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The map label for this gene is yjeP [H]

Identifier: 126451675

GI number: 126451675

Start: 2116659

End: 2119088

Strand: Direct

Name: yjeP [H]

Synonym: BURPS1106A_2125

Alternate gene names: 126451675

Gene position: 2116659-2119088 (Clockwise)

Preceding gene: 126454016

Following gene: 126455141

Centisome position: 53.07

GC content: 69.71

Gene sequence:

>2430_bases
ATGATCCGTCTTGCGACATTCGCGCGCCGCGTCGCGCTGATAGGCCTATTGCATCTGCTCTGCGCGGCGTTGCCCGCGGC
GGCGGCCGACCTCGCGTCCGGCGCGAGCGTGCCGCCCGCGCCGGCGATCTCGCGTGACGAGGCGCTCGCCGAACTGAAGC
GCGTGCAGGCCGCGCTCGACCGGATCAAGCAGCAGGCGTCGGCCGCGACCACCTACAAGCAACTGGACGCGCTCGACGAA
TCGACGCAAGCGCTGAGCGCCGACGTCGACAAGCTGACGGCGGCGCTCGTGCCCACGCGCGCGCAGCTTCAGGCGCAGCT
CGACGTGCTCGGGCCGCCGCCCGCGCCGGGCGCGGCGCCCGAAACGCCCGCCGTCGCGCGGCAGCGCGCGGACCTGAACG
CGCGCAAGACGCAGCTCGACGCCGCGCTCAAGCAGGCCGCCGACGAGAAGGAAAGCCTCGCGAACCTGACACAGCAATAC
TCGAAGCTGCGCCGCAGCCTGCTGCGCGACCAGCTCGTGCTGCGCTCGAGCAGCATTCTCGGCCCGCGGTTCTGGGCCCC
GCTCTTTCGTCCGTCGGACGATGATCGGCAGGAACTCGGCGCGTTCAGCGCGCAGATCGGGCAAGTGCTTGCCGCGGCAT
GGGAGCCGGGCCGCCGGCTCGGCACCGCGCTGCTGCTCGCCGCCGCGCTCGCCGTGTGGACGCTCGGCAGGCGGCTCGCC
GAGCGCGCGCTCGCGTGGTTCAGCCTGACGAAGCTGCCGGAGACGCGCGTGCGGCGCAGCGCGCTCGCGACGTCGATCGC
GCTGTCGAGCGTCGTGACGACGGGCATCGCCGTGCAATTCGTCTATCTCGCGCTCACGCGCGACTACGCGCTGTCGAGCG
CGCTGCAGGATTTCGCCGACGAGCTCGCGAAGCTCGCGCTGACTTGCGCGCTGATCGCGGGGCTCGGGCGCGCGCTGCTG
TGCACCCACCATCCGAGCTGGCGGCTGCCCGCGCTTGCCGACGAAGTCGCGCTCGCGATGCGGCCGTTCCCGGCGATCCT
CGCGGCGCTGCTGCTCGTCGCGGGCGCGCTCGAGGAACTGAACCGAACCGCCGACACGAGCCTGCAGGTCACGCTGTTCG
GGCGCGGAATCGTGTCGCTCGTCGTCGTCGTGACGATCGGCGCGTCGCTGCTGCGCGCGAACCGCGCGCGCACCGCGCTC
GCCGCCGCGGGCGAGCCGCCCGAGGCGCGCTCGACGCTCGCGGGGCTGATCCACGCGGGCGTCACGCTGACCGTCGTCGC
GGCGCTCGCCGCGCTCCTCATCGGCTACATCTCGGTCGCGCGCTTTCTCACCTATGAGCTCGTGTGGTTCGAGATCGTGA
TCGGCAGCGTGTACTTGCTGACGCGCCTCACCCGCGACGCATACGCGAGCGCGTTCGCCGCGAACCTGTCGAGCGGCCGG
CTGATCAAGCATCTGTTCGGGCTGAACGACAGCCACCTCGATCAGGCACGCACCGTGCTGACCGGAATCAGCACGAGCGT
GCTGCTGCTCGTCGCCGTCATCGCGCTGCTGACGGGCGGCTTCGGCACGACGCCGAACGATCTGCTCGTGAGCGTGATCT
CGATGTTCGGCGGCGACAAACTGCAACGCCTGAACATCGTGCCCGCCCGCATCCTGAACGCGGCGCTCGCGCTGGCGATC
GGCATCTATCTGCTGCGCTCGGTGCGCCGCTGGCTGGACAACGAGCTGCTGCCGGCGATCGGCCTGGATCAGGGCATGCG
CGCGTCGCTCGTCACGCTGTTCAGCAATCTCGGCTATGTCGCGCTCGTGCTGCTCGCGCTGTCGCTGCTCGGCGTCAAAT
GGGACAACCTCGCGTGGATCGTGAGCGCGCTGTCGGTGGGCATCGGCTTCGGCCTGCAGGAGATCGTGAAGAACTTCGTG
TCCGGGCTGATCCTGCTCACCGAGCGGCCCGTGAAGGTCGGCGACATGATCAGCATCTCGGGCGTCGAAGGCGACATCCG
CCGGATCAACGTGCGCGCGACCGAGATCCAGCTGTCCGACCGCTCGACGGTGATCGTGCCGAACTCGCAATTGATCTCGC
AGAACCTGCGTAACGTGACGATGGGCAACAGCACGCAGGGCGTCGCGACGCTGATGCTCACGTTTCCGCTCAACACCGAT
CCCGAGCAGGTGCGCGATCTGCTGCTCGACGCATACCGCGAGCACGCGTCGGTGCTCGAGAAGCCCGCGCCGTCCGTCAC
CTTCAGCCAGCTGACGCCGGACGGGATCACGCTCAGCGTGACGGGGTACGTCGGCAGCCCGCGGATCGCGGCGGCGACGA
AGAGCGACCTGCTGTTCGAGATTCTCAAGCGACTGCGCGCGGCGGGCATCGCGCTGTCGAATCCGCAGACGCTGATGGTG
CAGAATCTGCCGCCGCCTTCGAGCGAGTGA

Upstream 100 bases:

>100_bases
TGTTTCGGATTGTCGTCGGCGATCCGTGAGCCGAAAAACCGTGGCAATCTACAGTGCAATCCGGTTGTCCATTCGCGCAA
CCGATCTGTAAGGTTTCCCG

Downstream 100 bases:

>100_bases
GCGAGTGAGCGAGCCAATGAGCGCGAGCGCGCGGGATGACCGGGCACGAGCGCGGCATGCCATTTCGCTTGCGGTGCGAA
CCGGTGTACGCGAGCACGCG

Product: small conductance mechanosensitive ion channel (MscS) family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 809; Mature: 809

Protein sequence:

>809_residues
MIRLATFARRVALIGLLHLLCAALPAAAADLASGASVPPAPAISRDEALAELKRVQAALDRIKQQASAATTYKQLDALDE
STQALSADVDKLTAALVPTRAQLQAQLDVLGPPPAPGAAPETPAVARQRADLNARKTQLDAALKQAADEKESLANLTQQY
SKLRRSLLRDQLVLRSSSILGPRFWAPLFRPSDDDRQELGAFSAQIGQVLAAAWEPGRRLGTALLLAAALAVWTLGRRLA
ERALAWFSLTKLPETRVRRSALATSIALSSVVTTGIAVQFVYLALTRDYALSSALQDFADELAKLALTCALIAGLGRALL
CTHHPSWRLPALADEVALAMRPFPAILAALLLVAGALEELNRTADTSLQVTLFGRGIVSLVVVVTIGASLLRANRARTAL
AAAGEPPEARSTLAGLIHAGVTLTVVAALAALLIGYISVARFLTYELVWFEIVIGSVYLLTRLTRDAYASAFAANLSSGR
LIKHLFGLNDSHLDQARTVLTGISTSVLLLVAVIALLTGGFGTTPNDLLVSVISMFGGDKLQRLNIVPARILNAALALAI
GIYLLRSVRRWLDNELLPAIGLDQGMRASLVTLFSNLGYVALVLLALSLLGVKWDNLAWIVSALSVGIGFGLQEIVKNFV
SGLILLTERPVKVGDMISISGVEGDIRRINVRATEIQLSDRSTVIVPNSQLISQNLRNVTMGNSTQGVATLMLTFPLNTD
PEQVRDLLLDAYREHASVLEKPAPSVTFSQLTPDGITLSVTGYVGSPRIAAATKSDLLFEILKRLRAAGIALSNPQTLMV
QNLPPPSSE

Sequences:

>Translated_809_residues
MIRLATFARRVALIGLLHLLCAALPAAAADLASGASVPPAPAISRDEALAELKRVQAALDRIKQQASAATTYKQLDALDE
STQALSADVDKLTAALVPTRAQLQAQLDVLGPPPAPGAAPETPAVARQRADLNARKTQLDAALKQAADEKESLANLTQQY
SKLRRSLLRDQLVLRSSSILGPRFWAPLFRPSDDDRQELGAFSAQIGQVLAAAWEPGRRLGTALLLAAALAVWTLGRRLA
ERALAWFSLTKLPETRVRRSALATSIALSSVVTTGIAVQFVYLALTRDYALSSALQDFADELAKLALTCALIAGLGRALL
CTHHPSWRLPALADEVALAMRPFPAILAALLLVAGALEELNRTADTSLQVTLFGRGIVSLVVVVTIGASLLRANRARTAL
AAAGEPPEARSTLAGLIHAGVTLTVVAALAALLIGYISVARFLTYELVWFEIVIGSVYLLTRLTRDAYASAFAANLSSGR
LIKHLFGLNDSHLDQARTVLTGISTSVLLLVAVIALLTGGFGTTPNDLLVSVISMFGGDKLQRLNIVPARILNAALALAI
GIYLLRSVRRWLDNELLPAIGLDQGMRASLVTLFSNLGYVALVLLALSLLGVKWDNLAWIVSALSVGIGFGLQEIVKNFV
SGLILLTERPVKVGDMISISGVEGDIRRINVRATEIQLSDRSTVIVPNSQLISQNLRNVTMGNSTQGVATLMLTFPLNTD
PEQVRDLLLDAYREHASVLEKPAPSVTFSQLTPDGITLSVTGYVGSPRIAAATKSDLLFEILKRLRAAGIALSNPQTLMV
QNLPPPSSE
>Mature_809_residues
MIRLATFARRVALIGLLHLLCAALPAAAADLASGASVPPAPAISRDEALAELKRVQAALDRIKQQASAATTYKQLDALDE
STQALSADVDKLTAALVPTRAQLQAQLDVLGPPPAPGAAPETPAVARQRADLNARKTQLDAALKQAADEKESLANLTQQY
SKLRRSLLRDQLVLRSSSILGPRFWAPLFRPSDDDRQELGAFSAQIGQVLAAAWEPGRRLGTALLLAAALAVWTLGRRLA
ERALAWFSLTKLPETRVRRSALATSIALSSVVTTGIAVQFVYLALTRDYALSSALQDFADELAKLALTCALIAGLGRALL
CTHHPSWRLPALADEVALAMRPFPAILAALLLVAGALEELNRTADTSLQVTLFGRGIVSLVVVVTIGASLLRANRARTAL
AAAGEPPEARSTLAGLIHAGVTLTVVAALAALLIGYISVARFLTYELVWFEIVIGSVYLLTRLTRDAYASAFAANLSSGR
LIKHLFGLNDSHLDQARTVLTGISTSVLLLVAVIALLTGGFGTTPNDLLVSVISMFGGDKLQRLNIVPARILNAALALAI
GIYLLRSVRRWLDNELLPAIGLDQGMRASLVTLFSNLGYVALVLLALSLLGVKWDNLAWIVSALSVGIGFGLQEIVKNFV
SGLILLTERPVKVGDMISISGVEGDIRRINVRATEIQLSDRSTVIVPNSQLISQNLRNVTMGNSTQGVATLMLTFPLNTD
PEQVRDLLLDAYREHASVLEKPAPSVTFSQLTPDGITLSVTGYVGSPRIAAATKSDLLFEILKRLRAAGIALSNPQTLMV
QNLPPPSSE

Specific function: Unknown

COG id: COG3264

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=365, Percent_Identity=29.8630136986301, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1786670, Length=255, Percent_Identity=34.1176470588235, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1789291, Length=245, Percent_Identity=23.265306122449, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1787591, Length=217, Percent_Identity=25.3456221198157, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 86183; Mature: 86183

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLATFARRVALIGLLHLLCAALPAAAADLASGASVPPAPAISRDEALAELKRVQAALD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RIKQQASAATTYKQLDALDESTQALSADVDKLTAALVPTRAQLQAQLDVLGPPPAPGAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
ETPAVARQRADLNARKTQLDAALKQAADEKESLANLTQQYSKLRRSLLRDQLVLRSSSIL
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GPRFWAPLFRPSDDDRQELGAFSAQIGQVLAAAWEPGRRLGTALLLAAALAVWTLGRRLA
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERALAWFSLTKLPETRVRRSALATSIALSSVVTTGIAVQFVYLALTRDYALSSALQDFAD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAKLALTCALIAGLGRALLCTHHPSWRLPALADEVALAMRPFPAILAALLLVAGALEEL
HHHHHHHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NRTADTSLQVTLFGRGIVSLVVVVTIGASLLRANRARTALAAAGEPPEARSTLAGLIHAG
HHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VTLTVVAALAALLIGYISVARFLTYELVWFEIVIGSVYLLTRLTRDAYASAFAANLSSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LIKHLFGLNDSHLDQARTVLTGISTSVLLLVAVIALLTGGFGTTPNDLLVSVISMFGGDK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCH
LQRLNIVPARILNAALALAIGIYLLRSVRRWLDNELLPAIGLDQGMRASLVTLFSNLGYV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHH
ALVLLALSLLGVKWDNLAWIVSALSVGIGFGLQEIVKNFVSGLILLTERPVKVGDMISIS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCCCCEEEEC
GVEGDIRRINVRATEIQLSDRSTVIVPNSQLISQNLRNVTMGNSTQGVATLMLTFPLNTD
CCCCCCEEEEEEEEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
PEQVRDLLLDAYREHASVLEKPAPSVTFSQLTPDGITLSVTGYVGSPRIAAATKSDLLFE
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
ILKRLRAAGIALSNPQTLMVQNLPPPSSE
HHHHHHHCCCEECCCCEEEEECCCCCCCC
>Mature Secondary Structure
MIRLATFARRVALIGLLHLLCAALPAAAADLASGASVPPAPAISRDEALAELKRVQAALD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RIKQQASAATTYKQLDALDESTQALSADVDKLTAALVPTRAQLQAQLDVLGPPPAPGAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCC
ETPAVARQRADLNARKTQLDAALKQAADEKESLANLTQQYSKLRRSLLRDQLVLRSSSIL
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GPRFWAPLFRPSDDDRQELGAFSAQIGQVLAAAWEPGRRLGTALLLAAALAVWTLGRRLA
CCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERALAWFSLTKLPETRVRRSALATSIALSSVVTTGIAVQFVYLALTRDYALSSALQDFAD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELAKLALTCALIAGLGRALLCTHHPSWRLPALADEVALAMRPFPAILAALLLVAGALEEL
HHHHHHHHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
NRTADTSLQVTLFGRGIVSLVVVVTIGASLLRANRARTALAAAGEPPEARSTLAGLIHAG
HHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
VTLTVVAALAALLIGYISVARFLTYELVWFEIVIGSVYLLTRLTRDAYASAFAANLSSGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LIKHLFGLNDSHLDQARTVLTGISTSVLLLVAVIALLTGGFGTTPNDLLVSVISMFGGDK
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCH
LQRLNIVPARILNAALALAIGIYLLRSVRRWLDNELLPAIGLDQGMRASLVTLFSNLGYV
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHH
ALVLLALSLLGVKWDNLAWIVSALSVGIGFGLQEIVKNFVSGLILLTERPVKVGDMISIS
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEECCCCCCCCEEEEC
GVEGDIRRINVRATEIQLSDRSTVIVPNSQLISQNLRNVTMGNSTQGVATLMLTFPLNTD
CCCCCCEEEEEEEEEEEECCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCC
PEQVRDLLLDAYREHASVLEKPAPSVTFSQLTPDGITLSVTGYVGSPRIAAATKSDLLFE
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
ILKRLRAAGIALSNPQTLMVQNLPPPSSE
HHHHHHHCCCEECCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]