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The map label for this gene is fdhA [H]

Identifier: 126451671

GI number: 126451671

Start: 2505214

End: 2507547

Strand: Reverse

Name: fdhA [H]

Synonym: BURPS1106A_2551

Alternate gene names: 126451671

Gene position: 2507547-2505214 (Counterclockwise)

Preceding gene: 126451722

Following gene: 126452482

Centisome position: 62.87

GC content: 68.25

Gene sequence:

>2334_bases
ATGCGCCGGCAGATGGAGCGTGCGATGGCAGTCGAGAAAACCGCCTGTATTCTGTGTTCGCGCAATTGCGGCCTTGTCGT
CGACGTCACGGACGGCAAGTTCGCGAAGATCCGAGGCGACGACGATCATCCGGTTTCGAAAGGCTATCTGTGTCAGAAGG
CCGCGCGTCTCACGTACTACCAGCATCACGACGATCGCCTCACGCACCCGCTGCGCCGCGAGCCCGACGGCAGCTTCGTG
CGCGTCACATGGGACGAGGCGCTCGACGACATCGCGCAGCGCCTCGTCGCGCTGCGCGAGCGGCATGGCGGCGACGCGTT
CGCGTTCGTCGGCGGGGGCGGGCAGGGCAACCACGTCGGCGGCGCGTACAGCCGGCAGTTGCTCGCCGCGATGCGCAGCC
GCTACGCGTACAACGCGCTCGGCCAGGAGAAGACGGGCGACTTCTGGCTCAACGGGCGGCTGTTCGGCCGTCAGGACTGC
CACACGACCGAGGACATCGAGCATGCGGATTACGTGCTCGTCATCGGCGCGAATCCGTATCAGGCGCACGGGATTCCGAA
TGCGCGCGACACGCTGCGCGATCTGAAGAAGGATCCGGCGCGCACGCTCGTCGTCGTCGATCCGCGCCGCTCGGAGACGG
CGAAGTTCGCCGATCTGCATCTGCAGGTGCGGCCGGGCGCGGACGCGTATCTGATGAGCGCGATGCTCGCGATCATGCTG
CGCGACGGGCTGTTCGACCGCGCGTTCATCGCGCAGCGCTGCACGGGCTTCGAGTTCGTCGAGCGCGTGCTGCGCGACGT
GCCGATCGCCGAATACGCGCGCCGCGCGGACGTGCCGCTCGAGGACATCGAGCGCGTCGCGCACGGCTTCGCGACCGCGC
GCGCGGCATGCCTGCGCATCGATCTCGGCATCCAGCACACGCTGCACACGACGCTCAACGGCTACCTCGAGAAGCTGCTG
TTCCTGCTGACGGGCCACTTCGGCAAGCGCGGCGGCAACAACCTGCATTCGTTCCTGCTGCCCGTCATCGGCCATACCGA
CGAGCGCGCGATCCGTCACGGCAAGCCGCTCAAGCGGACCGCGCATCACCGGATGTTTCCGATCGCGGGCATCTATCCGC
CGAACATCCTGCCCGACGAGATCGAGCGCGCGGGCGAGAAGCGCGTGCGCGCGGCGTTCGTCGACAGCGCGAATCCGGTC
GTCACGTATGCCGATACGAACGCATATGAACGCGCGTTCGGCAAGCTGGAGCTGCTCGTCGTGATCGACGTCGCGATGAC
CGAAACCGCGCGCCTCGCGCATTACGTGCTGCCCGCCGCGTCGCAGTTCGAGAAGTGGGAGGCGACGGGCTTCAACCTCG
AGTTCCCGGCGAACGCGTTTCATCTGCGCCATCCGCTGCTGCCGCCGCTCGGCGAGTCGCTGCCGGAGCCGGAGATCTAT
ACGCGGCTGCTCGAGAAGATGGGCGAGCTGCCGCGCCGCTTTCCGCTTCTGGAGCGCATCGCGCGGTTCGAGCCGCGCGC
GTCGAAGCATCTGGCCTACCTGGGCGCGCTCGGGATCGTGCTCGCGGCGAACAAGAAGTGGCAGCGTCACGCGGCGTCGA
TCGTCTATCGCACGCTCGGCCGCGCGTTGCCGGGCGACGCGGCGGCGAGCGCGCCGCTGCTGCCGCTCGCGATGCTGTAC
GCGCAGCGGCATTACGCGGCCGTGCGCCGCGCCGGATTTCGCGGCAATCGCGCGACGCTCGGCACGGCGCTCTTTCGCGC
GATTCTCGAGCGCCGCTCGGGGACGCTCATCAGCGTGCACGAATTCGACGAGATGTGGCGCTTCATCCGCCATCCGGACG
CTCGCGTGCACCTGCACATCCCGGAGATGATCGACGAGCTGCGCGCGCTCGCGACCGAGACGCCGCCCGGCGCCGACTAT
CCGTTCGTGCTGATGGCGGGCGAGCGGCGCGCGTACAACGCGAACCAGATTTATCGCGATCCGACGTGGCGCAAGGTCGA
TCCGCACGGCTCGCTGCGGATTCATCCGGACGACGCGGCGGCGCTGGGTGTCGCGGACGGCGGCAAGCTCGTGTGCGCGT
CGGCGACGGGCAGCATCGAAGTCGTCGCCGAGCTCGACGATAGCGTGCGGCGCGGGATGGTCACGTTGCCGCACGGCTAC
GGCATGCGCTACAAGGGCGGGCCGCCCGTCGGTCCCGAGCTCAATCGCCTGACCTCGGGCGCGCATTGCGATCCGCTGTC
GCGCACGCCTTATCACAAATATGTGCCCGTGCATTTGCGCGTCGTCGATACGCCGGTTGCCGCGCCCGCGACGCTCGAAG
CCGAATCGGCTTGA

