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The map label for this gene is mdtA [H]

Identifier: 126452619

GI number: 126452619

Start: 1343127

End: 1344464

Strand: Reverse

Name: mdtA [H]

Synonym: BURPS1106A_1369

Alternate gene names: 126452619

Gene position: 1344464-1343127 (Counterclockwise)

Preceding gene: 126453037

Following gene: 126455284

Centisome position: 33.71

GC content: 69.96

Gene sequence:

>1338_bases
ATGGACAATCAAGAAAAGCCCACGCACCGCTCTCCCGCTCCCGCGCCCTCCGGTCCCCGCCCGCGCCGCCCGCGCCGCAG
GCTGATCGCATTCGGCGTGCTCGCGGCCGTCGCGATCGGCGCCCTGCTGTGGTGGCATCCGTGGAAGAGCGGCGGCACCC
CGAGCGCCCAGGGCCAGCCGGGCGGCGCGCGCAAGCGGGGCGGCCCCGCCGCGCTCGCGAACCTGCCGCAGCCGGTGCAG
GTCGCCACGGCGGCGCGCGGCGAGATGCCCGTCGTCCTCAACGCGCTCGGCACCGTCACGCCGCTCGCGAACGTGACCGT
CCGGACCCAGTTGTCCGGCTATCTGCAGGCGGTGTCGTTCCAGGAAGGCCAGATCGTGAAGAAGGGCGACGTGCTCGCGC
AAATCGATCCGCGCCCGTACCAGATCTCGCTCGCGAACGCGCAAGGCGCGCTCGCGCGCGACGAGGCGCTCCTCGCGACC
GCGCGCCTCGACCTGAAGCGCTATCAGACGCTCGTCGCGCAAGACTCGATCGCGAAGCAGACGGCCGACACGCAGGCCTC
GCTCGTCAAGCAGTACGAAGGCACCGTGCAGATCGACCGCGCGGCGATCGACTCCGCGAAGCTCAATCTCGCGTACGCGC
GCATCACCGCGCCCGTGTCGGGCCGCGTCGGCCTGCGGCAGGTGGACCCGGGCAATTACGTGACGCCGTCGGACACGAAC
GGCATCGTCGTCATCACGCAACTGCAGCCGATGAGCGTGATCTTCACCACGTCGGAGGACAATCTGCCCGCGATCCTCAA
GCAGGTGGGCGCGGGCGGCAAGCTGTCGGTCACCGCGTACAACCGCAACAACACGACGCCGCTCGAGACGGGCGTGCTCG
ACACGCTCGACAACCAGATCGACACGGCCACCGGCACCGTGAAGCTGCGCGCTCGCTTCGAGAACCGGAACAACCTGCTG
TTCCCGAATCAGTTCGTCAACACGCGGCTGCTCGTCGACACGATCCGCGATGCGACGATCGTGCCGACGTCGGCCGTGCT
CACGGGCTCGATCGGCCAGTTCGTCTACGTCGTGAAGCCGGACAACACGGTGAGCGTGCGCAAGGTGAAGCCCGGCCCCA
TCGACGGCGAGCGCACGAGCATCGTCGAGGGGCTCGCCGTCGGCGAGCGCGTCGTGACGGACGGCTCCGACCGGTTGCGC
GAAGGCTCGGCGGTGACGATCCCGGCCGACAAGCCGAAGCAGGCTTCGGGCGCAAGAAGCGCTTCAGGCGCTTCGGACGC
TTCGGACGCGCACGGCGGGCACCGTCGCCGCGGCGCGTCGCAAGCCCGATCGCAATGA

Upstream 100 bases:

>100_bases
CGTCGCGACCGGGCCGCGGCCGGCCCGCGTCGCGCCGACCGCGAACGCGGCCCGTGCGCGCCCGTCGTATGCGCCGCACG
CCGACCTCCAGATCGAACCG

Downstream 100 bases:

>100_bases
CGCCGGCTGACCGATGAATCCGTCCCGCGTCTTCATTCTCCGGCCGGTCGGCACCGCGCTCCTGATGGCGGCGATCATGC
TCGCCGGCCTCGTCGCGCTG

Product: membrane fusion protein MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDNQEKPTHRSPAPAPSGPRPRRPRRRLIAFGVLAAVAIGALLWWHPWKSGGTPSAQGQPGGARKRGGPAALANLPQPVQ
VATAARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLAT
ARLDLKRYQTLVAQDSIAKQTADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTN
GIVVITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTATGTVKLRARFENRNNLL
FPNQFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNTVSVRKVKPGPIDGERTSIVEGLAVGERVVTDGSDRLR
EGSAVTIPADKPKQASGARSASGASDASDAHGGHRRRGASQARSQ

Sequences:

>Translated_445_residues
MDNQEKPTHRSPAPAPSGPRPRRPRRRLIAFGVLAAVAIGALLWWHPWKSGGTPSAQGQPGGARKRGGPAALANLPQPVQ
VATAARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLAT
ARLDLKRYQTLVAQDSIAKQTADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTN
GIVVITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTATGTVKLRARFENRNNLL
FPNQFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNTVSVRKVKPGPIDGERTSIVEGLAVGERVVTDGSDRLR
EGSAVTIPADKPKQASGARSASGASDASDAHGGHRRRGASQARSQ
>Mature_445_residues
MDNQEKPTHRSPAPAPSGPRPRRPRRRLIAFGVLAAVAIGALLWWHPWKSGGTPSAQGQPGGARKRGGPAALANLPQPVQ
VATAARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSFQEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLAT
ARLDLKRYQTLVAQDSIAKQTADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTN
GIVVITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQIDTATGTVKLRARFENRNNLL
FPNQFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKPDNTVSVRKVKPGPIDGERTSIVEGLAVGERVVTDGSDRLR
EGSAVTIPADKPKQASGARSASGASDASDAHGGHRRRGASQARSQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=359, Percent_Identity=48.4679665738162, Blast_Score=337, Evalue=7e-94,
Organism=Escherichia coli, GI1789929, Length=331, Percent_Identity=29.3051359516616, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1789665, Length=315, Percent_Identity=34.6031746031746, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786668, Length=354, Percent_Identity=31.638418079096, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081796, Length=341, Percent_Identity=28.7390029325513, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081951, Length=182, Percent_Identity=30.2197802197802, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47149; Mature: 47149

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQEKPTHRSPAPAPSGPRPRRPRRRLIAFGVLAAVAIGALLWWHPWKSGGTPSAQGQP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GGARKRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSF
CCCCCCCCCHHHHCCCCCCEEHHHCCCCCCEEEHHHHCCCCCCCEEEEEHHHHHHHEEEC
QEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLVAQDSIAKQ
CCCCEEECCCEEEEECCCCEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
TADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTN
HHHHHHHHHHHCCCCEEEEHHHHCCCCEEEEEEEEECCCCCCCCCEEECCCCEECCCCCC
GIVVITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQI
CEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHCHHHHHCCCC
DTATGTVKLRARFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKP
CCCCCEEEEEEEECCCCCEECCCHHCCCEEEEEHHCCCEECCCHHHEECCCCCEEEEECC
DNTVSVRKVKPGPIDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKPKQASGARS
CCEEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEECCCCCCCCCCCCC
ASGASDASDAHGGHRRRGASQARSQ
CCCCCCCCCCCCCHHHCCCHHHCCC
>Mature Secondary Structure
MDNQEKPTHRSPAPAPSGPRPRRPRRRLIAFGVLAAVAIGALLWWHPWKSGGTPSAQGQP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GGARKRGGPAALANLPQPVQVATAARGEMPVVLNALGTVTPLANVTVRTQLSGYLQAVSF
CCCCCCCCCHHHHCCCCCCEEHHHCCCCCCEEEHHHHCCCCCCCEEEEEHHHHHHHEEEC
QEGQIVKKGDVLAQIDPRPYQISLANAQGALARDEALLATARLDLKRYQTLVAQDSIAKQ
CCCCEEECCCEEEEECCCCEEEEEECCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
TADTQASLVKQYEGTVQIDRAAIDSAKLNLAYARITAPVSGRVGLRQVDPGNYVTPSDTN
HHHHHHHHHHHCCCCEEEEHHHHCCCCEEEEEEEEECCCCCCCCCEEECCCCEECCCCCC
GIVVITQLQPMSVIFTTSEDNLPAILKQVGAGGKLSVTAYNRNNTTPLETGVLDTLDNQI
CEEEEEECCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHCHHHHHCCCC
DTATGTVKLRARFENRNNLLFPNQFVNTRLLVDTIRDATIVPTSAVLTGSIGQFVYVVKP
CCCCCEEEEEEEECCCCCEECCCHHCCCEEEEEHHCCCEECCCHHHEECCCCCEEEEECC
DNTVSVRKVKPGPIDGERTSIVEGLAVGERVVTDGSDRLREGSAVTIPADKPKQASGARS
CCEEEEEEECCCCCCCCHHHHHHHHHHCCEEECCCHHHHCCCCEEEECCCCCCCCCCCCC
ASGASDASDAHGGHRRRGASQARSQ
CCCCCCCCCCCCCHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA