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The map label for this gene is nrdR [H]

Identifier: 126452228

GI number: 126452228

Start: 3146618

End: 3147097

Strand: Reverse

Name: nrdR [H]

Synonym: BURPS1106A_3233

Alternate gene names: 126452228

Gene position: 3147097-3146618 (Counterclockwise)

Preceding gene: 126455099

Following gene: 126453015

Centisome position: 78.91

GC content: 65.83

Gene sequence:

>480_bases
ATGCGCTGCCCGTTCTGCCGGCACGACGATACTCAGGTGGTGGATTCGCGCGTGTCGGAAGACGGCGCCGCGATCCGCCG
GCGTCGGCGCTGCTCGGCCTGCGACAAGCGTTTCACGACGTATGAGCGGGTCGAGCTGGCGTTGCCGGCCGTCGTGAAGA
AAGACGGCAGTCGCACCGAATTCGACCGCCGCAAGATCGTCGCGAGCATGCAACTGGCGCTGCGCAAGCGCCCGGTTGCA
GCCGATGCGATCGACGCGGCGGTCGCCCGCATCGAATATCAACTGCTCGCCTCCGGCGAGCGCGAAGTCCGCAGTGAAAA
GCTCGGCGAACTCGTGATGAACGAGTTGCGCCAGCTCGACACGATCGCCTACGTGCGCTTCGCCTCTGTCTACCGGCGGT
TCGAAGACGTCTCCGAGTTCGAGGACGTGATCGAGGAATTCCGCCGCGCGGCGCCCGCGAAGACGCCTCGCAAGCGTTGA

Upstream 100 bases:

>100_bases
CGACGTGCTCGAGCATCCCGAAGACGCGGCGACGATCGAGCGCGTGCGTGCGCAGGTCGCCGAGCTGACGAAGCGTTTCC
CGGTCTATCGCTGATCGGCC

Downstream 100 bases:

>100_bases
GCTTGCGCATTCCGTTTCCCGTTTCGTTTTCCGTTCCATTCGTTTCTCCCGCGTAACACGCGGTGTGCGTGCTCGCCTGG
GCGATTGTCGTGTGCCCGGT

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELALPAVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAVARIEYQLLASGEREVRSEKLGELVMNELRQLDTIAYVRFASVYRRFEDVSEFEDVIEEFRRAAPAKTPRKR

Sequences:

>Translated_159_residues
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELALPAVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAVARIEYQLLASGEREVRSEKLGELVMNELRQLDTIAYVRFASVYRRFEDVSEFEDVIEEFRRAAPAKTPRKR
>Mature_159_residues
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELALPAVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAVARIEYQLLASGEREVRSEKLGELVMNELRQLDTIAYVRFASVYRRFEDVSEFEDVIEEFRRAAPAKTPRKR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=50.6944444444444, Blast_Score=157, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 18427; Mature: 18427

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELALPAVVKKDGSRTE
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
FDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLASGEREVRSEKLGELVMNELRQLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TIAYVRFASVYRRFEDVSEFEDVIEEFRRAAPAKTPRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELALPAVVKKDGSRTE
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
FDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLASGEREVRSEKLGELVMNELRQLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
TIAYVRFASVYRRFEDVSEFEDVIEEFRRAAPAKTPRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA