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The map label for this gene is cysS

Identifier: 126452065

GI number: 126452065

Start: 2561731

End: 2563128

Strand: Reverse

Name: cysS

Synonym: BURPS1106A_2596

Alternate gene names: 126452065

Gene position: 2563128-2561731 (Counterclockwise)

Preceding gene: 126454157

Following gene: 126455439

Centisome position: 64.26

GC content: 65.31

Gene sequence:

>1398_bases
ATGGAATCACTGCGCATCTACAACACGCTCGCGCGTGACAAGCAAGACTTCGTGCCGCGGCAGCCCGGCGAAGTGCGGAT
GTACGTCTGCGGGATCACCGTCTACGACTATTGCCACATCGGCCATGCGCGGATGGTGGTCGTGTTCGACATCGTCCAGC
GCTGGTTGCGCGCGCGCGGCTATCGCGTGACATACGTGCGCAACATCACCGACATCGACGACAAGATCATCCGCCGCGCG
GTCGAGAACGGCGAGACGATCCAGTCGCTCACGCGCCGCTTCACCGACGCGATGAACGCGGATTTCGACGCGCTCGGCGT
CGAGCGGCCGGACCTCGAGCCGCGCGCGACCGAGTTCATCCCGCAGATGCTCGGGATGATCGAGAAGCTCGAGGCGAACG
GTTACGCGTATCAGGCGAAGGACGGCGACGTCAACTATTCGGTGCGCAAGTTCGCGAACTACGGCAGGCTCTCCGGCAAG
TCGCTCGAGGATTTGCGCGCGGGCGAGCGCGTCGCCGCGAACGATGCGAAGGAGGATCCGCTCGACTTCGTGCTGTGGAA
GCGCGCGAAGCCGCAGGAGCCGGCGGGCGCGTCGTGGGAATCGAAGTACGGCGCGGGCCGCCCGGGCTGGCACATCGAAT
GTTCGGCGATGGGCTGCACGCTGCTCGGCGCACACTTCGACATTCACGGCGGCGGCCAGGACCTGCAGTTCCCGCATCAC
GAGAACGAGATCGCGCAAAGCGAGGGTGCGACCGGACAAACTTTCGTCAATTATTGGATGCACAACGGTTTCGTGCAGGT
CGATAGTGAGAAGATGTCGAAGTCGCTCGGCAACTTCTTCACGATCCGCGAAGTGCTCGAGAAGTTCGACGCCGAGGTCG
TGCGCTTCTTCATCGTTCGCACGCATTACCGTTCGCCGCTCAACTACAGCGACGTTCATCTCGACGACGCGCGCGCATCG
CTCACGCGCCTTTACACGGCATTGAAGGACGCGACGCCGGATGCGCAGCCGCTCGACTGGAGCGAGGCGCACGCGCAGCG
TTTCGCCGCCGCGATGAACGACGATTTCAACACGGCGGTCGCCGTCGCCGTGCTGTTCGAGCTCGCGACCGAGGTGAACC
GCACACGCGAGCCGGCGCTCGCGCGCCAGCTCAGGCTGCTTGCGGGCCTGCTCGGCCTGCTCGGCCGCGAGCCGCGCGAA
TTCCTGCAGCACGCGGCGGGCGCCGCGCGCACGGGCGCGCTCGAGCCGCATGAGATCGAAGCGAGGATCGCCGCGCGCGT
CGCGGCGAAACAGGCGAAGAACTATGCCGAAGCGGACCGGATCCGCGCGGAATTGCTCGAAGCCGGAATCGCACTTGAAG
ACAAACCGGGCGGATCGACGGAGTGGCGCCGCGTATGA

Upstream 100 bases:

>100_bases
GAGGAAGCGCACGGCACGCGGCCCCAGCCAGAAATCCTGTCGGGTGCCGCAGGCACGGCGAGCATCGCCAGGCGGTTTCC
TTCGGCTCACTTTCGTCTCT

Downstream 100 bases:

>100_bases
GCGCGCATCGTCTGTCCCGCTGATCGATTCGCCAGGTAGGAGGCTAGATGGCAACGGCCAGAAAAGCGCCGGCTAAGCGT
GCGGCGTCGCAGCCGCCGAT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MESLRIYNTLARDKQDFVPRQPGEVRMYVCGITVYDYCHIGHARMVVVFDIVQRWLRARGYRVTYVRNITDIDDKIIRRA
VENGETIQSLTRRFTDAMNADFDALGVERPDLEPRATEFIPQMLGMIEKLEANGYAYQAKDGDVNYSVRKFANYGRLSGK
SLEDLRAGERVAANDAKEDPLDFVLWKRAKPQEPAGASWESKYGAGRPGWHIECSAMGCTLLGAHFDIHGGGQDLQFPHH
ENEIAQSEGATGQTFVNYWMHNGFVQVDSEKMSKSLGNFFTIREVLEKFDAEVVRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDATPDAQPLDWSEAHAQRFAAAMNDDFNTAVAVAVLFELATEVNRTREPALARQLRLLAGLLGLLGREPRE
FLQHAAGAARTGALEPHEIEARIAARVAAKQAKNYAEADRIRAELLEAGIALEDKPGGSTEWRRV

Sequences:

>Translated_465_residues
MESLRIYNTLARDKQDFVPRQPGEVRMYVCGITVYDYCHIGHARMVVVFDIVQRWLRARGYRVTYVRNITDIDDKIIRRA
VENGETIQSLTRRFTDAMNADFDALGVERPDLEPRATEFIPQMLGMIEKLEANGYAYQAKDGDVNYSVRKFANYGRLSGK
SLEDLRAGERVAANDAKEDPLDFVLWKRAKPQEPAGASWESKYGAGRPGWHIECSAMGCTLLGAHFDIHGGGQDLQFPHH
ENEIAQSEGATGQTFVNYWMHNGFVQVDSEKMSKSLGNFFTIREVLEKFDAEVVRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDATPDAQPLDWSEAHAQRFAAAMNDDFNTAVAVAVLFELATEVNRTREPALARQLRLLAGLLGLLGREPRE
FLQHAAGAARTGALEPHEIEARIAARVAAKQAKNYAEADRIRAELLEAGIALEDKPGGSTEWRRV
>Mature_465_residues
MESLRIYNTLARDKQDFVPRQPGEVRMYVCGITVYDYCHIGHARMVVVFDIVQRWLRARGYRVTYVRNITDIDDKIIRRA
VENGETIQSLTRRFTDAMNADFDALGVERPDLEPRATEFIPQMLGMIEKLEANGYAYQAKDGDVNYSVRKFANYGRLSGK
SLEDLRAGERVAANDAKEDPLDFVLWKRAKPQEPAGASWESKYGAGRPGWHIECSAMGCTLLGAHFDIHGGGQDLQFPHH
ENEIAQSEGATGQTFVNYWMHNGFVQVDSEKMSKSLGNFFTIREVLEKFDAEVVRFFIVRTHYRSPLNYSDVHLDDARAS
LTRLYTALKDATPDAQPLDWSEAHAQRFAAAMNDDFNTAVAVAVLFELATEVNRTREPALARQLRLLAGLLGLLGREPRE
FLQHAAGAARTGALEPHEIEARIAARVAAKQAKNYAEADRIRAELLEAGIALEDKPGGSTEWRRV

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI13375695, Length=387, Percent_Identity=39.0180878552972, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI21269877, Length=361, Percent_Identity=33.7950138504155, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI303304987, Length=361, Percent_Identity=33.7950138504155, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI62240992, Length=361, Percent_Identity=33.7950138504155, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI10835051, Length=361, Percent_Identity=33.7950138504155, Blast_Score=184, Evalue=2e-46,
Organism=Escherichia coli, GI1786737, Length=467, Percent_Identity=55.8886509635974, Blast_Score=491, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17509795, Length=258, Percent_Identity=36.046511627907, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17509797, Length=258, Percent_Identity=36.046511627907, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=443, Percent_Identity=30.9255079006772, Blast_Score=192, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19922218, Length=504, Percent_Identity=34.5238095238095, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI19922364, Length=338, Percent_Identity=34.0236686390533, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYC_BURM7 (A3ML43)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001080979.1
- ProteinModelPortal:   A3ML43
- SMR:   A3ML43
- GeneID:   4892996
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_1432
- TIGR:   BMA10247_1432
- HOGENOM:   HBG327651
- OMA:   DFDALNM
- ProtClustDB:   PRK00260
- BioCyc:   BMAL320389:BMA10247_1432-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00041_B
- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10890
- PRINTS:   PR00983
- SMART:   SM00840
- TIGRFAMs:   TIGR00435

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.16

Molecular weight: Translated: 52367; Mature: 52367

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 274-274

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLRIYNTLARDKQDFVPRQPGEVRMYVCGITVYDYCHIGHARMVVVFDIVQRWLRARG
CCCHHHHHHHHCCHHHCCCCCCCCEEEEEECEEHHHHHHCCCHHHHHHHHHHHHHHHHCC
YRVTYVRNITDIDDKIIRRAVENGETIQSLTRRFTDAMNADFDALGVERPDLEPRATEFI
CEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHH
PQMLGMIEKLEANGYAYQAKDGDVNYSVRKFANYGRLSGKSLEDLRAGERVAANDAKEDP
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKRAKPQEPAGASWESKYGAGRPGWHIECSAMGCTLLGAHFDIHGGGQDLQFPHH
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECEEEECCCCCCCCCCCC
ENEIAQSEGATGQTFVNYWMHNGFVQVDSEKMSKSLGNFFTIREVLEKFDAEVVRFFIVR
HHHHHHCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THYRSPLNYSDVHLDDARASLTRLYTALKDATPDAQPLDWSEAHAQRFAAAMNDDFNTAV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
AVAVLFELATEVNRTREPALARQLRLLAGLLGLLGREPREFLQHAAGAARTGALEPHEIE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCHHHH
ARIAARVAAKQAKNYAEADRIRAELLEAGIALEDKPGGSTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MESLRIYNTLARDKQDFVPRQPGEVRMYVCGITVYDYCHIGHARMVVVFDIVQRWLRARG
CCCHHHHHHHHCCHHHCCCCCCCCEEEEEECEEHHHHHHCCCHHHHHHHHHHHHHHHHCC
YRVTYVRNITDIDDKIIRRAVENGETIQSLTRRFTDAMNADFDALGVERPDLEPRATEFI
CEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHH
PQMLGMIEKLEANGYAYQAKDGDVNYSVRKFANYGRLSGKSLEDLRAGERVAANDAKEDP
HHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKRAKPQEPAGASWESKYGAGRPGWHIECSAMGCTLLGAHFDIHGGGQDLQFPHH
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECEEEECCCCCCCCCCCC
ENEIAQSEGATGQTFVNYWMHNGFVQVDSEKMSKSLGNFFTIREVLEKFDAEVVRFFIVR
HHHHHHCCCCCHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
THYRSPLNYSDVHLDDARASLTRLYTALKDATPDAQPLDWSEAHAQRFAAAMNDDFNTAV
HHHCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
AVAVLFELATEVNRTREPALARQLRLLAGLLGLLGREPREFLQHAAGAARTGALEPHEIE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCHHHH
ARIAARVAAKQAKNYAEADRIRAELLEAGIALEDKPGGSTEWRRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA