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The map label for this gene is otsA [H]

Identifier: 126451582

GI number: 126451582

Start: 2773457

End: 2774833

Strand: Reverse

Name: otsA [H]

Synonym: BURPS1106A_2814

Alternate gene names: 126451582

Gene position: 2774833-2773457 (Counterclockwise)

Preceding gene: 126452531

Following gene: 126455369

Centisome position: 69.57

GC content: 68.12

Gene sequence:

>1377_bases
ATGAGCCGTCTCATCATCGTCTCGAATCGGGTCGCGCCGATCTCCGAAGGAGAACCCGCGGCCGGCGGCCTCGCGATCGG
CGTCTACGACGCGCTGAAGGAAACGGGCGGCATGTGGTTCGGCTGGAGCGGCGAGGTGATCGCGTCGGGCGTGCCGCAGA
TCCGCATCGAGGAGCACGGCCCCGTCACGTTCGCGACGATCGGGCTGTCGCGCCGCGACTACGATCAGTACTACCGAGGC
TTTTCGAACGCGACGCTCTGGCCCGCGTTCCACTATCGCGCGGACCTGATCCAGTTCGACCGCCACGAGTTCGAAGGCTA
TTCGCGCGTGAACGTGTGGCTCGCGCAGCAGCTCGTGCCGCTGCTGCGCGATGACGACGTGATCTGGGTGCACGACTATC
ATCTGATTCCGTTCGCGCGGGCGCTGCGCACGGCGGGCGTGAAGAACCGCATCGGTTTTTTCCTGCATATTCCGTTTCCG
GCGGCGCAGGTGCTCGTCAACGTGCCGCCGCATCGCGAGCTGGTCGAGGCGCTGTGCTCGTTCGATCTGCTCGGCTTTCA
GACCGACACCGATCTGCGCGCGTTCTTCGAGTACGTCGAATACGAGGCGGGCGGCACGGTCGATCGCGCCGCGCATCCGG
CGCGCGTCGACGCGTTCGGCCGCACGCTGCGCGCGGCCGCGTATCCGATCGGCGTGTATCCGGACGAGATCGCCGCGCTC
GCGAAGGCGGGCGAGAACGGCCGCGCGGTGAAGTCGCTCGCGGCCTCGCTGCGCGGGCGGCAGCTCGTGATGAGCGTCGA
CCGGCTCGATTACTCGAAGGGGCTCGTCGAGCGCTTTCGCGCATTCGAGAAGCTGCTCGAGCACGAGACGTCGTTTCGCA
ATCGCGTGTCGTTCCTGCAGATCGCGCCGTCCACGCGCGCCGATCTGCGCGCGTACCAGGACATCCGCCGGCAGCTCGAG
GGCGAATCGGGGCGCATCAACGGCCGTTTCGCGGAGCTCGACTGGGCGCCGATCCTCTATATCCATCGGCAGTACGAACG
GCCGGTGCTCGCCGCGCTATACCGGCTCGCGCGCGTCGGGTACGTGACGCCGCTGCGCGACGGGATGAATCTCGTCGCGA
AGGAGTACGTGTCCGCGCAGGATCCGGACGATCCGGGCGTGCTCGTGCTGTCGCGCTTCGCGGGCGCCGCGTGCGAACTC
ACCGGCGCGTTGATCGTCAATCCGATCGACATCGGCGGGATGGCCGACGCGCTGTCGCGCGCGCTGTCGATGCCGCTCGC
CGAGCGGCGCGCGCGCCACGCCGACATGCTCGCGCGGTTGCGCGAGAACAACGTGTCGGTGTGGCGCGACCACTTCCTGC
GCGATCTCGGGCGGTAG

Upstream 100 bases:

>100_bases
AGGTCGGTGCGGGCGACACGACGGCGCGCGCGCGCGTCGATTCGGTCGCCGCGTTGCGCGCGCAGCTCGCGCGCTGGATC
GCCGCGGGGCGCGCGCCCGC

Downstream 100 bases:

>100_bases
CGCGCGGCGTCGGGGGCCGGCCGGGGTCGTTAGGCGTGCGCGACGATGCGCGCGTGCGGCTTTAAGCGACGCGCTCGTCG
TCCGACGACGAATCGTCGTC

Product: alpha,alpha-trehalose-phosphate synthase (UDP-forming)

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHGPVTFATIGLSRRDYDQYYRG
FSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFP
AAQVLVNVPPHRELVEALCSFDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQIAPSTRADLRAYQDIRRQLE
GESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVGYVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACEL
TGALIVNPIDIGGMADALSRALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGR

Sequences:

>Translated_458_residues
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHGPVTFATIGLSRRDYDQYYRG
FSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFP
AAQVLVNVPPHRELVEALCSFDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQIAPSTRADLRAYQDIRRQLE
GESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVGYVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACEL
TGALIVNPIDIGGMADALSRALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGR
>Mature_457_residues
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHGPVTFATIGLSRRDYDQYYRGF
SNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVPLLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFPA
AQVLVNVPPHRELVEALCSFDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAALA
KAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQIAPSTRADLRAYQDIRRQLEG
ESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVGYVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACELT
GALIVNPIDIGGMADALSRALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGR

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=458, Percent_Identity=52.8384279475983, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI115533560, Length=421, Percent_Identity=28.5035629453682, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115533558, Length=421, Percent_Identity=28.5035629453682, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71987012, Length=416, Percent_Identity=28.125, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319602, Length=470, Percent_Identity=31.4893617021277, Blast_Score=263, Evalue=4e-71,
Organism=Saccharomyces cerevisiae, GI6323537, Length=435, Percent_Identity=26.6666666666667, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320279, Length=396, Percent_Identity=25.2525252525253, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323917, Length=378, Percent_Identity=26.4550264550265, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI19920676, Length=489, Percent_Identity=35.5828220858896, Blast_Score=275, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 51410; Mature: 51279

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHG
CCCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCHHHCCCCEEEEECCC
PVTFATIGLSRRDYDQYYRGFSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVP
CEEEEEECCCCCCHHHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFPAAQVLVNVPPHRELVEALCS
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEEECCCHHHHHHHHHC
FDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
CHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQ
HHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
IAPSTRADLRAYQDIRRQLEGESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVG
ECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEHHHHCCHHHHHHHHHHHHC
YVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACELTGALIVNPIDIGGMADALSR
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHEECCEEEECCCCCCCHHHHHHH
ALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGR
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRLIIVSNRVAPISEGEPAAGGLAIGVYDALKETGGMWFGWSGEVIASGVPQIRIEEHG
CCEEEEECCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEECCCCCHHHCCCCEEEEECCC
PVTFATIGLSRRDYDQYYRGFSNATLWPAFHYRADLIQFDRHEFEGYSRVNVWLAQQLVP
CEEEEEECCCCCCHHHHHCCCCCCEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLRDDDVIWVHDYHLIPFARALRTAGVKNRIGFFLHIPFPAAQVLVNVPPHRELVEALCS
HHCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCHHHHEEECCCHHHHHHHHHC
FDLLGFQTDTDLRAFFEYVEYEAGGTVDRAAHPARVDAFGRTLRAAAYPIGVYPDEIAAL
CHHCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
AKAGENGRAVKSLAASLRGRQLVMSVDRLDYSKGLVERFRAFEKLLEHETSFRNRVSFLQ
HHCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
IAPSTRADLRAYQDIRRQLEGESGRINGRFAELDWAPILYIHRQYERPVLAALYRLARVG
ECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEHHHHCCHHHHHHHHHHHHC
YVTPLRDGMNLVAKEYVSAQDPDDPGVLVLSRFAGAACELTGALIVNPIDIGGMADALSR
CCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCHHEECCEEEECCCCCCCHHHHHHH
ALSMPLAERRARHADMLARLRENNVSVWRDHFLRDLGR
HHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA