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The map label for this gene is hisC

Identifier: 126452351

GI number: 126452351

Start: 3634970

End: 3636040

Strand: Reverse

Name: hisC

Synonym: BURPS1106A_3723

Alternate gene names: 126452351

Gene position: 3636040-3634970 (Counterclockwise)

Preceding gene: 126453408

Following gene: 126454968

Centisome position: 91.16

GC content: 69.47

Gene sequence:

>1071_bases
ATGACTACGCCAGAAGACATCATCCGCCGCGACGTGCTCGCGATGACGGGCTACCCGGTGCCGGACGCAACGGGCTTCGT
GAAGCTCGACGCGATGGAGAACCCGTATTCGCTGCCCGCGCCGCTCGCGGCCGAGCTCGGCGAGCGGCTCGCGCACGTCG
CGCTGAACCGCTATCCCGCGCCGCGCCCCGCCGCGCTGATCGACCGGCTGCGCGCCGTGACGGGCGTGCCCGCCGCGTGC
GACGTGCTGCTCGGCAACGGCTCGGACGAGATCATCAGCATGCTCGCGATGGCGTGCGCGAAGCCGGGCGCGAAGGTGCT
CGCGCCGGTGCCGGGCTTCGTGATGTACGAGCTGTCGGCGAAGTTCGCGCAGCTCGAGTTCGTCGGCGTGCCGCTTCGCG
CGGACCTCACGCTCGACATCGACGCGATGCTCGCGGCGCTCGCCGAGCACCGGCCGGCGCTCGTCTATCTCGCGTATCCG
AACAACCCGACGGGCACGCTGTACCCGGACGAGGACGTCGAGCGGATCATCGCGGCCGCCGCCGCGAGCCTCGTCGTGAT
CGACGAGGCGTACCAGCCGTTCGCGCAGCGCAGTTGGCTGCCGCGCGCGGCCCAGTTCGACAACGTCGTCGTGATGCGCA
CGATGTCGAAGCTCGGCCTGGCGGGCATTCGCCTCGGCTATCTGGTCGGGCTGCCGGCATGGCTCGTGCAGTTCGACAAG
GTGCGCCCGCCGTACAACGTGAACGTGCTGACGCAGGCGGCGGCGGAATTCCTGCTCGAGCGCGTCGACGTGCTCGACGC
GCAGGCCGCGCAACTGCGCGACGCGCGCACGGCGCTCGCGCACGCGATCGGCGCGCTGCCGGGCGCCACCGTGTTCCCGA
GCGCGGGCAATTTCCTGCTCGTACGGGTGCCGGACGCGGCCGCCGTGTTCGATGTGCTTTTGACCGAGCGGGTATTGATC
AAAAACGTGAGTAAAATGCATCCATTGCTCGCCAATTGCGTGCGCGTGACGGTTGGGTCTCCCGAAGAAAACGCGCGCCT
GCTGGCCGCACTGAAGCTGGCGCTGCCCTGA

Upstream 100 bases:

>100_bases
ACCCGAGACCGCCCGGCGAGGCGTCTCGCGCGGCGCGACCGGTGCGCCGCGCGGGACGCCTTGGCCGGGGCCACGCCGGC
GCCCGCGCGCCTTTGCCACC

Downstream 100 bases:

>100_bases
CGGGCCACCCCGGGGCGCCGCCTTTCTCGTCCCCATTTGCCTTAGTCATTTCAAGGAAACACCATGCGCGTGGCGCAAGT
CGTTCGCAACACCAGCGAAA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVTGVPAAC
DVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYP
NNPTGTLYPDEDVERIIAAAAASLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLLVRVPDAAAVFDVLLTERVLI
KNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP

Sequences:

>Translated_356_residues
MTTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVTGVPAAC
DVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYP
NNPTGTLYPDEDVERIIAAAAASLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLLVRVPDAAAVFDVLLTERVLI
KNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
>Mature_355_residues
TTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPAPRPAALIDRLRAVTGVPAACD
VLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSAKFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYPN
NPTGTLYPDEDVERIIAAAAASLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDKV
RPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLLVRVPDAAAVFDVLLTERVLIK
NVSKMHPLLANCVRVTVGSPEENARLLAALKLALP

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily

Homologues:

Organism=Escherichia coli, GI1788332, Length=363, Percent_Identity=31.129476584022, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322075, Length=365, Percent_Identity=29.041095890411, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS81_BURMA (Q62GE0)

Other databases:

- EMBL:   CP000010
- RefSeq:   YP_104234.1
- ProteinModelPortal:   Q62GE0
- SMR:   Q62GE0
- GeneID:   3091283
- GenomeReviews:   CP000010_GR
- KEGG:   bma:BMA2713
- TIGR:   BMA2713
- HOGENOM:   HBG646350
- OMA:   MDEAYQP
- PhylomeDB:   Q62GE0
- ProtClustDB:   PRK04870
- BioCyc:   BMAL243160:BMA_2713-MONOMER
- BRENDA:   2.6.1.9
- HAMAP:   MF_01023
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR01141

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.9

Molecular weight: Translated: 38142; Mature: 38011

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPA
CCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PRPAALIDRLRAVTGVPAACDVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSA
CCHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEHHHHH
KFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYPNNPTGTLYPDEDVERIIAAA
HHEEEEEEECCEECCCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
AASLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
HHHHEEEHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VRVPDAAAVFDVLLTERVLIKNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPEDIIRRDVLAMTGYPVPDATGFVKLDAMENPYSLPAPLAAELGERLAHVALNRYPA
CCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PRPAALIDRLRAVTGVPAACDVLLGNGSDEIISMLAMACAKPGAKVLAPVPGFVMYELSA
CCHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHHCCCCCCEECCCCCCEEHHHHH
KFAQLEFVGVPLRADLTLDIDAMLAALAEHRPALVYLAYPNNPTGTLYPDEDVERIIAAA
HHEEEEEEECCEECCCEECHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHH
AASLVVIDEAYQPFAQRSWLPRAAQFDNVVVMRTMSKLGLAGIRLGYLVGLPAWLVQFDK
HHHHEEEHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
VRPPYNVNVLTQAAAEFLLERVDVLDAQAAQLRDARTALAHAIGALPGATVFPSAGNFLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
VRVPDAAAVFDVLLTERVLIKNVSKMHPLLANCVRVTVGSPEENARLLAALKLALP
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA