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The map label for this gene is gcvT [H]

Identifier: 126451834

GI number: 126451834

Start: 3898169

End: 3899287

Strand: Direct

Name: gcvT [H]

Synonym: BURPS1106A_3997

Alternate gene names: 126451834

Gene position: 3898169-3899287 (Clockwise)

Preceding gene: 126453262

Following gene: 126455193

Centisome position: 97.74

GC content: 68.54

Gene sequence:

>1119_bases
ATGACCGTTCTCAAAACCACCCCGCTTCATGCCGCGCATCGCGCCCTCAACGCCCGCATGGTCGATTTCGGCGGCTGGGA
CATGCCCGTCAACTACGGCTCGCAGATCGAAGAGCACCAGGCGGTGCGCACCGATGCCGGCATGTTCGACGTGTCGCACA
TGTGCGTCGTCGATTTCACGGGCCCGCGCGTGCGCGCGTTCTTCGAACACGCGATCGCGAACAACGTCGCGAAGCTGCAA
ACGCCCGGCAAGGCGCTCTACTCGTGCCTGCTGAACCCGCAAGGCGGCGTGATCGACGATCTGATCGTCTACTACTTCAC
CGAGGAATTCTTCCGCGTCGTCGTCAACGCCGGCACCGCGGAGAAGGACATCGCGTGGTTCAACCAGCTCAACGAGCAAG
GCGGCTTCGGCCTCACGATCGCGCCGCGTCGCGACTTCGCGATCGTCGCCGCCCAAGGCCCGAACGCGCGCGCGAAGGTG
TGGGACACCGTCCCCTGCGCGCGCGCAGCGACGAGCGAGCTCAAGCCGTTCAACGCCGCGCAGGTCGCGGGCACGCCGTT
CGGCGATCTCACCGTCGCGCGCACCGGCTACACCGGCGAGGACGGCTTCGAGATCATCGTCCCGGCGACGCACGTGGAAG
CGCTGTGGAACGCGCTCGCCGAGCGCGGCGTGCGCCCGTGCGGGCTCGGCGCGCGCGACACGCTGCGGCTCGAGGCCGGC
ATGAACCTGTACGGCCAGGACATGGACGAAAGCGTTTCCCCGCTCGACGCGGGCCTCGCGTGGACGGTCGACCTGTCCGC
GCCGCGCGCGTTCGTCGGCCGCGACGCGCTCGAAGCGCACGGCTCGCGCGCGGCATTCGTCGGCCTGATCCTGCAGAAGG
AGAACGGCCGCGCGGGCGGCGTGCTGCGCGCGCACCAGAAGGTCGCCACGCCGCACGGCGAAGGCGAGATCACGAGCGGC
ACGTTCTCGCCGTCGATGCAGGAATCGATCGCCTTTGCGCGCGTGCCGAAGGACGTCGCGATCGGCGACACGGTGCACGT
GCAGATCCGCGACAAGCAACTTCCCGCGCGCGTGGTAAAACTGCCGTTCGTGCGCAACGGCAAGGTCCTCGCTGCGTAA

Upstream 100 bases:

>100_bases
TGCACGCATCGCAGGCGGCTTCATGCGCCGGCGGTTCGCCGAGTTGCCGTTTTGTTTTCGCGCCCGGGCTCAAGGCCCGG
CCGCCTTGCCTGGGACCCCG

Downstream 100 bases:

>100_bases
CGGGCCGGGCGGCGCGCCGCCCGGCGATACCGTACCCGGCGCGCCGATTGCGCGCCAGAAAGAATCACACCCTTTTCCAT
TCAGGAGCATTCGATGAGCA

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHAIANNVAKLQ
TPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTAEKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKV
WDTVPCARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAG
MNLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGGVLRAHQKVATPHGEGEITSG
TFSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVKLPFVRNGKVLAA

Sequences:

>Translated_372_residues
MTVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHAIANNVAKLQ
TPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTAEKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKV
WDTVPCARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAG
MNLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGGVLRAHQKVATPHGEGEITSG
TFSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVKLPFVRNGKVLAA
>Mature_371_residues
TVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFTGPRVRAFFEHAIANNVAKLQT
PGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTAEKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKVW
DTVPCARAATSELKPFNAAQVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAGM
NLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGGVLRAHQKVATPHGEGEITSGT
FSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVKLPFVRNGKVLAA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=382, Percent_Identity=36.3874345549738, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI257796258, Length=353, Percent_Identity=36.2606232294618, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI257796256, Length=317, Percent_Identity=35.9621451104101, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI257796254, Length=377, Percent_Identity=31.8302387267904, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI24797151, Length=340, Percent_Identity=28.2352941176471, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI197927446, Length=347, Percent_Identity=24.4956772334294, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI21361378, Length=347, Percent_Identity=24.4956772334294, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789272, Length=378, Percent_Identity=54.2328042328042, Blast_Score=376, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17560118, Length=381, Percent_Identity=34.3832020997375, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71994052, Length=348, Percent_Identity=22.9885057471264, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71994045, Length=348, Percent_Identity=22.9885057471264, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320222, Length=388, Percent_Identity=34.7938144329897, Blast_Score=185, Evalue=1e-47,
Organism=Drosophila melanogaster, GI20129441, Length=380, Percent_Identity=34.2105263157895, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI20130091, Length=306, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571104, Length=276, Percent_Identity=23.9130434782609, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 40093; Mature: 39962

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFT
CCEEECCCHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEECCCEEEEECC
GPRVRAFFEHAIANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTA
CCHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
EKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKVWDTVPCARAATSELKPFNAA
HHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEECCCCCHHHHHHHCCCCCCH
QVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAG
HCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
MNLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGG
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHHHHCCCCEEEEEEEEECCCCCCCC
VLRAHQKVATPHGEGEITSGTFSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVK
EEEHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEE
LPFVRNGKVLAA
CCEEECCCEEEC
>Mature Secondary Structure 
TVLKTTPLHAAHRALNARMVDFGGWDMPVNYGSQIEEHQAVRTDAGMFDVSHMCVVDFT
CEEECCCHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCCEECCCEEEEECC
GPRVRAFFEHAIANNVAKLQTPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTA
CCHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
EKDIAWFNQLNEQGGFGLTIAPRRDFAIVAAQGPNARAKVWDTVPCARAATSELKPFNAA
HHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCCEEECCCCCHHHHHHHCCCCCCH
QVAGTPFGDLTVARTGYTGEDGFEIIVPATHVEALWNALAERGVRPCGLGARDTLRLEAG
HCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
MNLYGQDMDESVSPLDAGLAWTVDLSAPRAFVGRDALEAHGSRAAFVGLILQKENGRAGG
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCHHHHHCCCCEEEEEEEEECCCCCCCC
VLRAHQKVATPHGEGEITSGTFSPSMQESIAFARVPKDVAIGDTVHVQIRDKQLPARVVK
EEEHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCEEEE
LPFVRNGKVLAA
CCEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA