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The map label for this gene is cysC [H]

Identifier: 126451714

GI number: 126451714

Start: 2543543

End: 2545012

Strand: Reverse

Name: cysC [H]

Synonym: BURPS1106A_2580

Alternate gene names: 126451714

Gene position: 2545012-2543543 (Counterclockwise)

Preceding gene: 126454868

Following gene: 126452346

Centisome position: 63.81

GC content: 73.06

Gene sequence:

>1470_bases
ATGCGGTCCTGCGATGACTTTCTACGGACATCGGAATTGTCCATCGCGGCGGTCAACAGCCTGCGGCGCACCATCGCGCC
GTCGCATCGGGTGCTGGACGCGTGCGGATCGGGCGCCGCCTGCCTGCTGGCGTCGCGCTACGGCGCGAAGCAGGTGGTGG
CGCTCGCGGCCGCAGAGGCGACGCTCGTGGGGGCGCGAGCCGGCGCGAACGGTCCCGGCGAACGGATATCGTTCGTCGAC
GCCGAGCAGGCTGCGGCGCTCGTCGCGCGGCAAGGGCGGTTCGACGTCGTGCTCGGGCTCGCAGGCGGCGGGCGCGACGG
GCTCGATCCGCATTACGGCGCTCGGCTCGACGCGTTCGCACGGCGCTTCGGCACGGCGAACGTTGCCGTCGTGCCCAACG
GTGTGCGCTACGACGCGCAACTCGTCGAATGGCGCGAGGCCGAGCGGCTCGAGGCGGACGTCGCGGCCAGGCAGCGCGCC
CTCGAAGCGCGCTACGACCTCACGCTTGGCCCGGTGCTCGACCAGGTGGCCGCCGGGGCCGCGCCGCGTGGCCGCGTGCG
CGCCGACGCGCTGCGCGCGCTCTGCGCGCGGCTGCCGTTTCTGTCGTGCCGGCCGGGCGATGGCGGTGATGCCGGCACAA
GCGGCACAAGCGGCACGGCGGCGCCCGAGCATGTCGAGTTGACCGCCGCGCACGGCGGCCGTGCCGACGGCGTGCTGTGG
ACGCAGGAGCTGATACACGACGGCATCGTCATCGAACGGATTCAGGGGTGCAGCTGGCTCGACGAACGCGTCGATCTCGA
GGCGGGCGACGCGATCGCGGTGCCCGTCGCCGACATGGCGCGGGCCGCGCCGCTCGACGGCGGCGAAGCGCCGCCGCAGC
TCGCGCCCGCGCCGCGCGCATCCGGCGCGCCCGCGCCGCTCGTCTTCTGGCTGACCGGTATCTCGGGGGCCGGCAAGACG
ACGATCGCGACACGTTTCAAGCAGCGGGCGGACGCCGATGCGTGGCCCACCGTCGTGCTCGACGGCGACACGCTGCGCGG
CGGCCTCAACGCGGATCTCGGCTTCTGCGACGCGGACCGCGCGGAGAACGTGCGCCGCATCGCCGAGGTCGCGGCGCTGA
TGGCCGACACGGGGCTCGTCGTCGTCGTCTCGTGCATTTCGCCCAGGCGGTCGTTTCGCGAAACGGCGCGCGAAATCGTC
GGCGCCGAGCGCTTCGTCGAGGTGTTCGTCGATACGCCGCCCGCGGTCGCGCAGGCGCGCGATCCGAAAGGGCTGTATCG
GCGCGCACGCGCGGGGTTGATCGCGTCGTTCACCGGCATCGATTCGGACTACGAGCCACCGCCGGATCCGCAATTGCGCA
TCGATACGACGACGCACGACGTCGAGGACGCGACGCAGATGCTGCGCCGCTACTACGTCGACGCGCGCCTGTCCGGCGCG
CGTGCGGGCACCGCCGAGTGCGCGGCGTGA

Upstream 100 bases:

>100_bases
CAAATACGACATTCCGAGGGCGCGTGCCTGTATTGCACGCGCATGTCAAAACGATTAAATGACGACGTCCATGAGAGAGC
GTAGACGGGGTATTGCCTTT

Downstream 100 bases:

>100_bases
CGCCGCCACTCCGTTCCTTCCTTCGCCGACGGCCAATAGCGAGACAAACGATGAGCGTTCACGACATGACTCACCCGGGC
GAGCTCGCACCGGTGCGAGC

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: Sulfate adenylyltransferase subunit 1; ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT; Adenylyl-sulfate kinase; APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEATLVGARAGANGPGERISFVD
AEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERLEADVAARQRA
LEARYDLTLGPVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAAHGGRADGVLW
TQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAAPLDGGEAPPQLAPAPRASGAPAPLVFWLTGISGAGKT
TIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRRSFRETAREIV
GAERFVEVFVDTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRRYYVDARLSGA
RAGTAECAA

Sequences:

>Translated_489_residues
MRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEATLVGARAGANGPGERISFVD
AEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERLEADVAARQRA
LEARYDLTLGPVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAAHGGRADGVLW
TQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAAPLDGGEAPPQLAPAPRASGAPAPLVFWLTGISGAGKT
TIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRRSFRETAREIV
GAERFVEVFVDTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRRYYVDARLSGA
RAGTAECAA
>Mature_489_residues
MRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEATLVGARAGANGPGERISFVD
AEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFARRFGTANVAVVPNGVRYDAQLVEWREAERLEADVAARQRA
LEARYDLTLGPVLDQVAAGAAPRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAAHGGRADGVLW
TQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAAPLDGGEAPPQLAPAPRASGAPAPLVFWLTGISGAGKT
TIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADRAENVRRIAEVAALMADTGLVVVVSCISPRRSFRETAREIV
GAERFVEVFVDTPPAVAQARDPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRRYYVDARLSGA
RAGTAECAA

Specific function: APS kinase catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=161, Percent_Identity=53.416149068323, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI34447231, Length=161, Percent_Identity=51.5527950310559, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI62912492, Length=161, Percent_Identity=51.5527950310559, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1789107, Length=167, Percent_Identity=49.7005988023952, Blast_Score=171, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17542422, Length=161, Percent_Identity=45.9627329192547, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322852, Length=172, Percent_Identity=44.1860465116279, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24667032, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667028, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667036, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667040, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI116007838, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24667044, Length=161, Percent_Identity=49.0683229813665, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891
- InterPro:   IPR000795
- InterPro:   IPR011779
- InterPro:   IPR009001
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF01583 APS_kinase; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: =2.7.7.4; =2.7.1.25 [H]

Molecular weight: Translated: 51418; Mature: 51418

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEA
CCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHH
TLVGARAGANGPGERISFVDAEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFA
HEEECCCCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHH
RRFGTANVAVVPNGVRYDAQLVEWREAERLEADVAARQRALEARYDLTLGPVLDQVAAGA
HHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
APRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAAHGGRADGVLW
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHH
TQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAAPLDGGEAPPQLAPAPRA
HHHHHHCCHHHHHHCCCCHHHHHCCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCCCCCC
SGAPAPLVFWLTGISGAGKTTIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADR
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHH
AENVRRIAEVAALMADTGLVVVVSCISPRRSFRETAREIVGAERFVEVFVDTPPAVAQAR
HHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
DPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRRYYVDARLSGA
CCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCC
RAGTAECAA
CCCCHHCCC
>Mature Secondary Structure
MRSCDDFLRTSELSIAAVNSLRRTIAPSHRVLDACGSGAACLLASRYGAKQVVALAAAEA
CCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHH
TLVGARAGANGPGERISFVDAEQAAALVARQGRFDVVLGLAGGGRDGLDPHYGARLDAFA
HEEECCCCCCCCCCCEEEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHH
RRFGTANVAVVPNGVRYDAQLVEWREAERLEADVAARQRALEARYDLTLGPVLDQVAAGA
HHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCC
APRGRVRADALRALCARLPFLSCRPGDGGDAGTSGTSGTAAPEHVELTAAHGGRADGVLW
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHH
TQELIHDGIVIERIQGCSWLDERVDLEAGDAIAVPVADMARAAPLDGGEAPPQLAPAPRA
HHHHHHCCHHHHHHCCCCHHHHHCCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCCCCCC
SGAPAPLVFWLTGISGAGKTTIATRFKQRADADAWPTVVLDGDTLRGGLNADLGFCDADR
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHH
AENVRRIAEVAALMADTGLVVVVSCISPRRSFRETAREIVGAERFVEVFVDTPPAVAQAR
HHHHHHHHHHHHHHHCCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
DPKGLYRRARAGLIASFTGIDSDYEPPPDPQLRIDTTTHDVEDATQMLRRYYVDARLSGA
CCHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCC
RAGTAECAA
CCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]