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The map label for this gene is rhmD [H]

Identifier: 126452147

GI number: 126452147

Start: 769583

End: 770683

Strand: Direct

Name: rhmD [H]

Synonym: BURPS1106A_0785

Alternate gene names: 126452147

Gene position: 769583-770683 (Clockwise)

Preceding gene: 126452059

Following gene: 126453872

Centisome position: 19.3

GC content: 73.84

Gene sequence:

>1101_bases
ATGAAACCGTTTTCCGAACCGATCATCCGCTGCGCGAAGGCGCGCGCTTACCGCATTCCGACGGACCGGCCCGAGGCGGA
CGGCACGTTCGCGTGGACGGACACGACGATCGTCGTCGCGACGCTCGACGCGGGCGACGCGCACGGCATCGGCTACACGT
ACACCGACGCGAGCGCTGCCGCGCTGATCGAGCGGATGCTCGCGCCGGCGCTCGACGGGCGCAGCGCGTTCGACATCGGC
GGCGCGCTCGCCGCGCTGCGGCGCGCGGTCCGCAACGTCGGCCGCGGCGGCGTCGCGGCCACGGCGATATCGGCGCTCGA
CGCCGCGCTGTGGGACGCGAAGGCGAAGCTGCTCGGCCTGCCGCTCGCGAAGCTGCTCGGCGGCGTGCGCGACGCGGTGC
CCGTGTACGGCAGCGGCGGCTTCACGAGCTACGACGAGCACGCGTTGCGCGCGCAGCTCGAAGGCTGGCGCGCGCAGGGG
CTGCACGCGTGCAAGATCAAGGTCGGCAGCGCGCCGCGCGACGATCCGGCGCGCGTGCGCATCGCGCGCGACGCGCTCGG
CGGCGGCGTCGCGCTGTTCGTCGACGCGAACGGCGCGTTCGCGCCGCGCGATGCGCTCGCGTTCGCGCAGCGCATCGCCG
AGTGCGACGTGCGCTGGTTCGAGGAGCCGGTGAGCGCCGACGACATCGACGGCCTGCGCTTCGTGCGCGAACGGCTCGCC
GCGGGCGTCGACGTCGCGGCGGGCGAGTACGGCTATACGCTCGACGACTTTCGCGTCTTGCTCGCGTCGGGCGCGCTCGA
CGTGCTGCAGGCGGACGCCACGCGCTGCGGCGGCGTGAGCGGCTTTCTCGAGGCCGCGACGCTCGCCGACGCGTTTCATC
GCGACCTGTCCGCGCATTGCGCGCCCGCGCTGCACCGGCACGTGTGCTGCGCGGCGCCGCGGGTGCGGCACGTCGAGTGG
TTTCACGATCATGCGCGAATCGAGCGGATGCTGTTCGACGGTGCGCCGACGCCGCGCGACGGCGCGATCGCGCCGGACAT
GTCGCGGCCCGGGCTCGGCATCGAGCTGAAAGCGCAGGACGCGGCGCGCTTTGCGGTCTGA

Upstream 100 bases:

>100_bases
GACGCATGAGCGACGGGTATGCGGATTGCGCGCGGGGTGACGTCGGCGCTGGCGGTACGAGGTCGGGCGGCGCGCGATCG
AATCGAACGATGCCATCACG

Downstream 100 bases:

>100_bases
CGCCGGTCGGTGCGCGCACGCGCCGCGCGCTTCGCATGCGTTGCGCGCGCAAGCGGCGCGCATTCCGCATTCGGCGGCGG
GCCGGCATCGCGGCGTACGA

Product: mandelate racemase/muconate lactonizing enzyme

Products: NA

Alternate protein names: RhamD [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MKPFSEPIIRCAKARAYRIPTDRPEADGTFAWTDTTIVVATLDAGDAHGIGYTYTDASAAALIERMLAPALDGRSAFDIG
GALAALRRAVRNVGRGGVAATAISALDAALWDAKAKLLGLPLAKLLGGVRDAVPVYGSGGFTSYDEHALRAQLEGWRAQG
LHACKIKVGSAPRDDPARVRIARDALGGGVALFVDANGAFAPRDALAFAQRIAECDVRWFEEPVSADDIDGLRFVRERLA
AGVDVAAGEYGYTLDDFRVLLASGALDVLQADATRCGGVSGFLEAATLADAFHRDLSAHCAPALHRHVCCAAPRVRHVEW
FHDHARIERMLFDGAPTPRDGAIAPDMSRPGLGIELKAQDAARFAV

Sequences:

>Translated_366_residues
MKPFSEPIIRCAKARAYRIPTDRPEADGTFAWTDTTIVVATLDAGDAHGIGYTYTDASAAALIERMLAPALDGRSAFDIG
GALAALRRAVRNVGRGGVAATAISALDAALWDAKAKLLGLPLAKLLGGVRDAVPVYGSGGFTSYDEHALRAQLEGWRAQG
LHACKIKVGSAPRDDPARVRIARDALGGGVALFVDANGAFAPRDALAFAQRIAECDVRWFEEPVSADDIDGLRFVRERLA
AGVDVAAGEYGYTLDDFRVLLASGALDVLQADATRCGGVSGFLEAATLADAFHRDLSAHCAPALHRHVCCAAPRVRHVEW
FHDHARIERMLFDGAPTPRDGAIAPDMSRPGLGIELKAQDAARFAV
>Mature_366_residues
MKPFSEPIIRCAKARAYRIPTDRPEADGTFAWTDTTIVVATLDAGDAHGIGYTYTDASAAALIERMLAPALDGRSAFDIG
GALAALRRAVRNVGRGGVAATAISALDAALWDAKAKLLGLPLAKLLGGVRDAVPVYGSGGFTSYDEHALRAQLEGWRAQG
LHACKIKVGSAPRDDPARVRIARDALGGGVALFVDANGAFAPRDALAFAQRIAECDVRWFEEPVSADDIDGLRFVRERLA
AGVDVAAGEYGYTLDDFRVLLASGALDVLQADATRCGGVSGFLEAATLADAFHRDLSAHCAPALHRHVCCAAPRVRHVEW
FHDHARIERMLFDGAPTPRDGAIAPDMSRPGLGIELKAQDAARFAV

Specific function: Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR) [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=401, Percent_Identity=23.4413965087282, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI186972148, Length=258, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI226510960, Length=338, Percent_Identity=26.0355029585799, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI48994953, Length=297, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.90 [H]

Molecular weight: Translated: 38806; Mature: 38806

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00908 MR_MLE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFSEPIIRCAKARAYRIPTDRPEADGTFAWTDTTIVVATLDAGDAHGIGYTYTDASAA
CCCHHHHHHHHHHHCEEECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEECCHHHH
ALIERMLAPALDGRSAFDIGGALAALRRAVRNVGRGGVAATAISALDAALWDAKAKLLGL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PLAKLLGGVRDAVPVYGSGGFTSYDEHALRAQLEGWRAQGLHACKIKVGSAPRDDPARVR
CHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCEEEEEEEECCCCCCCHHHEE
IARDALGGGVALFVDANGAFAPRDALAFAQRIAECDVRWFEEPVSADDIDGLRFVRERLA
EEHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AGVDVAAGEYGYTLDDFRVLLASGALDVLQADATRCGGVSGFLEAATLADAFHRDLSAHC
CCCEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
APALHRHVCCAAPRVRHVEWFHDHARIERMLFDGAPTPRDGAIAPDMSRPGLGIELKAQD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCC
AARFAV
CHHCCC
>Mature Secondary Structure
MKPFSEPIIRCAKARAYRIPTDRPEADGTFAWTDTTIVVATLDAGDAHGIGYTYTDASAA
CCCHHHHHHHHHHHCEEECCCCCCCCCCEEEEECCEEEEEEECCCCCCCCCEEECCHHHH
ALIERMLAPALDGRSAFDIGGALAALRRAVRNVGRGGVAATAISALDAALWDAKAKLLGL
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
PLAKLLGGVRDAVPVYGSGGFTSYDEHALRAQLEGWRAQGLHACKIKVGSAPRDDPARVR
CHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCEEEEEEEECCCCCCCHHHEE
IARDALGGGVALFVDANGAFAPRDALAFAQRIAECDVRWFEEPVSADDIDGLRFVRERLA
EEHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AGVDVAAGEYGYTLDDFRVLLASGALDVLQADATRCGGVSGFLEAATLADAFHRDLSAHC
CCCEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
APALHRHVCCAAPRVRHVEWFHDHARIERMLFDGAPTPRDGAIAPDMSRPGLGIELKAQD
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCC
AARFAV
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA