGGCGTGCCCGGCCAGCCG
AAGCGCTTCACGTACTCGATCCCGACGCTCAGCCTCGACACCGGGCTCGTGTTCGACCGCTCGGTGCGCCTGTTCGGCCA
GGACTTCATCCAGACGCTGGAGCCGCGCCTGTTCTACGTGTACACGCCGTACCGGAACCAGTCGAACGCGCCGCTCTTCG
ACACGGCCGTGTCGGACTTCGGGCTCGCGGAAATCTTCACGCCGAACACGTTCGTCGGCAACGACCGGATCGCCGACGCG
AACCGCCTGACGGCCGCCCTCACGACCCGCTTCATCAATCCGACGACGGGCGACGAGCGCGCGCGCTTCGTGATCGCGCA
GCAGTATTACTTCACCGATCAGCGGGTGACGCTCCTGCCGACCGAGGCGCCCGCGACCGCGCGGCACTCGGACCTGATCC
TCGGCGCGTCGGTCAAGCTCGGCGCGGGTTTCGCGTCGGAGACGGCGTTCCAGTACAACGTCGACAACAACCAGCTCGTG
AAGTCGAGCGTGGGCTTCGGCTATAGCCCGGGCGAGCGGCGCGTGATCAACGTCGGCTACCGCTACACGCGGCAGAACCC
GACGCTCAGCAACGAGCCGATCAACCAGATCCTCATGTCCGCGCAATGGCCGCTCACGCGGCGGCTCTATGCGGTCGGCC
GTCTGAACTACGATCTCGCGAGCAGCCGGGTTGTCGACGGTCTCGTCGGCTTCCAGTACGATGCCGACTGCTGGGCGTTC
GGCGTCGGCGTCCAGCGGTACGCGAACGGCCTGAACTCGTCGGGGCAGCAGAATTCGTCGACCCGCGTGCTCGCGCAGCT
CGTGCTCAAGGGGCTGACGAGCATCGACAACGGGCTCGTGACCGCGTTCCGCGCCGGCGTGCAGGGCTACACGCCGCTGC
CGCCCGCGCCGGCGCCGCTGTCGCGCTTCAGTAATTACGATTAA

Upstream 100 bases:

>100_bases
CCCGTTTCCCCCGGTATGCGCGAAGCCGCAGTCACGGTTCGATTGCGCGGGCGCGGCATGTGGAGGCCGGGTTTGACAGG
GGCGATTCGCCGAACGATAG

Downstream 100 bases:

>100_bases
CCGCCGACGAGGCGTTCGCGGCGAGCGGCGTTTGCGCAGCCCGCTTTCAATGGAGTACCAGTGGCAATGAAGAAAACCCT
TCGCTTCGCGGCTGTCGCAT

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MPPKTLFPLVPACDAAPRKKRLAVALLAVPGLVPAVSQAQLSGAAAEPQAFGSPWDLRLAPQLDEHPQKQGGKPATFVLA
DHTNGTAEQDLAAKGAAEIRRGNAAVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYRFTA
TGGTGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIKGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGDR
RSGFLPPTFSPFSSTNGFELSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGTLTGEYLPDDRVAHRNRYA
IFWQHQQNFGNGFGGYVYYNKVSDNLYPEELGSTNQFVNGVQTVYQQEAGLTYNNGPWSVLGRYQHWQTLPPSAAPYGRE
PQLNVKYTKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHMASYDLTTTTGGVPGQP
KRFTYSIPTLSLDTGLVFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADA
NRLTAALTTRFINPTTGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLV
KSSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
GVGVQRYANGLNSSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD

Sequences:

>Translated_787_residues
MPPKTLFPLVPACDAAPRKKRLAVALLAVPGLVPAVSQAQLSGAAAEPQAFGSPWDLRLAPQLDEHPQKQGGKPATFVLA
DHTNGTAEQDLAAKGAAEIRRGNAAVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYRFTA
TGGTGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIKGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGDR
RSGFLPPTFSPFSSTNGFELSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGTLTGEYLPDDRVAHRNRYA
IFWQHQQNFGNGFGGYVYYNKVSDNLYPEELGSTNQFVNGVQTVYQQEAGLTYNNGPWSVLGRYQHWQTLPPSAAPYGRE
PQLNVKYTKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHMASYDLTTTTGGVPGQP
KRFTYSIPTLSLDTGLVFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADA
NRLTAALTTRFINPTTGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLV
KSSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
GVGVQRYANGLNSSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD
>Mature_786_residues
PPKTLFPLVPACDAAPRKKRLAVALLAVPGLVPAVSQAQLSGAAAEPQAFGSPWDLRLAPQLDEHPQKQGGKPATFVLAD
HTNGTAEQDLAAKGAAEIRRGNAAVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYRFTAT
GGTGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIKGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGDRR
SGFLPPTFSPFSSTNGFELSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGTLTGEYLPDDRVAHRNRYAI
FWQHQQNFGNGFGGYVYYNKVSDNLYPEELGSTNQFVNGVQTVYQQEAGLTYNNGPWSVLGRYQHWQTLPPSAAPYGREP
QLNVKYTKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHMASYDLTTTTGGVPGQPK
RFTYSIPTLSLDTGLVFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADAN
RLTAALTTRFINPTTGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVK
SSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAFG
VGVQRYANGLNSSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family

Homologues:

Organism=Escherichia coli, GI1786239, Length=774, Percent_Identity=27.7777777777778, Blast_Score=262, Evalue=7e-71,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): LPTD_BURMA (Q62MM5)

Other databases:

- EMBL:   CP000010
- RefSeq:   YP_102043.1
- ProteinModelPortal:   Q62MM5
- GeneID:   3089739
- GenomeReviews:   CP000010_GR
- KEGG:   bma:BMA0208
- TIGR:   BMA0208
- HOGENOM:   HBG701380
- OMA:   TPYYWNI
- PhylomeDB:   Q62MM5
- ProtClustDB:   CLSK896578
- BioCyc:   BMAL243160:BMA_0208-MONOMER
- HAMAP:   MF_01411
- InterPro:   IPR020889
- InterPro:   IPR007543

Pfam domain/function: PF04453 OstA_C

EC number: NA

Molecular weight: Translated: 86453; Mature: 86322

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPKTLFPLVPACDAAPRKKRLAVALLAVPGLVPAVSQAQLSGAAAEPQAFGSPWDLRLA
CCCCCCCCCCCCCCCCCCHHHEEEEEEHHCCCCCCHHHHHHCCCCCCCHHCCCCCCEEEC
PQLDEHPQKQGGKPATFVLADHTNGTAEQDLAAKGAAEIRRGNAAVKADAIHYDQDTDMA
CCCCCCHHHCCCCCEEEEEEECCCCCCHHHHHHCCHHHHHCCCCEEEEEEEECCCCCCHH
DAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYRFTATGGTGSAERVQLLDSERSVF
HCCCEEEEECCCCCCCCCCEEEEEECCCCEEECCCEEEEECCCCCCHHHEEEECCCCCEE
TNGTYTGCQCSTNPAWYIKGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGDR
ECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCC
RSGFLPPTFSPFSSTNGFELSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYS
CCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEECCHHHCCCCCCHHHHHHHHHCCCC
GTLTGEYLPDDRVAHRNRYAIFWQHQQNFGNGFGGYVYYNKVSDNLYPEELGSTNQFVNG
CEEECCCCCCCHHCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHCCCHHHHHHH
VQTVYQQEAGLTYNNGPWSVLGRYQHWQTLPPSAAPYGREPQLNVKYTKYNVGGFDFGAE
HHHHHHHHCCCEECCCCHHEEECCHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
ADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHMASYDLTTTTGGVPGQP
CCCCEEEEEECCCCCCCEEEECCEEECCCCCCCEEEECCCEEEEEEEEEEECCCCCCCCC
KRFTYSIPTLSLDTGLVFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDF
CEEEEECCEEECCCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCC
GLAEIFTPNTFVGNDRIADANRLTAALTTRFINPTTGDERARFVIAQQYYFTDQRVTLLP
CCEEEECCCEECCCCCCCCHHHHEEEHHHHCCCCCCCCCCEEEEEEEEEEECCCEEEEEE
TEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVKSSVGFGYSPGERRVINVGY
CCCCCCCCCCCEEEECCEEECCCCCCCCEEEEECCCCEEEHHCCCCCCCCCCCEEEEECE
RYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
EEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEE
GVGVQRYANGLNSSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPL
CCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCH
SRFSNYD
HHCCCCC
>Mature Secondary Structure 
PPKTLFPLVPACDAAPRKKRLAVALLAVPGLVPAVSQAQLSGAAAEPQAFGSPWDLRLA
CCCCCCCCCCCCCCCCCHHHEEEEEEHHCCCCCCHHHHHHCCCCCCCHHCCCCCCEEEC
PQLDEHPQKQGGKPATFVLADHTNGTAEQDLAAKGAAEIRRGNAAVKADAIHYDQDTDMA
CCCCCCHHHCCCCCEEEEEEECCCCCCHHHHHHCCHHHHHCCCCEEEEEEEECCCCCCHH
DAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYRFTATGGTGSAERVQLLDSERSVF
HCCCEEEEECCCCCCCCCCEEEEEECCCCEEECCCEEEEECCCCCCHHHEEEECCCCCEE
TNGTYTGCQCSTNPAWYIKGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGDR
ECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCC
RSGFLPPTFSPFSSTNGFELSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYS
CCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEECCHHHCCCCCCHHHHHHHHHCCCC
GTLTGEYLPDDRVAHRNRYAIFWQHQQNFGNGFGGYVYYNKVSDNLYPEELGSTNQFVNG
CEEECCCCCCCHHCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHCCCHHHHHHH
VQTVYQQEAGLTYNNGPWSVLGRYQHWQTLPPSAAPYGREPQLNVKYTKYNVGGFDFGAE
HHHHHHHHCCCEECCCCHHEEECCHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
ADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHMASYDLTTTTGGVPGQP
CCCCEEEEEECCCCCCCEEEECCEEECCCCCCCEEEECCCEEEEEEEEEEECCCCCCCCC
KRFTYSIPTLSLDTGLVFDRSVRLFGQDFIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDF
CEEEEECCEEECCCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCC
GLAEIFTPNTFVGNDRIADANRLTAALTTRFINPTTGDERARFVIAQQYYFTDQRVTLLP
CCEEEECCCEECCCCCCCCHHHHEEEHHHHCCCCCCCCCCEEEEEEEEEEECCCEEEEEE
TEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVKSSVGFGYSPGERRVINVGY
CCCCCCCCCCCEEEECCEEECCCCCCCCEEEEECCCCEEEHHCCCCCCCCCCCEEEEECE
RYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
EEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEE
GVGVQRYANGLNSSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPL
CCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCH
SRFSNYD
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA