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The map label for this gene is 126452287

Identifier: 126452287

GI number: 126452287

Start: 2876921

End: 2877844

Strand: Reverse

Name: 126452287

Synonym: BURPS1106A_2934

Alternate gene names: NA

Gene position: 2877844-2876921 (Counterclockwise)

Preceding gene: 126454665

Following gene: 126454045

Centisome position: 72.15

GC content: 67.86

Gene sequence:

>924_bases
ATGCCAACGGCCTTTTACACGCACCCCGACTGCCTGCTGCACGAGATGGGGGAGTGGCATCCCGAGTCGCCGGCGCGGCT
GTCGGCGATCCAGGATCAACTGATCGCGAGCCGCATCGACGACCTGATCGTCCACGAGACGGCGCCGTTCGCGAGCGAGA
CGGCGCTGGCCCGCGTGCATACGCAGGCGCACATCGATTACATCCGCAGCCGGATTCCGAAGGATGGGTACGTCGAGATC
GATCCCGACACGTCGCTGAACCGCTACACATGGCGCGCGGCGCTGCGCGCGGCCGGCGCGGCCGTCGAGGCGACGGACGC
GGTGCTCGAAGGCCGCTACGACAACGCGTTCTGCAGCGTGCGCCCGCCGGGCCATCATGCGGAACCCGCGCGCGCGATGG
GCTTCTGTTTCTTCAACAACGTCGCGATCGCCGCGCGCCACGCGCTCGAGATCCACGGCCTCGAGCGCGTCGCGATCATC
GATTTCGACGTCCATCACGGCAACGGCACCGAGGCCGCGTTCGCGAACGACGAGCGCGTGCTGATGTGCAGCTTCTTCCA
GCATCCGCTGTATCCGTTTTCGGGCGTCGACCACCAGGCGCCGAACATGGTCAATCTGCCGATGGCCGCGCGCACCAACG
GGATGGCGGTGCGCGAGGCGGTCGATCTGATGTGGCTGCCGCGGCTCGATGCGTTCAGGCCGCAGATGCTGTTCGTGTCG
GCGGGGTTCGATGCGCACCGCGAGGACGACATCGGCGGGATGGGGCTCGTCGAGGCCGACTACGAGTGGCTCACGCAGCA
GATCTGCGAAGTCGCGCGGAGGCATGCGCAAGGCCGGATCGTGAGCTGCCTCGAAGGCGGCTACAACCTGTCCGCGCTCG
GGCGAAGCGTGGTCGCGCATCTGCGCGTGCTCGCCGGCGTGTGA

Upstream 100 bases:

>100_bases
GTGATGTGGTAAGTTAGCGGCGAACTTCGCACCAGACGATATCGCGGACATCCTTGACGGAGACCTGCGGCGCGCATCGG
CCGCGTCGCGGAACGAGCTT

Downstream 100 bases:

>100_bases
ACGCGTCGCGTGTGCGCGGAGGGTGACGCGAGCGCCGGCGCCCCGCGCCCGGCCAGTGGGCGTCGGCCGCGCGGCATGCC
GCGACACACATCGGCGGATA

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MPTAFYTHPDCLLHEMGEWHPESPARLSAIQDQLIASRIDDLIVHETAPFASETALARVHTQAHIDYIRSRIPKDGYVEI
DPDTSLNRYTWRAALRAAGAAVEATDAVLEGRYDNAFCSVRPPGHHAEPARAMGFCFFNNVAIAARHALEIHGLERVAII
DFDVHHGNGTEAAFANDERVLMCSFFQHPLYPFSGVDHQAPNMVNLPMAARTNGMAVREAVDLMWLPRLDAFRPQMLFVS
AGFDAHREDDIGGMGLVEADYEWLTQQICEVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGV

Sequences:

>Translated_307_residues
MPTAFYTHPDCLLHEMGEWHPESPARLSAIQDQLIASRIDDLIVHETAPFASETALARVHTQAHIDYIRSRIPKDGYVEI
DPDTSLNRYTWRAALRAAGAAVEATDAVLEGRYDNAFCSVRPPGHHAEPARAMGFCFFNNVAIAARHALEIHGLERVAII
DFDVHHGNGTEAAFANDERVLMCSFFQHPLYPFSGVDHQAPNMVNLPMAARTNGMAVREAVDLMWLPRLDAFRPQMLFVS
AGFDAHREDDIGGMGLVEADYEWLTQQICEVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGV
>Mature_306_residues
PTAFYTHPDCLLHEMGEWHPESPARLSAIQDQLIASRIDDLIVHETAPFASETALARVHTQAHIDYIRSRIPKDGYVEID
PDTSLNRYTWRAALRAAGAAVEATDAVLEGRYDNAFCSVRPPGHHAEPARAMGFCFFNNVAIAARHALEIHGLERVAIID
FDVHHGNGTEAAFANDERVLMCSFFQHPLYPFSGVDHQAPNMVNLPMAARTNGMAVREAVDLMWLPRLDAFRPQMLFVSA
GFDAHREDDIGGMGLVEADYEWLTQQICEVARRHAQGRIVSCLEGGYNLSALGRSVVAHLRVLAGV

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=307, Percent_Identity=34.8534201954397, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI20070354, Length=327, Percent_Identity=35.1681957186544, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI17158039, Length=251, Percent_Identity=36.2549800796813, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI30795202, Length=251, Percent_Identity=36.2549800796813, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI30795204, Length=251, Percent_Identity=36.2549800796813, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI226529806, Length=326, Percent_Identity=34.0490797546012, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI153085395, Length=329, Percent_Identity=31.9148936170213, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI62750349, Length=238, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI62750347, Length=238, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI148539870, Length=234, Percent_Identity=36.7521367521368, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI169234807, Length=234, Percent_Identity=36.7521367521368, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI13128862, Length=274, Percent_Identity=22.2627737226277, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI293336691, Length=283, Percent_Identity=22.2614840989399, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI13128860, Length=284, Percent_Identity=22.1830985915493, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI217272877, Length=320, Percent_Identity=24.375, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=306, Percent_Identity=33.6601307189542, Blast_Score=151, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17540332, Length=306, Percent_Identity=33.6601307189542, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI193206283, Length=306, Percent_Identity=33.6601307189542, Blast_Score=151, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI193209491, Length=324, Percent_Identity=32.7160493827161, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17537347, Length=308, Percent_Identity=32.1428571428571, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI25154022, Length=282, Percent_Identity=34.0425531914894, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25154020, Length=283, Percent_Identity=34.2756183745583, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17534739, Length=279, Percent_Identity=26.1648745519713, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508561, Length=271, Percent_Identity=23.6162361623616, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324307, Length=318, Percent_Identity=32.0754716981132, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6325141, Length=287, Percent_Identity=25.0871080139373, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323999, Length=276, Percent_Identity=24.2753623188406, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321244, Length=263, Percent_Identity=24.7148288973384, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325325, Length=176, Percent_Identity=25, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24642142, Length=313, Percent_Identity=35.4632587859425, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24642144, Length=313, Percent_Identity=35.4632587859425, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360899, Length=313, Percent_Identity=35.4632587859425, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24642146, Length=313, Percent_Identity=35.4632587859425, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281360801, Length=330, Percent_Identity=31.2121212121212, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24641720, Length=330, Percent_Identity=31.2121212121212, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281360799, Length=330, Percent_Identity=31.2121212121212, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24644244, Length=275, Percent_Identity=22.5454545454545, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24657891, Length=276, Percent_Identity=24.6376811594203, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34020; Mature: 33889

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTAFYTHPDCLLHEMGEWHPESPARLSAIQDQLIASRIDDLIVHETAPFASETALARVH
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
TQAHIDYIRSRIPKDGYVEIDPDTSLNRYTWRAALRAAGAAVEATDAVLEGRYDNAFCSV
HHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEE
RPPGHHAEPARAMGFCFFNNVAIAARHALEIHGLERVAIIDFDVHHGNGTEAAFANDERV
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEECCCCEE
LMCSFFQHPLYPFSGVDHQAPNMVNLPMAARTNGMAVREAVDLMWLPRLDAFRPQMLFVS
EEEEHHCCCCCCCCCCCCCCCCEEECCHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEE
AGFDAHREDDIGGMGLVEADYEWLTQQICEVARRHAQGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LRVLAGV
HHHHHCC
>Mature Secondary Structure 
PTAFYTHPDCLLHEMGEWHPESPARLSAIQDQLIASRIDDLIVHETAPFASETALARVH
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
TQAHIDYIRSRIPKDGYVEIDPDTSLNRYTWRAALRAAGAAVEATDAVLEGRYDNAFCSV
HHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEE
RPPGHHAEPARAMGFCFFNNVAIAARHALEIHGLERVAIIDFDVHHGNGTEAAFANDERV
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEECCCCEE
LMCSFFQHPLYPFSGVDHQAPNMVNLPMAARTNGMAVREAVDLMWLPRLDAFRPQMLFVS
EEEEHHCCCCCCCCCCCCCCCCEEECCHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEEE
AGFDAHREDDIGGMGLVEADYEWLTQQICEVARRHAQGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCEEEEHHCCCCHHHHHHHHHHH
LRVLAGV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]