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The map label for this gene is ortho [H]

Identifier: 126451904

GI number: 126451904

Start: 2256316

End: 2257554

Strand: Reverse

Name: ortho [H]

Synonym: BURPS1106A_2271

Alternate gene names: 126451904

Gene position: 2257554-2256316 (Counterclockwise)

Preceding gene: 126455051

Following gene: 126454983

Centisome position: 56.6

GC content: 64.81

Gene sequence:

>1239_bases
GTGAAACCGATTCAGAAGTCGAACAAGCTGCTCAATGTCTGCTACGACATCCGCGGCCCCGTCCTCGAGCACGCGAAGCG
CCTCGAGGACGAGGGGCATCGCATCATCAAGCTGAATATCGGCAACCTGGCGCCGTTCGGCTTCGACGCGCCGGACGAGA
TCATCCAGGACATGATCCGCAACCTGCCGGCGTCCTCCGGCTATTCGGATTCGAAAGGCGTGTTCGCCGCGCGCAAGGCG
ATCATGCACTACACGCAGCAAAAGGGCGTGCACGGCGTCGGGCTCGACGACATCTACATCGGCAACGGCGCGTCCGAGCT
CATCGTGATGGCGACGCAGGCGTTGCTGAACGACGGCGACGAGGTGCTGCTGCCCGCGCCCGACTATCCGCTCTGGACGG
CGGCCGTGAGCCTGTCGGGCGGCACGCCCGTGCACTACGTCTGCGACGAGTCGAACCGCTGGATGCCCGACCCCGACGAC
ATCCGCCGCAAGATCACGCCGAACACGAAGGCGCTCGTCGTGATCAACCCGAACAACCCGACGGGCGCGCTTTATTCCGA
CGCATTGCTCGTCGAGTTGATCGCGATCGCGCGCGAGCACGGGCTCATCATCTTCGCCGACGAGGTCTACGACAAGATCG
TCTACGACGGCAAGTCGCACACCGCGCTCGCGTCGCTCGCCGAGGACGTGATCACCGTCACGTTCAACAGCCTGTCGAAG
AGCTACCGGTCGTGCGGCTATCGCGCGGGCTGGATGTCGGTCGCGGGGCTCACGGCCGAGAACCGCCGCCGCGCGCACGA
TTACCTGGAGGGGCTCGGCATCCTGTCGTCGATGCGCCTTTGCGCGAACGTGCCCGGCCAGTACGCGATCCAGACCGCGC
TCGGCGGCTATCAGAGCATCAACGAGCTGATCATGCCGAGCGGGCGTCTGTACAAGCAGCGCGAGCTCGCGTACGACATG
CTGACGTCGATTCCCGGCGTGTCGTGCGTGAAGCCGGAAGCGGCGCTCTACATGTTTCCGCGCCTCGATCCGAAGCTCTA
CCCGATCGAGAACGACCAGCAGTTCATCCTCGAGCTGCTGCTGCGGGAGCGCGTGCTGCTCGTGCAGGGCACGGGCTTCA
ACTGGCCGACGCCGGACCACTTCCGCGTCGTGTTCCTGCCGAACGTCGACGACCTGACCGATTCGATCGAGCGGATCGCA
CGCTTTCTCGACGGCTACCGGAAGCGCAACTCGGTCTGA

Upstream 100 bases:

>100_bases
AGCCGCATGAAGCCATTCCTAGACAGCGCGCTACCGGCCGCTCTCCAGTTTTGATCCCCGCCCCCCAGGCCCGCAGGCAT
TACCCAGGAACGTGTCCGCC

Downstream 100 bases:

>100_bases
CCGGGGCGCGTTCCCCCTTTTTCATTCAATAGATCACACGCAGCATGGAACCGATCAAAGTAGGCCTGTTGGGCTTCGGC
ACGGTGGGCGGCGGCACCTT

Product: aminotransferase AlaT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MKPIQKSNKLLNVCYDIRGPVLEHAKRLEDEGHRIIKLNIGNLAPFGFDAPDEIIQDMIRNLPASSGYSDSKGVFAARKA
IMHYTQQKGVHGVGLDDIYIGNGASELIVMATQALLNDGDEVLLPAPDYPLWTAAVSLSGGTPVHYVCDESNRWMPDPDD
IRRKITPNTKALVVINPNNPTGALYSDALLVELIAIAREHGLIIFADEVYDKIVYDGKSHTALASLAEDVITVTFNSLSK
SYRSCGYRAGWMSVAGLTAENRRRAHDYLEGLGILSSMRLCANVPGQYAIQTALGGYQSINELIMPSGRLYKQRELAYDM
LTSIPGVSCVKPEAALYMFPRLDPKLYPIENDQQFILELLLRERVLLVQGTGFNWPTPDHFRVVFLPNVDDLTDSIERIA
RFLDGYRKRNSV

Sequences:

>Translated_412_residues
MKPIQKSNKLLNVCYDIRGPVLEHAKRLEDEGHRIIKLNIGNLAPFGFDAPDEIIQDMIRNLPASSGYSDSKGVFAARKA
IMHYTQQKGVHGVGLDDIYIGNGASELIVMATQALLNDGDEVLLPAPDYPLWTAAVSLSGGTPVHYVCDESNRWMPDPDD
IRRKITPNTKALVVINPNNPTGALYSDALLVELIAIAREHGLIIFADEVYDKIVYDGKSHTALASLAEDVITVTFNSLSK
SYRSCGYRAGWMSVAGLTAENRRRAHDYLEGLGILSSMRLCANVPGQYAIQTALGGYQSINELIMPSGRLYKQRELAYDM
LTSIPGVSCVKPEAALYMFPRLDPKLYPIENDQQFILELLLRERVLLVQGTGFNWPTPDHFRVVFLPNVDDLTDSIERIA
RFLDGYRKRNSV
>Mature_412_residues
MKPIQKSNKLLNVCYDIRGPVLEHAKRLEDEGHRIIKLNIGNLAPFGFDAPDEIIQDMIRNLPASSGYSDSKGVFAARKA
IMHYTQQKGVHGVGLDDIYIGNGASELIVMATQALLNDGDEVLLPAPDYPLWTAAVSLSGGTPVHYVCDESNRWMPDPDD
IRRKITPNTKALVVINPNNPTGALYSDALLVELIAIAREHGLIIFADEVYDKIVYDGKSHTALASLAEDVITVTFNSLSK
SYRSCGYRAGWMSVAGLTAENRRRAHDYLEGLGILSSMRLCANVPGQYAIQTALGGYQSINELIMPSGRLYKQRELAYDM
LTSIPGVSCVKPEAALYMFPRLDPKLYPIENDQQFILELLLRERVLLVQGTGFNWPTPDHFRVVFLPNVDDLTDSIERIA
RFLDGYRKRNSV

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=461, Percent_Identity=29.0672451193059, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI215599424, Length=394, Percent_Identity=30.2030456852792, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4885351, Length=451, Percent_Identity=26.8292682926829, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4507369, Length=393, Percent_Identity=25.9541984732824, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI95147551, Length=183, Percent_Identity=30.0546448087432, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI169881279, Length=183, Percent_Identity=30.0546448087432, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI56713254, Length=165, Percent_Identity=29.0909090909091, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI56713256, Length=165, Percent_Identity=29.0909090909091, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI169881281, Length=156, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI187936925, Length=374, Percent_Identity=24.331550802139, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI14211921, Length=374, Percent_Identity=24.331550802139, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1788627, Length=408, Percent_Identity=64.4607843137255, Blast_Score=570, Evalue=1e-164,
Organism=Escherichia coli, GI1788722, Length=402, Percent_Identity=25.1243781094527, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786816, Length=265, Percent_Identity=24.9056603773585, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=402, Percent_Identity=27.8606965174129, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71981209, Length=463, Percent_Identity=25.9179265658747, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71981215, Length=307, Percent_Identity=27.6872964169381, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=175, Percent_Identity=33.1428571428571, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=175, Percent_Identity=33.1428571428571, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=175, Percent_Identity=31.4285714285714, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320317, Length=417, Percent_Identity=28.537170263789, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6323118, Length=394, Percent_Identity=26.6497461928934, Blast_Score=136, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6322401, Length=244, Percent_Identity=27.4590163934426, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18859735, Length=417, Percent_Identity=28.2973621103118, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI45551451, Length=472, Percent_Identity=26.9067796610169, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24641770, Length=472, Percent_Identity=26.9067796610169, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24641760, Length=472, Percent_Identity=26.9067796610169, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24641768, Length=472, Percent_Identity=26.9067796610169, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24641766, Length=472, Percent_Identity=26.9067796610169, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24641764, Length=472, Percent_Identity=26.9067796610169, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28573069, Length=264, Percent_Identity=23.1060606060606, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24646114, Length=264, Percent_Identity=23.1060606060606, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573067, Length=264, Percent_Identity=23.1060606060606, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573065, Length=264, Percent_Identity=23.1060606060606, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 45827; Mature: 45827

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIQKSNKLLNVCYDIRGPVLEHAKRLEDEGHRIIKLNIGNLAPFGFDAPDEIIQDMIR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPASSGYSDSKGVFAARKAIMHYTQQKGVHGVGLDDIYIGNGASELIVMATQALLNDGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
EVLLPAPDYPLWTAAVSLSGGTPVHYVCDESNRWMPDPDDIRRKITPNTKALVVINPNNP
EEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEECCCCC
TGALYSDALLVELIAIAREHGLIIFADEVYDKIVYDGKSHTALASLAEDVITVTFNSLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SYRSCGYRAGWMSVAGLTAENRRRAHDYLEGLGILSSMRLCANVPGQYAIQTALGGYQSI
HHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
NELIMPSGRLYKQRELAYDMLTSIPGVSCVKPEAALYMFPRLDPKLYPIENDQQFILELL
HHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCHHEEEECCCCCEEECCCCCHHHHHHHH
LRERVLLVQGTGFNWPTPDHFRVVFLPNVDDLTDSIERIARFLDGYRKRNSV
HHCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKPIQKSNKLLNVCYDIRGPVLEHAKRLEDEGHRIIKLNIGNLAPFGFDAPDEIIQDMIR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPASSGYSDSKGVFAARKAIMHYTQQKGVHGVGLDDIYIGNGASELIVMATQALLNDGD
HCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
EVLLPAPDYPLWTAAVSLSGGTPVHYVCDESNRWMPDPDDIRRKITPNTKALVVINPNNP
EEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEECCCCC
TGALYSDALLVELIAIAREHGLIIFADEVYDKIVYDGKSHTALASLAEDVITVTFNSLSK
CCHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SYRSCGYRAGWMSVAGLTAENRRRAHDYLEGLGILSSMRLCANVPGQYAIQTALGGYQSI
HHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
NELIMPSGRLYKQRELAYDMLTSIPGVSCVKPEAALYMFPRLDPKLYPIENDQQFILELL
HHHHCCCCCHHHHHHHHHHHHHHCCCCCEECCCHHEEEECCCCCEEECCCCCHHHHHHHH
LRERVLLVQGTGFNWPTPDHFRVVFLPNVDDLTDSIERIARFLDGYRKRNSV
HHCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]