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The map label for this gene is citH [H]

Identifier: 126452034

GI number: 126452034

Start: 3287451

End: 3288065

Strand: Reverse

Name: citH [H]

Synonym: BURPS1106A_3366

Alternate gene names: 126452034

Gene position: 3288065-3287451 (Counterclockwise)

Preceding gene: 126453183

Following gene: 126452909

Centisome position: 82.44

GC content: 68.29

Gene sequence:

>615_bases
GTGGCGCATGCCTATAATCGTGCGCGTTCGTCTTCGTCCGCCTTCGCCGTTCGAGGCGGCGCGGCGCTCGGCGCGGTCGT
GCTCGGCACCGTCGCGACTTACCTCGTGCTGTTCATGCCGACCTACGGCGTGAAGGAGTTGAAGCTCGCGCCGTCCGCGG
CGTTCGCCGCGATTCTCGTCGTCGGCGTGATCCAGATGGGTTTCGCGCCGGTGGTCGGGCACTGGTCCGATCGCCACGGC
CGCGTGCGGACGATGTGCGTGCCCGCGCTCGCGATCCTCGTGCTGATCTACCCGGCGTTCGCGTGGCTCGCCGCGCATCC
GACGTTCGGCGCGCTGATCGCCGTGCAGATCGTGTTCGCGTTCCTGATGACCGGCTATTTCGCCGCGCTGCCGGGCCTGC
TTTCGGAGATCTTTCCGGTTGCGACGCGCACGACCGGCATGTCGCTCGCGTATAACGTCGCGGTGACGGTCTTCGGCGGA
TTCGGCCCGTTCATCATCGCGTGGCTGATCCGTGCGACGGGCACGAAAGCCGCGCCCAGCTTCTATCTGATCTTCGCCGC
GCTCGCGAGCCTCGCGGCGCTCGTCGCGCTGCGGCGGCGCTTCGGGTTGCGCTGA

Upstream 100 bases:

>100_bases
CGAGGCCGCCGCGCGCCGCGTGCGATGCGCGGCCGCCGCGTCGCGCCGACGAACCGCCGCGTTCCATATCGGGCGCGGCG
GTTTTCTTTTTTTGGCGTGC

Downstream 100 bases:

>100_bases
CGCGCGGCGTTCGGCGCGCCCCGCATCCGGCGACCCAAGCCTCGTCGGCTCAAACGTCGCCGACTTGGGCCTCTGCGCCA
CGGCCGGCGGAGCCGGAACG

Product: hypothetical protein

Products: betaine [Cytoplasm]; Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: Citrate carrier protein; Citrate transporter [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MAHAYNRARSSSSAFAVRGGAALGAVVLGTVATYLVLFMPTYGVKELKLAPSAAFAAILVVGVIQMGFAPVVGHWSDRHG
RVRTMCVPALAILVLIYPAFAWLAAHPTFGALIAVQIVFAFLMTGYFAALPGLLSEIFPVATRTTGMSLAYNVAVTVFGG
FGPFIIAWLIRATGTKAAPSFYLIFAALASLAALVALRRRFGLR

Sequences:

>Translated_204_residues
MAHAYNRARSSSSAFAVRGGAALGAVVLGTVATYLVLFMPTYGVKELKLAPSAAFAAILVVGVIQMGFAPVVGHWSDRHG
RVRTMCVPALAILVLIYPAFAWLAAHPTFGALIAVQIVFAFLMTGYFAALPGLLSEIFPVATRTTGMSLAYNVAVTVFGG
FGPFIIAWLIRATGTKAAPSFYLIFAALASLAALVALRRRFGLR
>Mature_203_residues
AHAYNRARSSSSAFAVRGGAALGAVVLGTVATYLVLFMPTYGVKELKLAPSAAFAAILVVGVIQMGFAPVVGHWSDRHGR
VRTMCVPALAILVLIYPAFAWLAAHPTFGALIAVQIVFAFLMTGYFAALPGLLSEIFPVATRTTGMSLAYNVAVTVFGGF
GPFIIAWLIRATGTKAAPSFYLIFAALASLAALVALRRRFGLR

Specific function: Uptake of citrate across the boundary membrane with the concomitant transport of protons into the cell (symport system) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790550, Length=179, Percent_Identity=25.6983240223464, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 21526; Mature: 21395

Theoretical pI: Translated: 11.42; Mature: 11.42

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHAYNRARSSSSAFAVRGGAALGAVVLGTVATYLVLFMPTYGVKELKLAPSAAFAAILV
CCCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHH
VGVIQMGFAPVVGHWSDRHGRVRTMCVPALAILVLIYPAFAWLAAHPTFGALIAVQIVFA
HHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FLMTGYFAALPGLLSEIFPVATRTTGMSLAYNVAVTVFGGFGPFIIAWLIRATGTKAAPS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHCCCCCCHH
FYLIFAALASLAALVALRRRFGLR
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHAYNRARSSSSAFAVRGGAALGAVVLGTVATYLVLFMPTYGVKELKLAPSAAFAAILV
CCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHH
VGVIQMGFAPVVGHWSDRHGRVRTMCVPALAILVLIYPAFAWLAAHPTFGALIAVQIVFA
HHHHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FLMTGYFAALPGLLSEIFPVATRTTGMSLAYNVAVTVFGGFGPFIIAWLIRATGTKAAPS
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCHHHHHHHHHHHHCCCCCCHH
FYLIFAALASLAALVALRRRFGLR
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: betaine [Periplasm]; Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + betaine [Periplasm] = Proton [Cytoplasm] + betaine [Cytoplasm] Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2186908 [H]