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The map label for this gene is uup-A [H]

Identifier: 126452112

GI number: 126452112

Start: 1122571

End: 1124553

Strand: Direct

Name: uup-A [H]

Synonym: BURPS1106A_1144

Alternate gene names: 126452112

Gene position: 1122571-1124553 (Clockwise)

Preceding gene: 126453665

Following gene: 126455235

Centisome position: 28.15

GC content: 68.94

Gene sequence:

>1983_bases
ATGGGCGCTTCCGATTTTTTCTCCGCCGTCTTCCCCATGTCGCTTTATTCCATTACCGGCGCGCAACTCGCGTTCGGCCA
CGTCGCGCTGCTCGATCACGCGGACTTCTCGCTCGAAGCTGGCGAGCGCGTCGGGCTCATCGGCCGCAACGGCGCCGGCA
AGTCGTCGCTGCTGAAGATCGTCGCGGATCTGGCGAAACCCGACGACGGCCTCGTCACGCGGCAGCAGCACCTCGTGACG
GTCTATGTGCCGCAGGAGCCGGAATTCGTCGCCGGGCAGACGGTGTTCGACGCGGTGGCCTCCGGGCTGACCGATACGCG
CGCGCTGCTCGCCGAATACGACGAGATCGCGCACCGGCTCGCCGATACGCCCGAGGGCGCCGAGCACGACGCGCTGCTTG
CGCGGATGAACGCGCTGCAATCGTCGCTCGACGCGACGGACGCGTGGAACTGGCGCACGCGGGTGGCGACGACGCTCGCG
CAGATCGGGCTCGACGGCGATACGAAGATCGACGCGCTGTCGGGCGGGATGCAGAAGCGCGCCGCGCTCGCGCGCGCGCT
CGTCGTGCAGCCGGACGTGCTGCTCCTCGACGAGCCGACCAACCATCTCGATTTCGACGGCATTCGCTGGCTCGAGGAAC
TGCTCGTCGCGCAGCGCGCGGGCCTGTTCTTCATCACGCACGATCGCGCGTTTCTCGATCGCGTCGCGACGCGCATCGTC
GAGCTCGACCGCGGCCGCCTGCTGTCGTATCCGGGCAACTTCTCCGCGTATCAGACGCGCAAGGCGCAGCAGCTCGAGGT
CGAGCGCGTCGAGAACGAGAAGTTCGACAAGCTGCTCGCGCAGGAGGAGGTGTGGATCCGCAAGGGCGTCGAGGCGCGGC
GCACGCGCAGCGTCGGCCGCGTCGCGCGGCTCGAGCAGATGCGCCGCGAGCGCGCGGAGCGCCGCAACGCGCAAGGCAAC
GTGAGGCTCGACGTCGCGCAGGGCGAGAAATCGGGCAAGATCGTCGCGGAGCTGACCGACGTGACGAAGCGCTACGGCGA
GCGCACGGTCGTCGAGCGCTTCTCGGCCACGGTGATGCGCGGCGACAAGATCGGCTTCGTCGGCCCGAACGGCGCGGGCA
AGACCACGCTGCTCAAGCTGATCCTCGGCGAACTGAAGCCCGACGCGGGCACGGTGCGCACGGGCACGAACCTGCAGGTC
GCGTATTTCGACCAGATGCGCGCGCAACTCGATCAGGAGAAGAGCCTCGCGGACACGATCAGCCCCGGCAGCGAGTGGGT
CGAGATCGGCGGCGTGCGCAAGCACGTGATGAGCTATCTGGGCGACTTCCTGTTCGCGCCCGAGCGCGCGCGCTCGCCCG
TCAAGTCGCTGTCGGGCGGCGAGCGCAACCGGCTGCTGCTCGCGCGCCTGTTCGCGCGCCCAGCCAACGTGCTCGTGCTC
GACGAGCCGACCAACGACCTCGACATCCCGACGCTCGAACTGCTCGAAGAGCTGCTGACCGATTACGACGGCACGGTGCT
GCTCGTCAGCCACGATCGTGCGTTTCTCGACAACGTCGTCACGTCGGTGATCGCCTCGGAGGGCAACGGCCTGTGGCGCG
AATACGTCGGCGGCTTCACCGATTGGCAGATCCAGCGCGAGCGCGCGCAGCGGATCGCGCACGAGGAGGCGGCCAAGCGC
GCGGCGAAGGAGCCCGCGAGCGCGAAGGATGACGCGCCCAAGGGCGCGGCGGGCCGCAATGCGCAGCGCACGGTCAAGCT
GTCGTTCAACGAGCAGCGCGAGCTCGACGCGCTGCCCGCGAGGATCGCGGCGCTCGAGGCCGAGCAGAAGGCGATTGCCG
CGCAGCTCGAGGACGGCTCGATCTTCTCGAAGGATCCGCAGGAGGGCACGCGCCTGACCGAGCGCTTCGCGGCGCTCGAC
GACGAGCTGCTCGCGGCGCTGGAGCGCTGGGAGGCGCTCGAGGCGAAACGTAAGCCTTCATGA

Upstream 100 bases:

>100_bases
CCCGCCAGCCCGCGCCGCCGGTCGCCGCGCGCGCGCCGGCGTTGCGCGTTTCGCGCCCGGCCATTGTGCCGTATCGGCGC
CGTGCGCCGCCCCCGGTACA

Downstream 100 bases:

>100_bases
GCCCGCCGTTGCGGAACCAGTAAAATACGCCGCGCTCCGGGCGACGCATCGCGCGGCCGTCGGGCGCGGCGCGCCGCCCG
CTTTCGGAGCAATGCGAGCA

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MGASDFFSAVFPMSLYSITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVADLAKPDDGLVTRQQHLVT
VYVPQEPEFVAGQTVFDAVASGLTDTRALLAEYDEIAHRLADTPEGAEHDALLARMNALQSSLDATDAWNWRTRVATTLA
QIGLDGDTKIDALSGGMQKRAALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVAQRAGLFFITHDRAFLDRVATRIV
ELDRGRLLSYPGNFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRVARLEQMRRERAERRNAQGN
VRLDVAQGEKSGKIVAELTDVTKRYGERTVVERFSATVMRGDKIGFVGPNGAGKTTLLKLILGELKPDAGTVRTGTNLQV
AYFDQMRAQLDQEKSLADTISPGSEWVEIGGVRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVL
DEPTNDLDIPTLELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEGNGLWREYVGGFTDWQIQRERAQRIAHEEAAKR
AAKEPASAKDDAPKGAAGRNAQRTVKLSFNEQRELDALPARIAALEAEQKAIAAQLEDGSIFSKDPQEGTRLTERFAALD
DELLAALERWEALEAKRKPS

Sequences:

>Translated_660_residues
MGASDFFSAVFPMSLYSITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVADLAKPDDGLVTRQQHLVT
VYVPQEPEFVAGQTVFDAVASGLTDTRALLAEYDEIAHRLADTPEGAEHDALLARMNALQSSLDATDAWNWRTRVATTLA
QIGLDGDTKIDALSGGMQKRAALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVAQRAGLFFITHDRAFLDRVATRIV
ELDRGRLLSYPGNFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRVARLEQMRRERAERRNAQGN
VRLDVAQGEKSGKIVAELTDVTKRYGERTVVERFSATVMRGDKIGFVGPNGAGKTTLLKLILGELKPDAGTVRTGTNLQV
AYFDQMRAQLDQEKSLADTISPGSEWVEIGGVRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVL
DEPTNDLDIPTLELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEGNGLWREYVGGFTDWQIQRERAQRIAHEEAAKR
AAKEPASAKDDAPKGAAGRNAQRTVKLSFNEQRELDALPARIAALEAEQKAIAAQLEDGSIFSKDPQEGTRLTERFAALD
DELLAALERWEALEAKRKPS
>Mature_659_residues
GASDFFSAVFPMSLYSITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKIVADLAKPDDGLVTRQQHLVTV
YVPQEPEFVAGQTVFDAVASGLTDTRALLAEYDEIAHRLADTPEGAEHDALLARMNALQSSLDATDAWNWRTRVATTLAQ
IGLDGDTKIDALSGGMQKRAALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVAQRAGLFFITHDRAFLDRVATRIVE
LDRGRLLSYPGNFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGRVARLEQMRRERAERRNAQGNV
RLDVAQGEKSGKIVAELTDVTKRYGERTVVERFSATVMRGDKIGFVGPNGAGKTTLLKLILGELKPDAGTVRTGTNLQVA
YFDQMRAQLDQEKSLADTISPGSEWVEIGGVRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVLD
EPTNDLDIPTLELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEGNGLWREYVGGFTDWQIQRERAQRIAHEEAAKRA
AKEPASAKDDAPKGAAGRNAQRTVKLSFNEQRELDALPARIAALEAEQKAIAAQLEDGSIFSKDPQEGTRLTERFAALDD
ELLAALERWEALEAKRKPS

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=547, Percent_Identity=33.6380255941499, Blast_Score=219, Evalue=7e-57,
Organism=Homo sapiens, GI27881506, Length=524, Percent_Identity=31.1068702290076, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI10947137, Length=524, Percent_Identity=31.1068702290076, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI10947135, Length=533, Percent_Identity=30.3939962476548, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI69354671, Length=502, Percent_Identity=31.4741035856574, Blast_Score=180, Evalue=5e-45,
Organism=Escherichia coli, GI1787182, Length=644, Percent_Identity=47.5155279503106, Blast_Score=546, Evalue=1e-156,
Organism=Escherichia coli, GI2367384, Length=539, Percent_Identity=35.9925788497217, Blast_Score=336, Evalue=3e-93,
Organism=Escherichia coli, GI1787041, Length=514, Percent_Identity=31.5175097276265, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1789751, Length=618, Percent_Identity=30.0970873786408, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1788165, Length=189, Percent_Identity=34.3915343915344, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789891, Length=251, Percent_Identity=27.4900398406374, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI48995001, Length=536, Percent_Identity=24.8134328358209, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=32.8767123287671, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787792, Length=528, Percent_Identity=23.4848484848485, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1789873, Length=222, Percent_Identity=31.981981981982, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786872, Length=229, Percent_Identity=27.0742358078603, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787758, Length=190, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788761, Length=226, Percent_Identity=28.3185840707965, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=186, Percent_Identity=31.1827956989247, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788644, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081791, Length=208, Percent_Identity=26.9230769230769, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786345, Length=197, Percent_Identity=31.9796954314721, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=590, Percent_Identity=28.9830508474576, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17553372, Length=509, Percent_Identity=32.4165029469548, Blast_Score=195, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17555318, Length=514, Percent_Identity=28.988326848249, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320874, Length=530, Percent_Identity=29.811320754717, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6321121, Length=545, Percent_Identity=30.2752293577982, Blast_Score=194, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6325030, Length=397, Percent_Identity=28.9672544080605, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6323278, Length=400, Percent_Identity=27, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6324314, Length=399, Percent_Identity=27.3182957393484, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24666836, Length=545, Percent_Identity=32.2935779816514, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24642252, Length=555, Percent_Identity=30.2702702702703, Blast_Score=205, Evalue=9e-53,
Organism=Drosophila melanogaster, GI18859989, Length=555, Percent_Identity=30.2702702702703, Blast_Score=205, Evalue=9e-53,
Organism=Drosophila melanogaster, GI24641342, Length=536, Percent_Identity=28.3582089552239, Blast_Score=197, Evalue=2e-50,
Organism=Drosophila melanogaster, GI221500365, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007184, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72853; Mature: 72722

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASDFFSAVFPMSLYSITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKI
CCCHHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHH
VADLAKPDDGLVTRQQHLVTVYVPQEPEFVAGQTVFDAVASGLTDTRALLAEYDEIAHRL
HHHHCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ADTPEGAEHDALLARMNALQSSLDATDAWNWRTRVATTLAQIGLDGDTKIDALSGGMQKR
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHH
AALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVAQRAGLFFITHDRAFLDRVATRIV
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
ELDRGRLLSYPGNFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGR
HHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VARLEQMRRERAERRNAQGNVRLDVAQGEKSGKIVAELTDVTKRYGERTVVERFSATVMR
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHC
GDKIGFVGPNGAGKTTLLKLILGELKPDAGTVRTGTNLQVAYFDQMRAQLDQEKSLADTI
CCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHC
SPGSEWVEIGGVRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVL
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEE
DEPTNDLDIPTLELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEGNGLWREYVGGFT
ECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCC
DWQIQRERAQRIAHEEAAKRAAKEPASAKDDAPKGAAGRNAQRTVKLSFNEQRELDALPA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
RIAALEAEQKAIAAQLEDGSIFSKDPQEGTRLTERFAALDDELLAALERWEALEAKRKPS
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GASDFFSAVFPMSLYSITGAQLAFGHVALLDHADFSLEAGERVGLIGRNGAGKSSLLKI
CCHHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHH
VADLAKPDDGLVTRQQHLVTVYVPQEPEFVAGQTVFDAVASGLTDTRALLAEYDEIAHRL
HHHHCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ADTPEGAEHDALLARMNALQSSLDATDAWNWRTRVATTLAQIGLDGDTKIDALSGGMQKR
HCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCHHHH
AALARALVVQPDVLLLDEPTNHLDFDGIRWLEELLVAQRAGLFFITHDRAFLDRVATRIV
HHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
ELDRGRLLSYPGNFSAYQTRKAQQLEVERVENEKFDKLLAQEEVWIRKGVEARRTRSVGR
HHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VARLEQMRRERAERRNAQGNVRLDVAQGEKSGKIVAELTDVTKRYGERTVVERFSATVMR
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHC
GDKIGFVGPNGAGKTTLLKLILGELKPDAGTVRTGTNLQVAYFDQMRAQLDQEKSLADTI
CCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHHHHHC
SPGSEWVEIGGVRKHVMSYLGDFLFAPERARSPVKSLSGGERNRLLLARLFARPANVLVL
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHCCCCCEEEE
DEPTNDLDIPTLELLEELLTDYDGTVLLVSHDRAFLDNVVTSVIASEGNGLWREYVGGFT
ECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCC
DWQIQRERAQRIAHEEAAKRAAKEPASAKDDAPKGAAGRNAQRTVKLSFNEQRELDALPA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHH
RIAALEAEQKAIAAQLEDGSIFSKDPQEGTRLTERFAALDDELLAALERWEALEAKRKPS
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]