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The map label for this gene is pdxA [H]

Identifier: 126451816

GI number: 126451816

Start: 686238

End: 687287

Strand: Direct

Name: pdxA [H]

Synonym: BURPS1106A_0708

Alternate gene names: 126451816

Gene position: 686238-687287 (Clockwise)

Preceding gene: 226830776

Following gene: 126452897

Centisome position: 17.21

GC content: 72.38

Gene sequence:

>1050_bases
ATGTCCGACCGTCCGCAGCCGCTGCGCATCGCGATCACGACCGGCGAGCCGGCCGGCGTCGGCCCCGAGCTGACGGCCCG
CGCGCTCGCCGACGCGGCGACGCGCTGGCCGGACGCACGCTTCACGGTGCTCGGCGACGCGAGCCTGATCGCCGCGCGCG
CGGCGGCGGTCGGCCTCGATTGGACGCGCATGACGGCGGCGGGGGGCGGTGCGCATGTCGCGGACGCGCACGTCGCCAAC
GCGCATGTCGCCAACGCGCATGTCGCCGTCGCGCATCGCGCGCTTGCCGCGCCCGCCGAGGCGGGCAAGCTGAATCCGGC
GAACGGGCGCTACGTGCTCGATCTGCTCGATGCGGCGATCGACGGCGCGCTCGCCGGCGAATACGACGCGATCGTCACCG
CGCCGCTGCAAAAGAGCACGATCAACGACGCCGGCGTGCCTTTTACCGGCCACACCGAATATCTCGCCGAGCGCACGCGC
ACGCCGCACGTCGTGATGATGCTCGCCGGCACGGGCGAGCGGCCGCTGCGCGTCGCGCTCGCGACGACGCACCTGCCGCT
CAGGGATGTGTCGGCCGCGCTGACGATCGACGGTCTCGCCGATACGCTGTCGATCATCGATCGCGATCTGCGCGGCAGCT
TCGGCCTTGCCGCGCCGCGCATCCTCGTCACGGGGCTCAATCCCCATGCGGGCGAGCACGGCTATCTCGGCCGCGAGGAA
ATCGACGTGATCGAGCCGGCGCTCGAGCGCGCGCGGGCGGCGGGCATCGACGCGCGCGGGCCGTACCCGGCCGATACGCT
GTTCCAGCCGCGTTACCTCGAGCACGCGGATTGCGTGCTCGCGATGTTTCATGATCAGGGGCTGCCGGTCCTCAAGTACG
CGACGTTCGGCGAAGGCATCAACGTCACGCTCGGCCTGCCGATCATCCGCACGTCGGTCGATCACGGCACCGCGCTCGAT
CTCGCCGGCACCGGCCGGGCCGATCCGGGCAGCCTCGTCGCCGCGATCGACACCGCCGTGACGATGGCGCGCCATCGGCG
CGCGGGCTGA

Upstream 100 bases:

>100_bases
CGAGCAGGCGTATTCCGACTGGCTGCGCGAGCTGCGCGACTCGTCGTACGTGCAGATCAAGCTGCCCGTCGCCCAGTAAG
CACGTAGACCTGCGCGTATC

Downstream 100 bases:

>100_bases
GTTTTCGCGTCATCCGTTTCTCTATCTTCCGATGTCGAACAGCAGACAGCACCAAGGGCATTTCGCGCGCAAGCGCTTCG
GGCAGAACTTTCTCGTCGAT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSDRPQPLRIAITTGEPAGVGPELTARALADAATRWPDARFTVLGDASLIAARAAAVGLDWTRMTAAGGGAHVADAHVAN
AHVANAHVAVAHRALAAPAEAGKLNPANGRYVLDLLDAAIDGALAGEYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTR
TPHVVMMLAGTGERPLRVALATTHLPLRDVSAALTIDGLADTLSIIDRDLRGSFGLAAPRILVTGLNPHAGEHGYLGREE
IDVIEPALERARAAGIDARGPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
LAGTGRADPGSLVAAIDTAVTMARHRRAG

Sequences:

>Translated_349_residues
MSDRPQPLRIAITTGEPAGVGPELTARALADAATRWPDARFTVLGDASLIAARAAAVGLDWTRMTAAGGGAHVADAHVAN
AHVANAHVAVAHRALAAPAEAGKLNPANGRYVLDLLDAAIDGALAGEYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTR
TPHVVMMLAGTGERPLRVALATTHLPLRDVSAALTIDGLADTLSIIDRDLRGSFGLAAPRILVTGLNPHAGEHGYLGREE
IDVIEPALERARAAGIDARGPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
LAGTGRADPGSLVAAIDTAVTMARHRRAG
>Mature_348_residues
SDRPQPLRIAITTGEPAGVGPELTARALADAATRWPDARFTVLGDASLIAARAAAVGLDWTRMTAAGGGAHVADAHVANA
HVANAHVAVAHRALAAPAEAGKLNPANGRYVLDLLDAAIDGALAGEYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTRT
PHVVMMLAGTGERPLRVALATTHLPLRDVSAALTIDGLADTLSIIDRDLRGSFGLAAPRILVTGLNPHAGEHGYLGREEI
DVIEPALERARAAGIDARGPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDL
AGTGRADPGSLVAAIDTAVTMARHRRAG

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=335, Percent_Identity=52.8358208955224, Blast_Score=328, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36354; Mature: 36222

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRPQPLRIAITTGEPAGVGPELTARALADAATRWPDARFTVLGDASLIAARAAAVGLD
CCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCC
WTRMTAAGGGAHVADAHVANAHVANAHVAVAHRALAAPAEAGKLNPANGRYVLDLLDAAI
HHHEEECCCCCEEECCHHCCCEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
DGALAGEYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTRTPHVVMMLAGTGERPLRVAL
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEEE
ATTHLPLRDVSAALTIDGLADTLSIIDRDLRGSFGLAAPRILVTGLNPHAGEHGYLGREE
EECCCCHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHH
IDVIEPALERARAAGIDARGPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKYATFGEGI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCHHHEEEEEECCCCCCEEEEEECCCCE
NVTLGLPIIRTSVDHGTALDLAGTGRADPGSLVAAIDTAVTMARHRRAG
EEEECCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDRPQPLRIAITTGEPAGVGPELTARALADAATRWPDARFTVLGDASLIAARAAAVGLD
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCC
WTRMTAAGGGAHVADAHVANAHVANAHVAVAHRALAAPAEAGKLNPANGRYVLDLLDAAI
HHHEEECCCCCEEECCHHCCCEECCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
DGALAGEYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTRTPHVVMMLAGTGERPLRVAL
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEEEE
ATTHLPLRDVSAALTIDGLADTLSIIDRDLRGSFGLAAPRILVTGLNPHAGEHGYLGREE
EECCCCHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCHH
IDVIEPALERARAAGIDARGPYPADTLFQPRYLEHADCVLAMFHDQGLPVLKYATFGEGI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHCHHHEEEEEECCCCCCEEEEEECCCCE
NVTLGLPIIRTSVDHGTALDLAGTGRADPGSLVAAIDTAVTMARHRRAG
EEEECCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA