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The map label for this gene is fabD [H]

Identifier: 126452756

GI number: 126452756

Start: 2805935

End: 2806867

Strand: Reverse

Name: fabD [H]

Synonym: BURPS1106A_2852

Alternate gene names: 126452756

Gene position: 2806867-2805935 (Counterclockwise)

Preceding gene: 126453602

Following gene: 126452101

Centisome position: 70.37

GC content: 69.35

Gene sequence:

>933_bases
ATGAAATTCGCATTCGTTTTTCCGGGCCAGGGCTCGCAATCGGTCGGCATGCTCAATGCATTCGCCGACGTCGCCGTCGT
GCGCGAGACGCTCGACGAAGCGTCCGATGCGCTTGGCCAGGATATCGGCAAGCTGATCGCCGACGGCCCGGCCGACGAAC
TCAATCTGACGACGAATACGCAACCCGTGATGCTGACGGCCGCGTACGCGTGCTATCGCGCGTGGCAGCAGGCGGGCGGC
GCGCAGCCGTCGATCGTCGCGGGCCACAGCCTCGGCGAATACACGGCGCTCGTCGCCGCGGGCGCGATCGCGTTTCGCGA
CGCGCTGCCGCTCGTGCGCTTTCGCGCGCAGGCGATGCAGACGGCCGTGCCCGTCGGCGTGGGCGGCATGGCGGCGATTC
TCGGGCTCGACGACGACACGGTGCGCGCGGTGTGCGCCGAGGCGTCGGCGACGGGCGTCGTCGAAGCGGTGAACTTCAAC
GCGCCCGCGCAGGTCGTGATCGCGGGCACGAAGGCGGGCATCGAGAAGGCGTGCGAGATCGCGAAGGCGAAGGGCGCGAA
GCGCGCGCTGCCGCTGCCGGTGTCGGCGCCGTTCCATTCGTCGCTGCTCAAGCCCGCGTCGGACAAGCTGCGCGAATATC
TCGCGGGCGTCGACGTGAAGGCGCCGAAGATTTCCGTCGTCAACAACATCGACGTCGCGGTGGTGTCCGATCCCGCGGCG
ATCAAGGATGCGCTCGTGCGCCAGGCGGCGGGCCCCGTGCGCTGGGTCGAGTGCGTGCAGCACATCGCCCGCGAGGGCGT
GACGCACGTGTTCGAGTGCGGTCCGGGCAAGGTGCTCGCCGGCCTCACGAAACGCATCGACGGCAATCTGGTCGGCGCGT
CGGTGTTCGATCCGGCGTCGCTCGACGAAGCGCTCAAGCTCGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
ACGTGGGGCGCGTCGGTCTTCCGCTTCTGACGGCCCTTCTTCGCATCCCATCGGTGCGCCATTCAAGCGCGCCGCTCGAA
TCGATTCAATTGGGGACGAT

Downstream 100 bases:

>100_bases
CGCCGTCAGCGCGCGAGCTTGCCGATTCAACCGAAACACGGAATCACTGCATGGACAAGACTCTCGACAAACAAGTCGCG
ATCGTCACCGGCGCGTCGCG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNTQPVMLTAAYACYRAWQQAGG
AQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQTAVPVGVGGMAAILGLDDDTVRAVCAEASATGVVEAVNFN
APAQVVIAGTKAGIEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDKLREYLAGVDVKAPKISVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVQHIAREGVTHVFECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLAAA

Sequences:

>Translated_310_residues
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNTQPVMLTAAYACYRAWQQAGG
AQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQTAVPVGVGGMAAILGLDDDTVRAVCAEASATGVVEAVNFN
APAQVVIAGTKAGIEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDKLREYLAGVDVKAPKISVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVQHIAREGVTHVFECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLAAA
>Mature_310_residues
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNTQPVMLTAAYACYRAWQQAGG
AQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQTAVPVGVGGMAAILGLDDDTVRAVCAEASATGVVEAVNFN
APAQVVIAGTKAGIEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDKLREYLAGVDVKAPKISVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVQHIAREGVTHVFECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLAAA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=32.890365448505, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=39.2523364485981, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=55.0488599348534, Blast_Score=315, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=31.0580204778157, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=234, Percent_Identity=31.1965811965812, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24665753, Length=308, Percent_Identity=31.1688311688312, Blast_Score=130, Evalue=9e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31864; Mature: 31864

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
QPVMLTAAYACYRAWQQAGGAQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGVGGMAAILGLDDDTVRAVCAEASATGVVEAVNFNAPAQVVIAGTKAGIEKACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDKLREYLAGVDVKAPKISVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCHH
IKDALVRQAAGPVRWVECVQHIAREGVTHVFECGPGKVLAGLTKRIDGNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCEECCCCCCCCH
LDEALKLAAA
HHHHHHHHCC
>Mature Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADVAVVRETLDEASDALGQDIGKLIADGPADELNLTTNT
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
QPVMLTAAYACYRAWQQAGGAQPSIVAGHSLGEYTALVAAGAIAFRDALPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGVGGMAAILGLDDDTVRAVCAEASATGVVEAVNFNAPAQVVIAGTKAGIEKACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDKLREYLAGVDVKAPKISVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCHH
IKDALVRQAAGPVRWVECVQHIAREGVTHVFECGPGKVLAGLTKRIDGNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCEECCCCCCCCH
LDEALKLAAA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]