Click here to switch to the map view.

The map label for this gene is panE [H]

Identifier: 126452512

GI number: 126452512

Start: 878045

End: 879001

Strand: Direct

Name: panE [H]

Synonym: BURPS1106A_0892

Alternate gene names: 126452512

Gene position: 878045-879001 (Clockwise)

Preceding gene: 126452957

Following gene: 126454908

Centisome position: 22.01

GC content: 73.98

Gene sequence:

>957_bases
ATGGCGACGATCGAGATGACGGCGTTGAGGATTGCGATGCTCGGCGCGGGCGCGATGGGCTCGCTGTTCGGCGGATTGCT
CGCCGAGTGCGGGCACGACGTGACGCTCGTCGACGTGAACGCCGCGCATGTCGACGCGATCGCGCGCGACGGATTGCGGC
TCGACACCGATCGCGGCGAGCGGCGCGTCGCGCGGCTCGCCGCGCTGCGCCCGGACGGCGTCGCCGCGCACGCGGGCATG
CCGCCCGACCTGGTGATCGTGTTCACGAAGACGCTGCACACGCGCGCGGCGCTCGCGGGCGCGCGCGCGCTCTTCGGCCC
GCGCACGCACGCGCTGACGCTGCAGAACGGGCTCGGCAATGTCGAGACGCTCGCCGAATACGTGCCGCTCGAGCGGATTC
TCGTCGGCGTGACGACGTGGCCCGCCGATCTCGCCGGGCCCGCGCACGTGCGCTCGCACGGCGCGGGCTGGGTGAGGCTG
ATGAGCGCGGACGGCGCGATGCGGCCGATCGTGCAGGCGAGCGCGCACGCGCTCGATCGCGCCGGCTTGAACTGCGCGAT
CGACACGGGCGTGTGGGCGACGATCCGGGAGAAGGTCGGCTTCAACGCGGCGCTCAACACGCTGTGTGCGCTCACGCGCG
GCACGGTCGACGCGCTCGGCGCGCGCGAGGACGGGCCGGCGCTCGCGCTTGCGATCGTCGCGGAGGTCGCGGCGGTGGCG
CGCGCGAAGGGCGTCGGCGCCGACGAGCGCCGGATGCGCGAGAACGTGCTGCACGCGATCCGCGAGCACCGCGGACATCG
GCCGTCGATGCTGCAGGACGTGCTCGCGGGGCGGCGCACCGAGATCGACGCGATCAACGGCGCGGTGGTCGCGGCCGCGG
GCGAGCTTGGCGTGGCGGTGCCGCATGTGCGGACGCTGTTGCAGCTCGTCAGGCTGATCGACGCGCAGGGCGGGTGA

Upstream 100 bases:

>100_bases
GGCTTCGGCCACTTCGGCGGCAAGGCGGGCATCGCCGAGTTCACCGATCTGCGCTGGATCACCGTGCAGACGGCTCCGCG
CCACTATCCGTTCTGAAACG

Downstream 100 bases:

>100_bases
CGTGGCGCGGGCAACGAAGCGGACAGGGGCCGCGGGAGGCTGCGCGACGGCGGCCGTGCGGCTGCGGGAGCGCCGTGAAC
GCGTTGTGGCGACGCGGTGA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MATIEMTALRIAMLGAGAMGSLFGGLLAECGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAALRPDGVAAHAGM
PPDLVIVFTKTLHTRAALAGARALFGPRTHALTLQNGLGNVETLAEYVPLERILVGVTTWPADLAGPAHVRSHGAGWVRL
MSADGAMRPIVQASAHALDRAGLNCAIDTGVWATIREKVGFNAALNTLCALTRGTVDALGAREDGPALALAIVAEVAAVA
RAKGVGADERRMRENVLHAIREHRGHRPSMLQDVLAGRRTEIDAINGAVVAAAGELGVAVPHVRTLLQLVRLIDAQGG

Sequences:

>Translated_318_residues
MATIEMTALRIAMLGAGAMGSLFGGLLAECGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAALRPDGVAAHAGM
PPDLVIVFTKTLHTRAALAGARALFGPRTHALTLQNGLGNVETLAEYVPLERILVGVTTWPADLAGPAHVRSHGAGWVRL
MSADGAMRPIVQASAHALDRAGLNCAIDTGVWATIREKVGFNAALNTLCALTRGTVDALGAREDGPALALAIVAEVAAVA
RAKGVGADERRMRENVLHAIREHRGHRPSMLQDVLAGRRTEIDAINGAVVAAAGELGVAVPHVRTLLQLVRLIDAQGG
>Mature_317_residues
ATIEMTALRIAMLGAGAMGSLFGGLLAECGHDVTLVDVNAAHVDAIARDGLRLDTDRGERRVARLAALRPDGVAAHAGMP
PDLVIVFTKTLHTRAALAGARALFGPRTHALTLQNGLGNVETLAEYVPLERILVGVTTWPADLAGPAHVRSHGAGWVRLM
SADGAMRPIVQASAHALDRAGLNCAIDTGVWATIREKVGFNAALNTLCALTRGTVDALGAREDGPALALAIVAEVAAVAR
AKGVGADERRMRENVLHAIREHRGHRPSMLQDVLAGRRTEIDAINGAVVAAAGELGVAVPHVRTLLQLVRLIDAQGG

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=306, Percent_Identity=27.1241830065359, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 33200; Mature: 33069

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIEMTALRIAMLGAGAMGSLFGGLLAECGHDVTLVDVNAAHVDAIARDGLRLDTDRGE
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEECCCCHH
RRVARLAALRPDGVAAHAGMPPDLVIVFTKTLHTRAALAGARALFGPRTHALTLQNGLGN
HHHHHHHHCCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
VETLAEYVPLERILVGVTTWPADLAGPAHVRSHGAGWVRLMSADGAMRPIVQASAHALDR
HHHHHHHCCHHHHHHCCCCCCHHHCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
AGLNCAIDTGVWATIREKVGFNAALNTLCALTRGTVDALGAREDGPALALAIVAEVAAVA
CCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHH
RAKGVGADERRMRENVLHAIREHRGHRPSMLQDVLAGRRTEIDAINGAVVAAAGELGVAV
HHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCCCEEEEECCCCCCCH
PHVRTLLQLVRLIDAQGG
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATIEMTALRIAMLGAGAMGSLFGGLLAECGHDVTLVDVNAAHVDAIARDGLRLDTDRGE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCEECCCCHH
RRVARLAALRPDGVAAHAGMPPDLVIVFTKTLHTRAALAGARALFGPRTHALTLQNGLGN
HHHHHHHHCCCCCCEECCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
VETLAEYVPLERILVGVTTWPADLAGPAHVRSHGAGWVRLMSADGAMRPIVQASAHALDR
HHHHHHHCCHHHHHHCCCCCCHHHCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
AGLNCAIDTGVWATIREKVGFNAALNTLCALTRGTVDALGAREDGPALALAIVAEVAAVA
CCCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHH
RAKGVGADERRMRENVLHAIREHRGHRPSMLQDVLAGRRTEIDAINGAVVAAAGELGVAV
HHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCCCEEEEECCCCCCCH
PHVRTLLQLVRLIDAQGG
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]