Upstream 100 bases:

>100_bases
GTTTGGAGCGTCTGTTCGATTGACTCCGATCAATGCATCGCATAACGTTCGTTTCCATAACGATCGTTATTTCATATTCA
TTCTTCCCCGATTCCGGCGG

Downstream 100 bases:

>100_bases
TGGCGCGCGCGCTCGTGCGCCTTCGTGCACGCGGCGGCGCAGGCTGACGTGCCGCCGCGTGCACGGCGGGATAGCGCATG
GTCGTTCGCGCGCCGGAACG

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MRRQMERAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHDDRLTHPLRREPDGSFV
RVTWDEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDC
HTTEDIEHADYVLVIGANPYQAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIML
RDGLFDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGIQHTLHTTLNGYLEKLL
FLLTGHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPV
VTYADTNAYERAFGKLELLVVIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIY
TRLLEKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALPGDAAASAPLLPLAMLY
AQRHYAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADY
PFVLMAGERRAYNANQIYRDPTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGY
GMRYKGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA

Sequences:

>Translated_777_residues
MRRQMERAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHDDRLTHPLRREPDGSFV
RVTWDEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDC
HTTEDIEHADYVLVIGANPYQAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIML
RDGLFDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGIQHTLHTTLNGYLEKLL
FLLTGHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPV
VTYADTNAYERAFGKLELLVVIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIY
TRLLEKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALPGDAAASAPLLPLAMLY
AQRHYAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADY
PFVLMAGERRAYNANQIYRDPTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGY
GMRYKGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA
>Mature_777_residues
MRRQMERAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYYQHHDDRLTHPLRREPDGSFV
RVTWDEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVGGAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDC
HTTEDIEHADYVLVIGANPYQAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIML
RDGLFDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRIDLGIQHTLHTTLNGYLEKLL
FLLTGHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRTAHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPV
VTYADTNAYERAFGKLELLVVIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIY
TRLLEKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLGRALPGDAAASAPLLPLAMLY
AQRHYAAVRRAGFRGNRATLGTALFRAILERRSGTLISVHEFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADY
PFVLMAGERRAYNANQIYRDPTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGY
GMRYKGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=471, Percent_Identity=28.0254777070064, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787870, Length=488, Percent_Identity=25.2049180327869, Blast_Score=116, Evalue=6e-27,
Organism=Escherichia coli, GI171474008, Length=374, Percent_Identity=25.668449197861, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI87081797, Length=508, Percent_Identity=23.4251968503937, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788534, Length=260, Percent_Identity=25.7692307692308, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI145693196, Length=470, Percent_Identity=26.3829787234043, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 86575; Mature: 86575

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQMERAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYY
CCHHHHHHHHHHHHEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHE
QHHDDRLTHPLRREPDGSFVRVTWDEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVG
ECCCCHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
GAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDCHTTEDIEHADYVLVIGANPY
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEECCCCCCCCCCCCCCCEEEEECCCCC
QAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIML
CCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
RDGLFDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRI
HCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEE
DLGIQHTLHTTLNGYLEKLLFLLTGHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRT
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHH
AHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPVVTYADTNAYERAFGKLELLV
HHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCHHHHHHCCEEEEE
VIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIY
EEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCCCCCCCHHHH
TRLLEKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLG
HHHHHHHHHCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
RALPGDAAASAPLLPLAMLYAQRHYAAVRRAGFRGNRATLGTALFRAILERRSGTLISVH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEHH
EFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADYPFVLMAGERRAYNANQIYRD
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCC
PTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGY
CCCCEECCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEEEEECHHHHHCCEEECCCCC
GMRYKGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MRRQMERAMAVEKTACILCSRNCGLVVDVTDGKFAKIRGDDDHPVSKGYLCQKAARLTYY
CCHHHHHHHHHHHHEEEEEECCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHE
QHHDDRLTHPLRREPDGSFVRVTWDEALDDIAQRLVALRERHGGDAFAFVGGGGQGNHVG
ECCCCHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
GAYSRQLLAAMRSRYAYNALGQEKTGDFWLNGRLFGRQDCHTTEDIEHADYVLVIGANPY
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEECCCCCCCCCCCCCCCEEEEECCCCC
QAHGIPNARDTLRDLKKDPARTLVVVDPRRSETAKFADLHLQVRPGADAYLMSAMLAIML
CCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHH
RDGLFDRAFIAQRCTGFEFVERVLRDVPIAEYARRADVPLEDIERVAHGFATARAACLRI
HCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEE
DLGIQHTLHTTLNGYLEKLLFLLTGHFGKRGGNNLHSFLLPVIGHTDERAIRHGKPLKRT
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHCCCCHHHH
AHHRMFPIAGIYPPNILPDEIERAGEKRVRAAFVDSANPVVTYADTNAYERAFGKLELLV
HHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEEEECCCHHHHHHCCEEEEE
VIDVAMTETARLAHYVLPAASQFEKWEATGFNLEFPANAFHLRHPLLPPLGESLPEPEIY
EEEHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCHHHHCCCCCCCCCCCCCCHHHH
TRLLEKMGELPRRFPLLERIARFEPRASKHLAYLGALGIVLAANKKWQRHAASIVYRTLG
HHHHHHHHHCHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
RALPGDAAASAPLLPLAMLYAQRHYAAVRRAGFRGNRATLGTALFRAILERRSGTLISVH
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEHH
EFDEMWRFIRHPDARVHLHIPEMIDELRALATETPPGADYPFVLMAGERRAYNANQIYRD
HHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCC
PTWRKVDPHGSLRIHPDDAAALGVADGGKLVCASATGSIEVVAELDDSVRRGMVTLPHGY
CCCCEECCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEEEEECHHHHHCCEEECCCCC
GMRYKGGPPVGPELNRLTSGAHCDPLSRTPYHKYVPVHLRVVDTPVAAPATLEAESA
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]