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The map label for this gene is emrY [H]

Identifier: 126452028

GI number: 126452028

Start: 2237065

End: 2238621

Strand: Direct

Name: emrY [H]

Synonym: BURPS1106A_2250

Alternate gene names: 126452028

Gene position: 2237065-2238621 (Clockwise)

Preceding gene: 126455381

Following gene: 126451624

Centisome position: 56.09

GC content: 67.82

Gene sequence:

>1557_bases
ATGAGTGCCGCGCCGGGCCGACCGCCGCTCTGGAGCGCCGCGAACCTGCGCGGCGATTTCTTTCCATGGGTGCTCGCGAT
CGTCACCGGCCTCGATTACTTCGACAACGCCGCGTTCTCGTTCTTCGCGAGCTACATCGCGGGTGGAATCAACGCGTCGC
CGGACGAGCTCGTGTGGGCGTCGAGCGCTTACGCGGTGACGGCCGTGCTCGGCATCCTGCAGCAGCAATGGTGGGTCGAC
CGGCTCGGTCACCGGCGTTACGTCGCCGGCTGCATGCTGATGTTCTCGCTTGGCGCGATGGCCGCGGCGGCGGCCGACAC
GTCGCTGCAGCTCGCGTTCGCGCGCGGCTTTCAGGGCTATTTCATCGGCCCCATGATGGGCGCGTGCCGGATCCTGATCC
AGGTCAGCTTCGCGCCGAAGGATCGCCCGCCCGCGACGCGCGCGTTCCTCATCATGCTGCTGCTCGGCAGCGCGCTCGCG
CCGATCGCGGGCGGCCTGCTCGTCGCGCACTTCACATGGCGCGCGCTGTTCGCCTGCACGGCGCCGGCCGGCATCCTGTT
CGCGGCGCTCGCGTTCGTCGCGCTGCCCGATTCCGGCCACACGCCGCCCGACGAACGCGGCGGCGCGCATTTCTGGCCGT
ACGTGATCTTCGCGCTCGCGCAAGGCGCGCTGCAGATCGTCATGCAGCAGGTGCGCTTCCAGCTCTTCGCCGGCTCGCCG
CTGCTCGTGCTGCTCGCCGCCGGCGGCCTCGCGGCGCTCGCGTGGTTCGGCCATCATCAGTGGCATCATCCGGCGCCGCT
CGTGCGGCTGCACGCGTTTCGCGAGCGCACGTTCCGGGTCGGCCTGCTGCTCTACCTGTTCTATTACTACGAGACGACGG
GCTACAGCTATCTGATCTCCCGCTTCCTCGAAACCGGGCTCGGCTATCCGATCGAGAACGCCGGGCGGCTCGTCGGCACG
ATGTCGCTGATCTCCGCGAGCGCGCTCTTCGTCTACCTGCGCTACGCGAAGCTTCTCACGCACAAGAAATGGATCATCGT
GCCCGGCTTCGCGCTCGCCGCGTTCGCCGCGCTATGGATGACGCGGATGTCGCCCGAGGTCGGCGAAGCGGCGCTCGTCG
CGCCGCTCCTGATGCGCGGGCTGCTGCTCCTGTTCATCGTGCTGCCCGTCGCGAACCTGACGTTTCGCGTGTTCGCGATC
GACGAGTATTCGCACGGCTACCGGCTGAAGAACATCGTCCGGCAACTGACGATTTCGTTTGCGACCGCCTCCGTCATCAT
CGTCGAGCAGCATCGGCTCGCCGTACATCAGACGCGGCTTGTCGAGCAGGCGAACGTCTACAATCCGCTGTTCCGGCAAA
CCCTCGACACGCTCACGCGCGGCTTCGCGGCCGCGGGCCACGCGTTCTCCGACGCGCACGCGCTCGCGCTCGTCACCGTG
AGCCGCACCATCGCGCAACAGGCGTCGTTCCTGGCGTCGCTCGACGGCTTCTACTTCCTCGCGGGCGTCGCGCTCTGCGG
CGGCCTGTTCGCCGCCTGGCAAAAAGAGATCGATTGA

Upstream 100 bases:

>100_bases
TCGACTATGTCGAGCGCCGGCTCGCCGGCGAAAACCCCGACGAGCTGATCGCGCAGCGCCGCGCCGCCGCGCGCGCGCGC
AAGACGGGCGGGACAAGCGC

Downstream 100 bases:

>100_bases
GGTACGTTTAGCGCCTGTCGCTCCACGCCCTTTTCCGCCTCGATGCTCTCCAAACTCAACCAATGGCTCGACGCGCGCCG
CCGCGATCGCGCGTTGCGCT

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MSAAPGRPPLWSAANLRGDFFPWVLAIVTGLDYFDNAAFSFFASYIAGGINASPDELVWASSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSLGAMAAAAADTSLQLAFARGFQGYFIGPMMGACRILIQVSFAPKDRPPATRAFLIMLLLGSALA
PIAGGLLVAHFTWRALFACTAPAGILFAALAFVALPDSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSP
LLVLLAAGGLAALAWFGHHQWHHPAPLVRLHAFRERTFRVGLLLYLFYYYETTGYSYLISRFLETGLGYPIENAGRLVGT
MSLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWMTRMSPEVGEAALVAPLLMRGLLLLFIVLPVANLTFRVFAI
DEYSHGYRLKNIVRQLTISFATASVIIVEQHRLAVHQTRLVEQANVYNPLFRQTLDTLTRGFAAAGHAFSDAHALALVTV
SRTIAQQASFLASLDGFYFLAGVALCGGLFAAWQKEID

Sequences:

>Translated_518_residues
MSAAPGRPPLWSAANLRGDFFPWVLAIVTGLDYFDNAAFSFFASYIAGGINASPDELVWASSAYAVTAVLGILQQQWWVD
RLGHRRYVAGCMLMFSLGAMAAAAADTSLQLAFARGFQGYFIGPMMGACRILIQVSFAPKDRPPATRAFLIMLLLGSALA
PIAGGLLVAHFTWRALFACTAPAGILFAALAFVALPDSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSP
LLVLLAAGGLAALAWFGHHQWHHPAPLVRLHAFRERTFRVGLLLYLFYYYETTGYSYLISRFLETGLGYPIENAGRLVGT
MSLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWMTRMSPEVGEAALVAPLLMRGLLLLFIVLPVANLTFRVFAI
DEYSHGYRLKNIVRQLTISFATASVIIVEQHRLAVHQTRLVEQANVYNPLFRQTLDTLTRGFAAAGHAFSDAHALALVTV
SRTIAQQASFLASLDGFYFLAGVALCGGLFAAWQKEID
>Mature_517_residues
SAAPGRPPLWSAANLRGDFFPWVLAIVTGLDYFDNAAFSFFASYIAGGINASPDELVWASSAYAVTAVLGILQQQWWVDR
LGHRRYVAGCMLMFSLGAMAAAAADTSLQLAFARGFQGYFIGPMMGACRILIQVSFAPKDRPPATRAFLIMLLLGSALAP
IAGGLLVAHFTWRALFACTAPAGILFAALAFVALPDSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSPL
LVLLAAGGLAALAWFGHHQWHHPAPLVRLHAFRERTFRVGLLLYLFYYYETTGYSYLISRFLETGLGYPIENAGRLVGTM
SLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWMTRMSPEVGEAALVAPLLMRGLLLLFIVLPVANLTFRVFAID
EYSHGYRLKNIVRQLTISFATASVIIVEQHRLAVHQTRLVEQANVYNPLFRQTLDTLTRGFAAAGHAFSDAHALALVTVS
RTIAQQASFLASLDGFYFLAGVALCGGLFAAWQKEID

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=472, Percent_Identity=20.3389830508475, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790195, Length=435, Percent_Identity=24.5977011494253, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789042, Length=430, Percent_Identity=20.2325581395349, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 56592; Mature: 56461

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPGRPPLWSAANLRGDFFPWVLAIVTGLDYFDNAAFSFFASYIAGGINASPDELVWA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSLGAMAAAAADTSLQLAFARGFQGY
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCE
FIGPMMGACRILIQVSFAPKDRPPATRAFLIMLLLGSALAPIAGGLLVAHFTWRALFACT
EHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGILFAALAFVALPDSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLVLLAAGGLAALAWFGHHQWHHPAPLVRLHAFRERTFRVGLLLYLFYYYETTGYSYLIS
HHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFLETGLGYPIENAGRLVGTMSLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWM
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
TRMSPEVGEAALVAPLLMRGLLLLFIVLPVANLTFRVFAIDEYSHGYRLKNIVRQLTISF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHH
ATASVIIVEQHRLAVHQTRLVEQANVYNPLFRQTLDTLTRGFAAAGHAFSDAHALALVTV
HHHEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SRTIAQQASFLASLDGFYFLAGVALCGGLFAAWQKEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAAPGRPPLWSAANLRGDFFPWVLAIVTGLDYFDNAAFSFFASYIAGGINASPDELVWA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
SSAYAVTAVLGILQQQWWVDRLGHRRYVAGCMLMFSLGAMAAAAADTSLQLAFARGFQGY
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCE
FIGPMMGACRILIQVSFAPKDRPPATRAFLIMLLLGSALAPIAGGLLVAHFTWRALFACT
EHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APAGILFAALAFVALPDSGHTPPDERGGAHFWPYVIFALAQGALQIVMQQVRFQLFAGSP
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LLVLLAAGGLAALAWFGHHQWHHPAPLVRLHAFRERTFRVGLLLYLFYYYETTGYSYLIS
HHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFLETGLGYPIENAGRLVGTMSLISASALFVYLRYAKLLTHKKWIIVPGFALAAFAALWM
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHH
TRMSPEVGEAALVAPLLMRGLLLLFIVLPVANLTFRVFAIDEYSHGYRLKNIVRQLTISF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHH
ATASVIIVEQHRLAVHQTRLVEQANVYNPLFRQTLDTLTRGFAAAGHAFSDAHALALVTV
HHHEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
SRTIAQQASFLASLDGFYFLAGVALCGGLFAAWQKEID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]