BacMap

Definition	Burkholderia pseudomallei 1106a chromosome I, complete genome.
Accession	NC_009076
Length	3,988,455

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The map label for this gene is fabG [H]

Identifier: 126452270

GI number: 126452270

Start: 1220216

End: 1220995

Strand: Direct

Name: fabG [H]

Synonym: BURPS1106A_1243

Alternate gene names: 126452270

Gene position: 1220216-1220995 (Clockwise)

Preceding gene: 126453267

Following gene: 126453334

Centisome position: 30.59

GC content: 72.82

Gene sequence:

>780_bases
ATGGATCTGGGAATCGCAGGACGGACCGCGCTCGTGTGCGCGGCCAGCAAGGGGCTCGGGCGCGGTTGCGCGCAGGCGCT
CGCCGCCGAGGGCGCGCGGCTCGTGATCGTCGCGCGCACGCGCGAGACGCTCGAGGCCGCCGCGGCCGATATTCGCGCGG
CGACGGGCGCCGACGTGACGGCCGTCGCGTGCGACATCACGACGCCCGAGGGGCGCGCGGCGGCGCTCGCCGCATGCCCG
CAGCCGGACATTCTCGTGACGAACGCGGGCGGCCCGCCGCCGGGCGACTTCCGCGATTTCACGCACGACGACTGGATTCG
CGCGCTCGAGGCGAACATGCTCACGCCGATCGAGCTGATCCGCGCGAGCGTCGACGGGATGATCGCGCGCCGCTTCGGGC
GCGTCGTCAACATCACGAGCTCGGCCGTGAAGGCGCCGATCGACGTGCTCGCGCTGTCCAACGGCGCGCGCTCGGGGCTC
ACGGGCTTCGTCGCGGGGCTCGCGCGCAAGGTGGCCGAGCACAACGTGACGATCAACAACCTGCTGCCGGGCCTCTTCGA
CACCGACCGGATCGCGACGACGCTCGCCGCGGCGGCGCAGGCGCAGGGCGCGACCGTCGACGAGCTGCGCGCGCGGCGCA
CGAAGGAAATTCCGGCGAAGCGCCTCGGCACGCCGCACGAGTTCGGCGCGGCGTGCGCGTTCCTCTGCAGTGTCCATGCG
GGCTACATCACCGGGCAGAACTGGCTGCTCGACGGCGGCGCGTATCCCGGCACATTTTGA

Upstream 100 bases:

>100_bases
CAGCGCGCGGGGGCGGCGGCAACGCGCGCATGCGGCGCGCGCCCCGCCGGCGGCCGTTTTCCGGTTTTCGTCACGCAGCC
ATCGACAAGGAACACGATTC

Downstream 100 bases:

>100_bases
AACCGATTTTGAAACCGATTTGAACCTGGCGGGCGCAGCCCGTAAAGTAGCGGGGTGGCACGTTCGCGCGCCGGCCGCCG
GCGGGCGCGGCACCGCGCGG

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDLGIAGRTALVCAASKGLGRGCAQALAAEGARLVIVARTRETLEAAAADIRAATGADVTAVACDITTPEGRAAALAACP
QPDILVTNAGGPPPGDFRDFTHDDWIRALEANMLTPIELIRASVDGMIARRFGRVVNITSSAVKAPIDVLALSNGARSGL
TGFVAGLARKVAEHNVTINNLLPGLFDTDRIATTLAAAAQAQGATVDELRARRTKEIPAKRLGTPHEFGAACAFLCSVHA
GYITGQNWLLDGGAYPGTF

Sequences:

>Translated_259_residues
MDLGIAGRTALVCAASKGLGRGCAQALAAEGARLVIVARTRETLEAAAADIRAATGADVTAVACDITTPEGRAAALAACP
QPDILVTNAGGPPPGDFRDFTHDDWIRALEANMLTPIELIRASVDGMIARRFGRVVNITSSAVKAPIDVLALSNGARSGL
TGFVAGLARKVAEHNVTINNLLPGLFDTDRIATTLAAAAQAQGATVDELRARRTKEIPAKRLGTPHEFGAACAFLCSVHA
GYITGQNWLLDGGAYPGTF
>Mature_259_residues
MDLGIAGRTALVCAASKGLGRGCAQALAAEGARLVIVARTRETLEAAAADIRAATGADVTAVACDITTPEGRAAALAACP
QPDILVTNAGGPPPGDFRDFTHDDWIRALEANMLTPIELIRASVDGMIARRFGRVVNITSSAVKAPIDVLALSNGARSGL
TGFVAGLARKVAEHNVTINNLLPGLFDTDRIATTLAAAAQAQGATVDELRARRTKEIPAKRLGTPHEFGAACAFLCSVHA
GYITGQNWLLDGGAYPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.1023622047244, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=27.4193548387097, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=26.8482490272374, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=27.6264591439689, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=27.906976744186, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371731, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI20149619, Length=188, Percent_Identity=29.2553191489362, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=230, Percent_Identity=23.0434782608696, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=26.7924528301887, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=25.4901960784314, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=32.5757575757576, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=31.7829457364341, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=27.906976744186, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=26.984126984127, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=25.0980392156863, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=26.5625, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789208, Length=261, Percent_Identity=29.1187739463602, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=30, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=25.6916996047431, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=24.5136186770428, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=256, Percent_Identity=28.90625, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=26.7716535433071, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=26.615969581749, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=28.4644194756554, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=26.6917293233083, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=26.3358778625954, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=25.7936507936508, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=25.5813953488372, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=26.1992619926199, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=26.8382352941176, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=24.8031496062992, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=24.1635687732342, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=26.7924528301887, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=26.3358778625954, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=26.8939393939394, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=26.2948207171315, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=26.8482490272374, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355319, Length=254, Percent_Identity=26.3779527559055, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24584744, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574402, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=29.1828793774319, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=28.4046692607004, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=25.968992248062, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21358495, Length=218, Percent_Identity=26.1467889908257, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26726; Mature: 26726

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGIAGRTALVCAASKGLGRGCAQALAAEGARLVIVARTRETLEAAAADIRAATGADVT
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCEE
AVACDITTPEGRAAALAACPQPDILVTNAGGPPPGDFRDFTHDDWIRALEANMLTPIELI
EEEEEECCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
RASVDGMIARRFGRVVNITSSAVKAPIDVLALSNGARSGLTGFVAGLARKVAEHNVTINN
HHHHHHHHHHHHCCEEEECHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHH
LLPGLFDTDRIATTLAAAAQAQGATVDELRARRTKEIPAKRLGTPHEFGAACAFLCSVHA
HCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHH
GYITGQNWLLDGGAYPGTF
CEEECCCEEEECCCCCCCC
>Mature Secondary Structure
MDLGIAGRTALVCAASKGLGRGCAQALAAEGARLVIVARTRETLEAAAADIRAATGADVT
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCEE
AVACDITTPEGRAAALAACPQPDILVTNAGGPPPGDFRDFTHDDWIRALEANMLTPIELI
EEEEEECCCCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
RASVDGMIARRFGRVVNITSSAVKAPIDVLALSNGARSGLTGFVAGLARKVAEHNVTINN
HHHHHHHHHHHHCCEEEECHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHH
LLPGLFDTDRIATTLAAAAQAQGATVDELRARRTKEIPAKRLGTPHEFGAACAFLCSVHA
HCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHH
GYITGQNWLLDGGAYPGTF
CEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]