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The map label for this gene is cobU [H]

Identifier: 126452828

GI number: 126452828

Start: 1020090

End: 1020716

Strand: Reverse

Name: cobU [H]

Synonym: BURPS1106A_1044

Alternate gene names: 126452828

Gene position: 1020716-1020090 (Counterclockwise)

Preceding gene: 126452947

Following gene: 126454403

Centisome position: 25.59

GC content: 72.89

Gene sequence:

>627_bases
ATGGCGCGACGCGCGGCGCGCGGCAAATGGCGAAGGCCGCATTATCGCGCGGCCCGTTACAATCACGCGATGATTCCGCG
CGACCTCACCTTCGTTCTCGGCGGCGCGCGCTCGGGCAAGAGCGCGCACGCCGAACGGCTCGCCGCCGCAGGCGGACGGC
CCGTCACCTATATCGCCACCGCCCGCGTCGCGGACGACGAATTCGCCGAGCGCATCGCGCATCATCGCGCGCGCCGGCCG
GCCGGCTGGGCGCTCGTCGAGGCGCCCGTCGAGCTCGCGCCCGCGCTCGCCCGGCTCGACGACGCGAACGCGTGCGTGCT
CGTCGATTGCCTCACGCTGTGGCTCACGAACCTGCTCTGCCCGGCCGACGGCCCGGGCGTCGACGACGCGCGCTGCGACG
CTTACGTCGCCGAACTCGAAGCGGCGCTGCGCGCGAGCCGCGCGCGGGTGATCGTCGTCAGCAACGAGATCGGCTTCGGC
GTCGTGCCGCTCGGCAGGCAGACGCGCCGCTTCGTCGATACGCTCGGCCGCGTCAATCAGCGCATCGCGGCGCTCGCGAC
ACGCGTGACGCTGTGCGTGGCCGGCCTGCCCGTCATGGTCAAGGACGAGGGCGAACCGCGATGCTGA

Upstream 100 bases:

>100_bases
TGCCGCGCGGACGGGCGGCGTTGGCGTTGGCGTTGGCGTTGGCGTTGGCGTTGGCGTTGGCGTTGGCGTTGGCGTTGGCG
TTGGCAATCATCGTGAACGA

Downstream 100 bases:

>100_bases
TGCTGTCGCTGCCCGCCGTCGCCTGCCTCGCGGTCGCCGGCTGCGTCGTCGACAAGCTCGTCGGCGAGCCGCGCGCCGCG
CATCCGCTCGTCGCGTTCGG

Product: cobinamide kinase/cobinamide phosphate guanyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MARRAARGKWRRPHYRAARYNHAMIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRP
AGWALVEAPVELAPALARLDDANACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFG
VVPLGRQTRRFVDTLGRVNQRIAALATRVTLCVAGLPVMVKDEGEPRC

Sequences:

>Translated_208_residues
MARRAARGKWRRPHYRAARYNHAMIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRP
AGWALVEAPVELAPALARLDDANACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFG
VVPLGRQTRRFVDTLGRVNQRIAALATRVTLCVAGLPVMVKDEGEPRC
>Mature_207_residues
ARRAARGKWRRPHYRAARYNHAMIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIATARVADDEFAERIAHHRARRPA
GWALVEAPVELAPALARLDDANACVLVDCLTLWLTNLLCPADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFGV
VPLGRQTRRFVDTLGRVNQRIAALATRVTLCVAGLPVMVKDEGEPRC

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=41.9889502762431, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 22581; Mature: 22450

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRAARGKWRRPHYRAARYNHAMIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIAT
CCCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEE
ARVADDEFAERIAHHRARRPAGWALVEAPVELAPALARLDDANACVLVDCLTLWLTNLLC
ECCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
PADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFGVVPLGRQTRRFVDTLGRVNQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHHH
RIAALATRVTLCVAGLPVMVKDEGEPRC
HHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure 
ARRAARGKWRRPHYRAARYNHAMIPRDLTFVLGGARSGKSAHAERLAAAGGRPVTYIAT
CCCCCCCCCCCCCHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEE
ARVADDEFAERIAHHRARRPAGWALVEAPVELAPALARLDDANACVLVDCLTLWLTNLLC
ECCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
PADGPGVDDARCDAYVAELEAALRASRARVIVVSNEIGFGVVPLGRQTRRFVDTLGRVNQ
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHHHH
RIAALATRVTLCVAGLPVMVKDEGEPRC
HHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]