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The map label for this gene is pdxY [H]

Identifier: 126452669

GI number: 126452669

Start: 2761051

End: 2761980

Strand: Direct

Name: pdxY [H]

Synonym: BURPS1106A_2802

Alternate gene names: 126452669

Gene position: 2761051-2761980 (Clockwise)

Preceding gene: 126453281

Following gene: 126453784

Centisome position: 69.23

GC content: 68.39

Gene sequence:

>930_bases
ATGCGGGAAAGTCATGTATCGTTCGACGTAATCCGGCGAGCTCGCCGCGCGCCGGCACACTCGATCATGAAAAACGTCCT
CAGCATCCAGTCGCACGTCATCTACGGACATGCGGGCAACAGCGCCGCAGTGTTTCCGATGCAACGGCTCGGCGTCAATG
TCTGGCCGCTCAACACCGTGCAGTTGTCGAACCACATGCAGTACGGCCATTGGGCGGGCAGCGCGATCGACGCGGCGAAG
ATGGAGCAGCTCGTCGACGGCATCGCGGCGATCGGCGCGCTCAAGCGCTGCGACGCGGTGCTCTCGGGCTTCCTCGGCTC
GCCCGCGCAGGCGCGCGCGGCGGTCGAGATCGTGCGCACCGTGAAGGCGACGAATCTGAACGCGTGGTACTTCTGCGATC
CGGCGATGGGCCAGACGGGCGGCATCCGGCCGGAGCCCGGCGTCGAGGAGTTCATCGTCGCCGAGCTGCCCGAGCTCGCG
GACGGCATGGCGCCCAATCACAGCGAGCTGCAAAAGCTCGCCGGGCAACGCATCGAGACGGTCGCCGAGGCCGTCGCCGC
GTGCCGCTCGATCATCCGCCGCGGCCCGCAGGTGATCCTCGTCAAGCATTTGCACGATCGCAACAGCCCCGCCGACCGTT
TCAACATGCTCGTCGTCACCGAGACCGAAGCATGGATCGGCCAGCGGCCGCTGTACGCGTTCCCGCGGCATCCGGTCGGC
GTCGGCGACCTGACGAGCGCGATCTTCGTCGCACGGCGACTGCGCGGCGACAGCGTGCGCGCCGCGTTCGAGCACACGCT
CGCCGCCGTGCACGCGGTCGTCAAGGCGACCTACGACGCACGGCGCTACGAGCTCGAGCTCGTCGCCGCGCAGGACGAGA
TCGCGCGGCCGAGCGAGTGGTTCGGCGCGTGGGTCACGGGCGCGGATTGA

Upstream 100 bases:

>100_bases
TGAAGGAGGCGGCTCGCCCGACATCCGTGCAAGCCTCGCGCCATTTTACTTTCGGCGGGCTGACGCCCCTCCGATACCGT
ATTACCGGATGCTTCCGTGA

Downstream 100 bases:

>100_bases
TGCGCGGCGCGCGCCGGTTCGCGTGTTGATCCGCACGCTCGATCGCGCGCCCCCGTTCGAGCCGCCGCGGCGGCGCCACG
CGGTGTCGCGGCACCCGTCG

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRESHVSFDVIRRARRAPAHSIMKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAK
MEQLVDGIAAIGALKRCDAVLSGFLGSPAQARAAVEIVRTVKATNLNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELA
DGMAPNHSELQKLAGQRIETVAEAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVG
VGDLTSAIFVARRLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD

Sequences:

>Translated_309_residues
MRESHVSFDVIRRARRAPAHSIMKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAK
MEQLVDGIAAIGALKRCDAVLSGFLGSPAQARAAVEIVRTVKATNLNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELA
DGMAPNHSELQKLAGQRIETVAEAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVG
VGDLTSAIFVARRLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD
>Mature_309_residues
MRESHVSFDVIRRARRAPAHSIMKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTVQLSNHMQYGHWAGSAIDAAK
MEQLVDGIAAIGALKRCDAVLSGFLGSPAQARAAVEIVRTVKATNLNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELA
DGMAPNHSELQKLAGQRIETVAEAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVG
VGDLTSAIFVARRLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEWFGAWVTGAD

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=271, Percent_Identity=30.9963099630996, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1787924, Length=284, Percent_Identity=52.112676056338, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1788758, Length=270, Percent_Identity=25.1851851851852, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17507759, Length=263, Percent_Identity=30.0380228136882, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17507757, Length=273, Percent_Identity=28.9377289377289, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6324354, Length=275, Percent_Identity=32, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6320806, Length=275, Percent_Identity=29.4545454545455, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=28.7671232876712, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 33766; Mature: 33766

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRESHVSFDVIRRARRAPAHSIMKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCEECCHHHHCCEECCCCEE
QLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLSGFLGSPAQARAAVEIVRT
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VKATNLNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELADGMAPNHSELQKLAGQRIET
HHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAEAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEEEEEEECHHHHCCCCCCCCCCCCCC
VGDLTSAIFVARRLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHCCCHHH
FGAWVTGAD
HCCEECCCC
>Mature Secondary Structure
MRESHVSFDVIRRARRAPAHSIMKNVLSIQSHVIYGHAGNSAAVFPMQRLGVNVWPLNTV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEEECCCCCEECCHHHHCCEECCCCEE
QLSNHMQYGHWAGSAIDAAKMEQLVDGIAAIGALKRCDAVLSGFLGSPAQARAAVEIVRT
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VKATNLNAWYFCDPAMGQTGGIRPEPGVEEFIVAELPELADGMAPNHSELQKLAGQRIET
HHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
VAEAVAACRSIIRRGPQVILVKHLHDRNSPADRFNMLVVTETEAWIGQRPLYAFPRHPVG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHEEEEEEEECHHHHCCCCCCCCCCCCCC
VGDLTSAIFVARRLRGDSVRAAFEHTLAAVHAVVKATYDARRYELELVAAQDEIARPSEW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHCCCHHH
FGAWVTGAD
HCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA