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The map label for this gene is shlB [H]

Identifier: 126451960

GI number: 126451960

Start: 1112987

End: 1114693

Strand: Direct

Name: shlB [H]

Synonym: BURPS1106A_1132

Alternate gene names: 126451960

Gene position: 1112987-1114693 (Clockwise)

Preceding gene: 126451625

Following gene: 126452240

Centisome position: 27.91

GC content: 61.98

Gene sequence:

>1707_bases
TTGATAGGATATACACAGCAGGTACCGTCCCCTGCCGACCAAGCCGCAGCCGCGCGCGCCAATGCGGAACAGGACCGGCA
GGCGCAGCAGCAACGAGATGCGCAGCAGCGCGATGCGGCCGTGCGTGCCCCGTCCGTGCGCTCCGAGGTGCCGAAGGTCG
AAGCGTACCCGGCGCTCCCGGCGGAAACACCATGCTTTCGTATCGATCGCTTTACGCTCGACGTACCCAACTCCTTGCCC
GACACGACGAAGGCACAGGGGGCGTCCGCCCTCCCGATGGATCGCTTCGCGTTCGCCCGTGCCTGGCTGAACCACTACGC
CGGCCAATGCGTCGGCAAGCAAGGCGTTGACGTGCTGATCAAAGAGCTCTCTCAAGCGATTCTGGCGCGCGGCTACGTCA
CCACACGCGTGCTCGTCCCCGAGCAAGACCTGTCGGCCGGCACGCTGAAATTCTCGCTGATTCCCGGCGTGATTCGCCAT
GTGCGCTTCGCCGACGAAAAACTGCGCGGCACATGGAAGACCGCGTTCCCGACCGGTGACGGCGAAGTGCTGAACCTGCG
CGACCTCGAACAAGGCCTTGAGCAGATGAAGCGCGTGACGAGCCAGGATGTCTCGATGCAGATTGTTCCCGGCGAGCTGC
CCGGTGAAAGCGATGTCGTGCTCGATGTGAAGCGCAGCAAGCCGTGGACCGTCGTCGCATCGATCGACAATTCTGGCACA
CGCGCTACGGGCAAGCTGCAAGGCAACCTGTCGGTCGGCGTCGACAATCCGCTTGGCCTGAACGACATGCTCAACGTTGG
CGTCAGCCAAGACCTCGAATTCGGCGACAAGCGCCTCGGCTCGCACGGCTGGAACGGCTTCTATTCGATTCCGTGGGGTT
ACTGGACTGCCACGCTGTCCGCATACACGAACACCTACTATCAGCAGATTGCGGGTGTGAACCAGACATTCATCGCGAGC
GGCAACTCGAAGACAGTCGATCTCAAACTGGCTCGGGTGCTGGCGCGCAGCCAGAACGACGTGCTCGGAGGGTATTTCCG
GCTGTCCCGCCGTTTCGGCGAGAGCTTTATCGAGGACACTGAGATTTCGCAACAGCGTCGTAACAACACGATCATCGAAC
TCGGTTTGACCGACCGGCACTACTTCGACGGCGCGCAATTCGACGGCTCGCTCGCGTATCGCCAAGGTGTCGGCGGATTC
GGCGCGCAGGACGACACACTGGCGGCGAGCGGCTCGACCTATCGCTTCAAGATGGCCGTGCTCGACGCGAACCTCTCGGT
GCCGTTTGCAATCGGCGAACAACCGTTCCGCTACGTTGGAACGTTCCACGGCCAGTACACCGGAAACACGCTCTACTACC
TCGATGACCTGACGATCGGCAGCCGATATACCGTGCGCGGCTTCGACGGAGAAACGATGCTGGCGGCGTCGCGCGGGTTC
TACTGGCGTAACGAGTTGCAAATGCAGATTGGCCAGACGAGGCAAGCGGTGTATGCAGGGCTGGATTACGGGCGCGTGTG
GGGGCCTCAGCCGATTGCGCTCGTCGGTACGCAGTTGGCCGGCGCCGTCATCGGTATGAAGGGAAGCATCGGGACGCGCT
TCGGTGCCTACGCGTATGACCTGTTTGCAGGCACGCCTGTCTATAAGCCGTCCGGCTTTCCAACTGCGCGTGTCACCGTC
GGATTCCAGCTGACTTCGCAGTTTTGA

Upstream 100 bases:

>100_bases
CGGTCACCTTGCACCCAAGCCTTAAAACAACTTCAACACACGCATCCGAATGAGAATTCGTTCGTCCGCCGTCCTACTGT
CGATTGCCTCCCTTGTGCCA

Downstream 100 bases:

>100_bases
GAGAAGAGTCTCTTGTCGTGGAAGACAGCCACGTGGATGAAATGAACGTATCGAACGACATGCAACCGGTCCGGCTTCCG
CCACGTCGCCCGTGGTTGAA

Product: hemolysin activation/secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MIGYTQQVPSPADQAAAARANAEQDRQAQQQRDAQQRDAAVRAPSVRSEVPKVEAYPALPAETPCFRIDRFTLDVPNSLP
DTTKAQGASALPMDRFAFARAWLNHYAGQCVGKQGVDVLIKELSQAILARGYVTTRVLVPEQDLSAGTLKFSLIPGVIRH
VRFADEKLRGTWKTAFPTGDGEVLNLRDLEQGLEQMKRVTSQDVSMQIVPGELPGESDVVLDVKRSKPWTVVASIDNSGT
RATGKLQGNLSVGVDNPLGLNDMLNVGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIAGVNQTFIAS
GNSKTVDLKLARVLARSQNDVLGGYFRLSRRFGESFIEDTEISQQRRNNTIIELGLTDRHYFDGAQFDGSLAYRQGVGGF
GAQDDTLAASGSTYRFKMAVLDANLSVPFAIGEQPFRYVGTFHGQYTGNTLYYLDDLTIGSRYTVRGFDGETMLAASRGF
YWRNELQMQIGQTRQAVYAGLDYGRVWGPQPIALVGTQLAGAVIGMKGSIGTRFGAYAYDLFAGTPVYKPSGFPTARVTV
GFQLTSQF

Sequences:

>Translated_568_residues
MIGYTQQVPSPADQAAAARANAEQDRQAQQQRDAQQRDAAVRAPSVRSEVPKVEAYPALPAETPCFRIDRFTLDVPNSLP
DTTKAQGASALPMDRFAFARAWLNHYAGQCVGKQGVDVLIKELSQAILARGYVTTRVLVPEQDLSAGTLKFSLIPGVIRH
VRFADEKLRGTWKTAFPTGDGEVLNLRDLEQGLEQMKRVTSQDVSMQIVPGELPGESDVVLDVKRSKPWTVVASIDNSGT
RATGKLQGNLSVGVDNPLGLNDMLNVGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIAGVNQTFIAS
GNSKTVDLKLARVLARSQNDVLGGYFRLSRRFGESFIEDTEISQQRRNNTIIELGLTDRHYFDGAQFDGSLAYRQGVGGF
GAQDDTLAASGSTYRFKMAVLDANLSVPFAIGEQPFRYVGTFHGQYTGNTLYYLDDLTIGSRYTVRGFDGETMLAASRGF
YWRNELQMQIGQTRQAVYAGLDYGRVWGPQPIALVGTQLAGAVIGMKGSIGTRFGAYAYDLFAGTPVYKPSGFPTARVTV
GFQLTSQF
>Mature_568_residues
MIGYTQQVPSPADQAAAARANAEQDRQAQQQRDAQQRDAAVRAPSVRSEVPKVEAYPALPAETPCFRIDRFTLDVPNSLP
DTTKAQGASALPMDRFAFARAWLNHYAGQCVGKQGVDVLIKELSQAILARGYVTTRVLVPEQDLSAGTLKFSLIPGVIRH
VRFADEKLRGTWKTAFPTGDGEVLNLRDLEQGLEQMKRVTSQDVSMQIVPGELPGESDVVLDVKRSKPWTVVASIDNSGT
RATGKLQGNLSVGVDNPLGLNDMLNVGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLSAYTNTYYQQIAGVNQTFIAS
GNSKTVDLKLARVLARSQNDVLGGYFRLSRRFGESFIEDTEISQQRRNNTIIELGLTDRHYFDGAQFDGSLAYRQGVGGF
GAQDDTLAASGSTYRFKMAVLDANLSVPFAIGEQPFRYVGTFHGQYTGNTLYYLDDLTIGSRYTVRGFDGETMLAASRGF
YWRNELQMQIGQTRQAVYAGLDYGRVWGPQPIALVGTQLAGAVIGMKGSIGTRFGAYAYDLFAGTPVYKPSGFPTARVTV
GFQLTSQF

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 62252; Mature: 62252

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGYTQQVPSPADQAAAARANAEQDRQAQQQRDAQQRDAAVRAPSVRSEVPKVEAYPALP
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCC
AETPCFRIDRFTLDVPNSLPDTTKAQGASALPMDRFAFARAWLNHYAGQCVGKQGVDVLI
CCCCCEEEEEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KELSQAILARGYVTTRVLVPEQDLSAGTLKFSLIPGVIRHVRFADEKLRGTWKTAFPTGD
HHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCC
GEVLNLRDLEQGLEQMKRVTSQDVSMQIVPGELPGESDVVLDVKRSKPWTVVASIDNSGT
CCEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCC
RATGKLQGNLSVGVDNPLGLNDMLNVGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLS
EEEEEEEEEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHH
AYTNTYYQQIAGVNQTFIASGNSKTVDLKLARVLARSQNDVLGGYFRLSRRFGESFIEDT
HHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EISQQRRNNTIIELGLTDRHYFDGAQFDGSLAYRQGVGGFGAQDDTLAASGSTYRFKMAV
HHHHHHCCCCEEEEECCCCEECCCCCCCCCCHHHCCCCCCCCCCCCEEECCCCEEEEEEE
LDANLSVPFAIGEQPFRYVGTFHGQYTGNTLYYLDDLTIGSRYTVRGFDGETMLAASRGF
EECCCCCCEEECCCCCEEEEEECCEECCCEEEEEECEEECCEEEEECCCCCEEEEECCCC
YWRNELQMQIGQTRQAVYAGLDYGRVWGPQPIALVGTQLAGAVIGMKGSIGTRFGAYAYD
EEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHEEEECCCCCCCCCCCEEEH
LFAGTPVYKPSGFPTARVTVGFQLTSQF
HHCCCCCCCCCCCCEEEEEEEEEEECCC
>Mature Secondary Structure
MIGYTQQVPSPADQAAAARANAEQDRQAQQQRDAQQRDAAVRAPSVRSEVPKVEAYPALP
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCC
AETPCFRIDRFTLDVPNSLPDTTKAQGASALPMDRFAFARAWLNHYAGQCVGKQGVDVLI
CCCCCEEEEEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KELSQAILARGYVTTRVLVPEQDLSAGTLKFSLIPGVIRHVRFADEKLRGTWKTAFPTGD
HHHHHHHHHCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCC
GEVLNLRDLEQGLEQMKRVTSQDVSMQIVPGELPGESDVVLDVKRSKPWTVVASIDNSGT
CCEEEHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEEECCCCC
RATGKLQGNLSVGVDNPLGLNDMLNVGVSQDLEFGDKRLGSHGWNGFYSIPWGYWTATLS
EEEEEEEEEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHCCCCCCCEEECCCHHHHHHHH
AYTNTYYQQIAGVNQTFIASGNSKTVDLKLARVLARSQNDVLGGYFRLSRRFGESFIEDT
HHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EISQQRRNNTIIELGLTDRHYFDGAQFDGSLAYRQGVGGFGAQDDTLAASGSTYRFKMAV
HHHHHHCCCCEEEEECCCCEECCCCCCCCCCHHHCCCCCCCCCCCCEEECCCCEEEEEEE
LDANLSVPFAIGEQPFRYVGTFHGQYTGNTLYYLDDLTIGSRYTVRGFDGETMLAASRGF
EECCCCCCEEECCCCCEEEEEECCEECCCEEEEEECEEECCEEEEECCCCCEEEEECCCC
YWRNELQMQIGQTRQAVYAGLDYGRVWGPQPIALVGTQLAGAVIGMKGSIGTRFGAYAYD
EEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHEEEECCCCCCCCCCCEEEH
LFAGTPVYKPSGFPTARVTVGFQLTSQF
HHCCCCCCCCCCCCEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]