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The map label for this gene is tpiA [H]

Identifier: 126452700

GI number: 126452700

Start: 1269386

End: 1270186

Strand: Direct

Name: tpiA [H]

Synonym: BURPS1106A_1296

Alternate gene names: 126452700

Gene position: 1269386-1270186 (Clockwise)

Preceding gene: 126453705

Following gene: 126451944

Centisome position: 31.83

GC content: 71.54

Gene sequence:

>801_bases
ATGAACACGACGCCCGGCTTCGGCGCGTCCACGACGAGACAAACGATGTCGAAACAAAGAATCAAGCGGGTGATCGGCAA
CTGGAAGATGCACGGCCGCCTGAGCGGCAACGAGGCGCTGCTCGACGAAGTCGCGCAGGGCGCGCAAGCCGTGCCCGAGC
ACGTCGGCATCGGCGTGTGCGTGCCGTTTCCGTATCTCGCGCAGGCGCGGGCCCGGCTTCACGGCGGTCGCGTCGCGTGG
GGCGCGCAGGACGTGTCCGCGCACGAGCAGGGCGCCTTTACCGGCGAAGTCGCGGCCGGCATGGTCGCGGAGTTCGGCGC
GGCGTACGCGATCGTCGGGCACTCGGAGCGCCGCGCGTATCACGGCGAATCGAACGAGATCGTCGCGGCGAAGGCGCAAC
GTGCGCTCGCCGCGGGGCTGACGCCCGTCGTGTGCGTCGGCGAGACGCTCGCCGAGCGCGAAGCGGGGGCGACCGAGCAG
GTCGTCGGCGTGCAGCTCGACGCGGTGCTCGCGGTGCTGTCGCAGGACGAGGCGGCGCGCATCGTCGTCGCGTACGAGCC
CGTATGGGCGATCGGCACGGGCCGCAGCGCGACGGCGGAGCAGGCGCAGCAGGTGCACGCGTTCCTGCGCGGGCGGCTCG
CGGCGAAGGGCGCCGAGCGCGTGTCGCTGCTGTATGGCGGCAGCGTGAAGGCCGACAACGCGGCCGAGCTGTTCGGCCAG
CCTGACATCGACGGCGGCCTGATCGGCGGCGCGTCGTTGAAGAGCGGGGATTTCCTGGCGATTTGCCGGGCGGCGCAGTA
A

Upstream 100 bases:

>100_bases
ACGTCGGCAAGATCGTGCTCGATTGGGGTGCGAACGCTTGACATCGGTCGTTTGACCGGTTCTTCAGCGTCGCAGTAAAA
TCGCGGGTTCGCTTCGCCAG

Downstream 100 bases:

>100_bases
GCGTTCGCGAGACGCGCGCGACGAATATCGGGGGCGGCCGGCAGGTGCGCCGGTTGCTTGAAACCAAACAGGTGAATGTA
TGCCGTATCTGAAAGTCTTG

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MNTTPGFGASTTRQTMSKQRIKRVIGNWKMHGRLSGNEALLDEVAQGAQAVPEHVGIGVCVPFPYLAQARARLHGGRVAW
GAQDVSAHEQGAFTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNEIVAAKAQRALAAGLTPVVCVGETLAEREAGATEQ
VVGVQLDAVLAVLSQDEAARIVVAYEPVWAIGTGRSATAEQAQQVHAFLRGRLAAKGAERVSLLYGGSVKADNAAELFGQ
PDIDGGLIGGASLKSGDFLAICRAAQ

Sequences:

>Translated_266_residues
MNTTPGFGASTTRQTMSKQRIKRVIGNWKMHGRLSGNEALLDEVAQGAQAVPEHVGIGVCVPFPYLAQARARLHGGRVAW
GAQDVSAHEQGAFTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNEIVAAKAQRALAAGLTPVVCVGETLAEREAGATEQ
VVGVQLDAVLAVLSQDEAARIVVAYEPVWAIGTGRSATAEQAQQVHAFLRGRLAAKGAERVSLLYGGSVKADNAAELFGQ
PDIDGGLIGGASLKSGDFLAICRAAQ
>Mature_266_residues
MNTTPGFGASTTRQTMSKQRIKRVIGNWKMHGRLSGNEALLDEVAQGAQAVPEHVGIGVCVPFPYLAQARARLHGGRVAW
GAQDVSAHEQGAFTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNEIVAAKAQRALAAGLTPVVCVGETLAEREAGATEQ
VVGVQLDAVLAVLSQDEAARIVVAYEPVWAIGTGRSATAEQAQQVHAFLRGRLAAKGAERVSLLYGGSVKADNAAELFGQ
PDIDGGLIGGASLKSGDFLAICRAAQ

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=255, Percent_Identity=42.7450980392157, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI226529917, Length=255, Percent_Identity=42.7450980392157, Blast_Score=185, Evalue=4e-47,
Organism=Escherichia coli, GI1790353, Length=251, Percent_Identity=48.605577689243, Blast_Score=216, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17536593, Length=243, Percent_Identity=46.0905349794239, Blast_Score=194, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320255, Length=243, Percent_Identity=39.917695473251, Blast_Score=176, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28572004, Length=268, Percent_Identity=42.910447761194, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI28572008, Length=247, Percent_Identity=45.3441295546559, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI28572006, Length=247, Percent_Identity=45.3441295546559, Blast_Score=187, Evalue=9e-48,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 27626; Mature: 27626

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTPGFGASTTRQTMSKQRIKRVIGNWKMHGRLSGNEALLDEVAQGAQAVPEHVGIGVC
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
VPFPYLAQARARLHGGRVAWGAQDVSAHEQGAFTGEVAAGMVAEFGAAYAIVGHSERRAY
ECCHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCHHHHHHHHHHHCCEEEEEECCHHHCC
HGESNEIVAAKAQRALAAGLTPVVCVGETLAEREAGATEQVVGVQLDAVLAVLSQDEAAR
CCCCCCEEHHHHHHHHHHCCCHHEECCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEE
IVVAYEPVWAIGTGRSATAEQAQQVHAFLRGRLAAKGAERVSLLYGGSVKADNAAELFGQ
EEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCC
PDIDGGLIGGASLKSGDFLAICRAAQ
CCCCCCEECCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MNTTPGFGASTTRQTMSKQRIKRVIGNWKMHGRLSGNEALLDEVAQGAQAVPEHVGIGVC
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEE
VPFPYLAQARARLHGGRVAWGAQDVSAHEQGAFTGEVAAGMVAEFGAAYAIVGHSERRAY
ECCHHHHHHHHHHCCCEEEECCCCCCHHHCCCCCHHHHHHHHHHHCCEEEEEECCHHHCC
HGESNEIVAAKAQRALAAGLTPVVCVGETLAEREAGATEQVVGVQLDAVLAVLSQDEAAR
CCCCCCEEHHHHHHHHHHCCCHHEECCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEE
IVVAYEPVWAIGTGRSATAEQAQQVHAFLRGRLAAKGAERVSLLYGGSVKADNAAELFGQ
EEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCC
PDIDGGLIGGASLKSGDFLAICRAAQ
CCCCCCEECCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA