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The map label for this gene is etfA [H]

Identifier: 126452539

GI number: 126452539

Start: 2870954

End: 2871889

Strand: Reverse

Name: etfA [H]

Synonym: BURPS1106A_2927

Alternate gene names: 126452539

Gene position: 2871889-2870954 (Counterclockwise)

Preceding gene: 126454707

Following gene: 126453376

Centisome position: 72.01

GC content: 67.52

Gene sequence:

>936_bases
ATGACGATTCTGGTGATTGCGGAACACGACAACGCGTCGATCAAGGCGGCCACGCTGAACACGGTGGCGGCGGCGACGAA
GATCGGCGGCGACATTCACGTGCTGGTGGCGGGCCATAACGCGCAGGGCGCGGCGGACGCCGCGGCGAAGATCGCGGGCG
TGAGCAAGGTGCTGCTGGCCGATGCGCCGCAACTGGCGGACGGTCTCGCGGAAAACGTCGAGGCGACCGCGCTGAACGTC
GCGAAGGACTACTCGCACATCCTCGCGCCGGCGACCGCGTACGGCAAGAACATCGCGCCGCGGATCGCGGCGAAGCTCGA
CGTCGCGCAGATCTCGGACATCACGGCAGTCGATTCGGCCGATACGTTCGAGCGCCCGATTTACGCGGGCAACGCGATCG
CGACGGTGCAGTCGAGCGACCCGATCAAGGTGATCACGGTGCGCGCGACGGGCTTCGACCCGGTCGCGGCGCAAGGCGGC
AGCGCGTCGGTCGAGAAGATCGACGCGGCGGCGGACGCGGGCGTGTCGCAGTTCGTGAGCCGCGAGGTGACGAAGCTCGA
TCGTCCGGAGCTCACGAGCGCGAGCATCATCGTGTCGGGCGGCCGCGGCCTCGGCAGCGGCGAGAACTACACGAAGGTGC
TGGAGCCGCTCGCGGACAAGCTGCAGGCGGCGCTGGGCGCATCGCGCGCGGCGGTGGACGCGGGCTACGTGCCGAACGAT
TATCAAGTGGGCCAGACGGGCAAGATCGTCGCGCCGCAGCTGTATATCGCGGTGGGCATCTCGGGCGCGATCCAGCACTT
GGCGGGGATGAAGGATTCGAAGGTGATCGTCGCGATCAACAAGGATCCGGAAGCGCCGATCTTCAGCGTGGCCGATTACG
GCCTCGTCGGCGATCTGTTCACGCTCGTGCCGGAACTCGTGAACGAGCTCGGCTGA

Upstream 100 bases:

>100_bases
GCCGCCCAAGCGCGCGGCGGGCGTGAAGGTCGCGGACGTGAAGACGCTGGTCGAGAAGCTGAAGACCGAAGCCAAGGTGC
TGTAAGGGGAGCGCAAGGAA

Downstream 100 bases:

>100_bases
CACGTTCAGCCGCCGGCGCGCGTCGCGTTCAGCGCACGAGCCAGTCGAACATGAACAAAGGGGCGCGGCGAGCGCCCCTT
TTCACACCATAAGCAGACTA

Product: electron transfer flavoprotein, alpha subunit

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTILVIAEHDNASIKAATLNTVAAATKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLADAPQLADGLAENVEATALNV
AKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAQGG
SASVEKIDAAADAGVSQFVSREVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLQAALGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLFTLVPELVNELG

Sequences:

>Translated_311_residues
MTILVIAEHDNASIKAATLNTVAAATKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLADAPQLADGLAENVEATALNV
AKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAQGG
SASVEKIDAAADAGVSQFVSREVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLQAALGASRAAVDAGYVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLFTLVPELVNELG
>Mature_310_residues
TILVIAEHDNASIKAATLNTVAAATKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLADAPQLADGLAENVEATALNVA
KDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSADTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAQGGS
ASVEKIDAAADAGVSQFVSREVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLQAALGASRAAVDAGYVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLFTLVPELVNELG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=59.1639871382637, Blast_Score=356, Evalue=1e-98,
Organism=Homo sapiens, GI189181759, Length=275, Percent_Identity=59.6363636363636, Blast_Score=317, Evalue=1e-86,
Organism=Escherichia coli, GI1787990, Length=258, Percent_Identity=33.7209302325581, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786226, Length=230, Percent_Identity=35.6521739130435, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082157, Length=254, Percent_Identity=31.8897637795276, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=55.7692307692308, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6325261, Length=318, Percent_Identity=44.0251572327044, Blast_Score=254, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17136898, Length=312, Percent_Identity=60.8974358974359, Blast_Score=355, Evalue=3e-98,
Organism=Drosophila melanogaster, GI24652801, Length=312, Percent_Identity=60.8974358974359, Blast_Score=355, Evalue=3e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31642; Mature: 31511

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILVIAEHDNASIKAATLNTVAAATKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLA
CEEEEEEECCCCEEEEEEHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DAPQLADGLAENVEATALNVAKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCHHHHCCEEECCCC
DTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAQGGSASVEKIDAAADAGVSQFVS
CHHCCCEECCCEEEEEECCCCEEEEEEEECCCCCHHCCCCCCCHHHHHHHHHCCHHHHHH
REVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLQAALGASRAAVDAGYVPND
HHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHCCCHHHHHH
TLVPELVNELG
HHHHHHHHHCC
>Mature Secondary Structure 
TILVIAEHDNASIKAATLNTVAAATKIGGDIHVLVAGHNAQGAADAAAKIAGVSKVLLA
EEEEEEECCCCEEEEEEHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
DAPQLADGLAENVEATALNVAKDYSHILAPATAYGKNIAPRIAAKLDVAQISDITAVDSA
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHCCHHHHCCEEECCCC
DTFERPIYAGNAIATVQSSDPIKVITVRATGFDPVAAQGGSASVEKIDAAADAGVSQFVS
CHHCCCEECCCEEEEEECCCCEEEEEEEECCCCCHHCCCCCCCHHHHHHHHHCCHHHHHH
REVTKLDRPELTSASIIVSGGRGLGSGENYTKVLEPLADKLQAALGASRAAVDAGYVPND
HHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFSVADYGLVGDLF
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEHHCCCHHHHHH
TLVPELVNELG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]