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The map label for this gene is serC-2 [H]

Identifier: 126452158

GI number: 126452158

Start: 2519813

End: 2520907

Strand: Reverse

Name: serC-2 [H]

Synonym: BURPS1106A_2565

Alternate gene names: 126452158

Gene position: 2520907-2519813 (Counterclockwise)

Preceding gene: 126454148

Following gene: 126453005

Centisome position: 63.21

GC content: 67.31

Gene sequence:

>1095_bases
ATGCATCGCAATCAACTGAATTTCTCCGGCGGCCCCGGCGCGCTGCCGGATACCGTGCTCGAACAGGTGCGGCAAGCGGT
GGTGGAGCTGCCGGAAACCGGCTTGTCGGTGCTCGGCATGAGCCATCGCTCGAGCTGGTTCTCGAGTCTGCTCGCGCAGG
CGCAGGCGGATCTGCGCGATCTGCTGGGCATTCCAGACGAGTACGGCGTCGTGTTCCTGCAAGGCGGCAGCAGCCTGCAG
TTCTCGATGATCCCGATGAATTTCTCGCGGCCGGGCGCGGCCGCGCCCGAGTACGTGACGACGGGCTACTGGGGCCGCAA
GGCGATCGGCGAGGCGTCGCGCGTGGCCGCGATGCGCGTGGTCTGGGACGGCGCGGCGAGCGGCTACCGGACGCTGCCGT
CGCTCGCCGCGCTCGACTGGGACGCGCGCGCGCCGTTTCGTCACTACGTATCCAACGAGACCGTCGAAGGGCTGCAGTTT
CCCGACGCGGCGGATCTGCCCGGCAGCCCGCTGATCGCGGACATGTCGTCGGATTTCATGTCGAGGCCGTTCGACGTGCG
CGCGTACGGCATGGTCTACGCGCACGCGCAGAAGAATCTCGGGCCTGCCGGCGTGACGGTCGCGATCATCCGGCGCGCGC
TGCTCGAGCGCGTTCCGGACACGCTGCCGCCGATGCTCGATTTCCGCACGCACGTCGAGCATCGGTCGAACTACAACACG
CCGCCCGTGTTCGCGATCTACGTGATGGCGCTCGTGCTGCGCTGGATTAGGGACGAAATCGGCGGCGTGCATGCGATGCG
CGACATCAATGCGCGCAAGGCCGCCATGCTCTATGCGACGCTCGATGCGTTGAACGAAGTGATCGACTGCCATGCGCACA
GGGCGGCGCGCTCGACGATGAACGTCGCGTTCCGTTTCAGGCAGCCGCGGCTCGACACGCTGTTCAAGGAGCAGTCCACG
GAGGCGGGCTTCTGCGGCCTGAGCGGGCACCGCTCGATCGGCGGCATCCGCGCGTCGCTCTACAACGCCGTATCGGAGCA
GGCGGTGAGCCGGCTGTGCACGTTCCTGAAGGACTTCGCGATCCGGCACGCGTGA

Upstream 100 bases:

>100_bases
CTGAACGCCGCGCTCAGGCGGGGCGCGACGCGTCCGTCCGCGGGCTATCTGCAGAAGTGATCCGATTCCGGTTCTCACCT
TGCCTCGGGAGTGTCGTCAG

Downstream 100 bases:

>100_bases
CGCGCGGCCGCGCGGCCGGCACCCGGCGCGCCGCCGCGCGCGTCGGCGCGGCACTTCGACGGCGTCGATTCAACCCGAAG
GAGATTGACCATGCTTTCCA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDEYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWGRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCTFLKDFAIRHA

Sequences:

>Translated_364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDEYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWGRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCTFLKDFAIRHA
>Mature_364_residues
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRDLLGIPDEYGVVFLQGGSSLQ
FSMIPMNFSRPGAAAPEYVTTGYWGRKAIGEASRVAAMRVVWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQF
PDAADLPGSPLIADMSSDFMSRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTMNVAFRFRQPRLDTLFKEQST
EAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCTFLKDFAIRHA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=367, Percent_Identity=39.5095367847411, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI10863955, Length=363, Percent_Identity=37.1900826446281, Blast_Score=239, Evalue=2e-63,
Organism=Escherichia coli, GI1787136, Length=361, Percent_Identity=38.781163434903, Blast_Score=254, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17506897, Length=364, Percent_Identity=37.9120879120879, Blast_Score=273, Evalue=1e-73,
Organism=Saccharomyces cerevisiae, GI6324758, Length=387, Percent_Identity=34.625322997416, Blast_Score=223, Evalue=4e-59,
Organism=Drosophila melanogaster, GI21356589, Length=360, Percent_Identity=40.2777777777778, Blast_Score=270, Evalue=1e-72,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40054; Mature: 40054

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLGIPDEYGVVFLQGGSSLQFSMIPMNFSRPGAAAPEYVTTGYWGRKAIGEASRVAAMRV
HHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCHHCCCCCHHHHCHHHHHHHHHH
VWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQFPDAADLPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
SRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCCCEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTM
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQPRLDTLFKEQSTEAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCTFLKDFA
HHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRHA
HCCC
>Mature Secondary Structure
MHRNQLNFSGGPGALPDTVLEQVRQAVVELPETGLSVLGMSHRSSWFSSLLAQAQADLRD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
LLGIPDEYGVVFLQGGSSLQFSMIPMNFSRPGAAAPEYVTTGYWGRKAIGEASRVAAMRV
HHCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCHHCCCCCHHHHCHHHHHHHHHH
VWDGAASGYRTLPSLAALDWDARAPFRHYVSNETVEGLQFPDAADLPGSPLIADMSSDFM
EECCCCCCHHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEECCCHHHHH
SRPFDVRAYGMVYAHAQKNLGPAGVTVAIIRRALLERVPDTLPPMLDFRTHVEHRSNYNT
CCCCCEEHHHHEEEHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
PPVFAIYVMALVLRWIRDEIGGVHAMRDINARKAAMLYATLDALNEVIDCHAHRAARSTM
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVAFRFRQPRLDTLFKEQSTEAGFCGLSGHRSIGGIRASLYNAVSEQAVSRLCTFLKDFA
HHHHEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRHA
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA