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The map label for this gene is yfcG [H]

Identifier: 126452802

GI number: 126452802

Start: 1945703

End: 1946407

Strand: Reverse

Name: yfcG [H]

Synonym: BURPS1106A_1980

Alternate gene names: 126452802

Gene position: 1946407-1945703 (Counterclockwise)

Preceding gene: 126454207

Following gene: 126454615

Centisome position: 48.8

GC content: 65.53

Gene sequence:

>705_bases
ATGTCCGATCTTTCCGAATTTCCGATCACGAAGAAATGGCCCGCGCAGCATCCGGAGCGCATCCAGCTCTATTCGCTACC
GACGCCGAACGGCGTCAAGGTATCGATCCTGCTCGAGGAAACGGAGCTGCCGTACGAGGCGCACGTCGTGCGCTTCGACA
CGAACGATCAGATGTCGCCCGAGTTCCTGTCGCTGAACCCGAACAACAAGATTCCGGCGATCATCGATCCGCACGGCCCG
GGCGGCAAGCCGCTCGCGCTGTTCGAATCGGGCGCGATCCTGCTGTATCTCGCCGAGAAGACGGGCCGGTTCATCCCGGC
CGATCCCGCGCGCCGCTACGAGACGATCCAGTGGCTGATGTTCCAGATGGGCGGCATCGGGCCGATGTTCGGCCAGCTCG
GCTTCTTCCACAAGTTCGCGGGCCGCGAGTACGAGGACAAACGCCCGCGCGAGCGCTACGTCGGCGAGGCGAAGCGCCTG
CTCGGCGTGCTTGACGGCCGCCTCGCGCATCGCCGGTGGATCATGGACGACGCCTATACGATCGCCGACATCGCGACGTT
CCCGTGGGTGCGCAACCTGATCGGCTTCTACGAGGCGCGCGAGCTCGTCGAATTCGATCGCTATCCGAACGTGGCGCGCG
CGCTCGACGCGTTCGTCGCGCGGCCGGCGGTGGCGCGCGGATTGAACATTCCGGCGCGGCCGTAG

Upstream 100 bases:

>100_bases
ACGCGCGGGATCGGCTACATTGTGCGGACCGCGCCGCCCGGCGAAGCCCGCCCGTGGGCGCGTCGCGTTTTCTTCACCGA
TTCATCGACCGAGCCCATCC

Downstream 100 bases:

>100_bases
GCGCGGCGTTTCGGTTTCTGTCGTTTCTTTCCGTCGCGCTCCGACGTCCACCGTGCGGCGTTTCGCCGCGCCGCGTCGCG
CGTGCGGCGCGACGCTTGCC

Product: putative glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSDLSEFPITKKWPAQHPERIQLYSLPTPNGVKVSILLEETELPYEAHVVRFDTNDQMSPEFLSLNPNNKIPAIIDPHGP
GGKPLALFESGAILLYLAEKTGRFIPADPARRYETIQWLMFQMGGIGPMFGQLGFFHKFAGREYEDKRPRERYVGEAKRL
LGVLDGRLAHRRWIMDDAYTIADIATFPWVRNLIGFYEARELVEFDRYPNVARALDAFVARPAVARGLNIPARP

Sequences:

>Translated_234_residues
MSDLSEFPITKKWPAQHPERIQLYSLPTPNGVKVSILLEETELPYEAHVVRFDTNDQMSPEFLSLNPNNKIPAIIDPHGP
GGKPLALFESGAILLYLAEKTGRFIPADPARRYETIQWLMFQMGGIGPMFGQLGFFHKFAGREYEDKRPRERYVGEAKRL
LGVLDGRLAHRRWIMDDAYTIADIATFPWVRNLIGFYEARELVEFDRYPNVARALDAFVARPAVARGLNIPARP
>Mature_233_residues
SDLSEFPITKKWPAQHPERIQLYSLPTPNGVKVSILLEETELPYEAHVVRFDTNDQMSPEFLSLNPNNKIPAIIDPHGPG
GKPLALFESGAILLYLAEKTGRFIPADPARRYETIQWLMFQMGGIGPMFGQLGFFHKFAGREYEDKRPRERYVGEAKRLL
GVLDGRLAHRRWIMDDAYTIADIATFPWVRNLIGFYEARELVEFDRYPNVARALDAFVARPAVARGLNIPARP

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=210, Percent_Identity=45.7142857142857, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI87082195, Length=222, Percent_Identity=44.5945945945946, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI87081789, Length=206, Percent_Identity=29.126213592233, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324100, Length=267, Percent_Identity=32.2097378277154, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17864592, Length=200, Percent_Identity=27, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17864598, Length=167, Percent_Identity=32.3353293413174, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17864594, Length=205, Percent_Identity=29.7560975609756, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571670, Length=179, Percent_Identity=26.8156424581006, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26682; Mature: 26551

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLSEFPITKKWPAQHPERIQLYSLPTPNGVKVSILLEETELPYEAHVVRFDTNDQMSP
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCC
EFLSLNPNNKIPAIIDPHGPGGKPLALFESGAILLYLAEKTGRFIPADPARRYETIQWLM
CEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
FQMGGIGPMFGQLGFFHKFAGREYEDKRPRERYVGEAKRLLGVLDGRLAHRRWIMDDAYT
HHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IADIATFPWVRNLIGFYEARELVEFDRYPNVARALDAFVARPAVARGLNIPARP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCCCCCC
>Mature Secondary Structure 
SDLSEFPITKKWPAQHPERIQLYSLPTPNGVKVSILLEETELPYEAHVVRFDTNDQMSP
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCC
EFLSLNPNNKIPAIIDPHGPGGKPLALFESGAILLYLAEKTGRFIPADPARRYETIQWLM
CEEEECCCCCCCEEECCCCCCCCEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
FQMGGIGPMFGQLGFFHKFAGREYEDKRPRERYVGEAKRLLGVLDGRLAHRRWIMDDAYT
HHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IADIATFPWVRNLIGFYEARELVEFDRYPNVARALDAFVARPAVARGLNIPARP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]