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The map label for this gene is namA [H]

Identifier: 126451506

GI number: 126451506

Start: 3985212

End: 3986324

Strand: Reverse

Name: namA [H]

Synonym: BURPS1106A_4082

Alternate gene names: 126451506

Gene position: 3986324-3985212 (Counterclockwise)

Preceding gene: 126453019

Following gene: 126454312

Centisome position: 99.95

GC content: 68.1

Gene sequence:

>1113_bases
ATGAGTGCATTGTTTTCTCCATTCACGCTGCGCGGCGTGACCCTTCCCAATCGCATCGTGATTTCGCCGATGTGCCAGTA
TTCGGCCGAAAACGGCGAGGCGCGCGCGTGGCACATGATTCATCTCGGGCATCTCGCGTTGTCCGGCGCGGGGCTGCTTT
GCATCGAAGCGACGGCCGTCGAGCCCGACGGCCGCATTTCGGCCGCGGATCTCGGCTTGTGGAGCGACGCGACCGAGGCC
GCGCTCGAACCCGTGCTCGCGGCGATCCGCAAGCATTCGCCGATTCGCGTCGCGATGCAGCTGTCGCACGCGGGCCGCAA
GGCGTCGAGCGACGTGCCGTGGAAAGGCGGCCAGTTGATTGCCGTCGATGAGGGCGGCTGGCGGCCGCATGCGCCTTCCG
GCGTCCCGCACCGGGAGCATGAGCCCACGCCGCTCGCGCTCGATGCGGCGGGGCTCGAGCGCGTGAAGCGCGCGTTCGTC
GAATCCGCGAAACGCGCGGCGCGTCTTGGCATCGACGCGATCGAAGTCCACGCGGCGCACGGCTATTTGCTGCATCAGTT
CCTGTCGCCGCTCGCGAACCATCGCGACGATGCGTACGGCGGCTCGCTCGAAAACCGGATGCGCTTTCCGCTCGAGGTAT
TCGACGCGGTGCGCGCGGCGTTTCCGGACGATCGTCCGGTCGGCGTGCGCGTGTCCGCGACCGACTGGGTGTCGGGCGGC
TGGGAGCTCGACGATACGCTCGCGTTCGCGCACGAACTGAAGCGGCGCGATTGCGATTGGATCGACGTGTCATCGGGCGG
TGTGTCGCCGCTTCAGAAAATTCCGTTGTCGCCCGGCTATCAGGTGCCGTTCGCGCAGGCGGTCAAGCGCGCGGTCGGGC
TGCCGACGATCGCCGTCGGCCTCATTTCCGATCCCGCGCATGCGAATCGCGTGATCGAAGCGGGTGACGCGGACTTCGTC
GCGATGGCGCGCGCGATGCTCTACGATCCGCGCTGGCCGTGGCATGCGGCCGCGCAGCTCGGCGCGACGGTCAGTGCGCC
GCCGCAGTATTGGCGCTCGCAGCCGCGCGAGTACAAGGCGCTGTTCGGCGACGCATCGTTCGGCCAGCGCTGA

Upstream 100 bases:

>100_bases
CGGGTGCCGTTTCCCTTTCGTGCGCCATCGGCGCCTGCGGCAAGCTTTTGTGCTGCGTGCTAACCTCGGCCGCTCGACTT
CCCTTGTGAGGGCGGCTGCC

Downstream 100 bases:

>100_bases
ACGCCGCGCGCGACGCATGGAGGCGAGCCGCCGGTGCGCGGCTCGCATGCCGATTTCGAGCGCGCTGTTTCGATTGCCGA
TGCGGGCGATGTTTCGCCAT

Product: oxidoreductase, FAD/FMN-binding

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSALFSPFTLRGVTLPNRIVISPMCQYSAENGEARAWHMIHLGHLALSGAGLLCIEATAVEPDGRISAADLGLWSDATEA
ALEPVLAAIRKHSPIRVAMQLSHAGRKASSDVPWKGGQLIAVDEGGWRPHAPSGVPHREHEPTPLALDAAGLERVKRAFV
ESAKRAARLGIDAIEVHAAHGYLLHQFLSPLANHRDDAYGGSLENRMRFPLEVFDAVRAAFPDDRPVGVRVSATDWVSGG
WELDDTLAFAHELKRRDCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVGLPTIAVGLISDPAHANRVIEAGDADFV
AMARAMLYDPRWPWHAAAQLGATVSAPPQYWRSQPREYKALFGDASFGQR

Sequences:

>Translated_370_residues
MSALFSPFTLRGVTLPNRIVISPMCQYSAENGEARAWHMIHLGHLALSGAGLLCIEATAVEPDGRISAADLGLWSDATEA
ALEPVLAAIRKHSPIRVAMQLSHAGRKASSDVPWKGGQLIAVDEGGWRPHAPSGVPHREHEPTPLALDAAGLERVKRAFV
ESAKRAARLGIDAIEVHAAHGYLLHQFLSPLANHRDDAYGGSLENRMRFPLEVFDAVRAAFPDDRPVGVRVSATDWVSGG
WELDDTLAFAHELKRRDCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVGLPTIAVGLISDPAHANRVIEAGDADFV
AMARAMLYDPRWPWHAAAQLGATVSAPPQYWRSQPREYKALFGDASFGQR
>Mature_369_residues
SALFSPFTLRGVTLPNRIVISPMCQYSAENGEARAWHMIHLGHLALSGAGLLCIEATAVEPDGRISAADLGLWSDATEAA
LEPVLAAIRKHSPIRVAMQLSHAGRKASSDVPWKGGQLIAVDEGGWRPHAPSGVPHREHEPTPLALDAAGLERVKRAFVE
SAKRAARLGIDAIEVHAAHGYLLHQFLSPLANHRDDAYGGSLENRMRFPLEVFDAVRAAFPDDRPVGVRVSATDWVSGGW
ELDDTLAFAHELKRRDCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVGLPTIAVGLISDPAHANRVIEAGDADFVA
MARAMLYDPRWPWHAAAQLGATVSAPPQYWRSQPREYKALFGDASFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=30.0859598853868, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789463, Length=337, Percent_Identity=27.299703264095, Blast_Score=105, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=299, Percent_Identity=27.7591973244147, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17564188, Length=230, Percent_Identity=30.8695652173913, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559804, Length=230, Percent_Identity=31.304347826087, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559802, Length=178, Percent_Identity=35.3932584269663, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540738, Length=202, Percent_Identity=31.1881188118812, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17565138, Length=272, Percent_Identity=27.2058823529412, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=247, Percent_Identity=26.7206477732794, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=267, Percent_Identity=28.8389513108614, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=264, Percent_Identity=29.1666666666667, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40075; Mature: 39944

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALFSPFTLRGVTLPNRIVISPMCQYSAENGEARAWHMIHLGHLALSGAGLLCIEATAV
CCCCCCCCEEEEECCCCEEEECHHHHCCCCCCCCEEEEEEEEHHHHHCCCCEEEEEEEEE
EPDGRISAADLGLWSDATEAALEPVLAAIRKHSPIRVAMQLSHAGRKASSDVPWKGGQLI
CCCCCEEHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCEEE
AVDEGGWRPHAPSGVPHREHEPTPLALDAAGLERVKRAFVESAKRAARLGIDAIEVHAAH
EECCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
GYLLHQFLSPLANHRDDAYGGSLENRMRFPLEVFDAVRAAFPDDRPVGVRVSATDWVSGG
HHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
WELDDTLAFAHELKRRDCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVGLPTIAVG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEE
LISDPAHANRVIEAGDADFVAMARAMLYDPRWPWHAAAQLGATVSAPPQYWRSQPREYKA
ECCCCHHHCCEEECCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHCCCHHHHH
LFGDASFGQR
HCCCCCCCCC
>Mature Secondary Structure 
SALFSPFTLRGVTLPNRIVISPMCQYSAENGEARAWHMIHLGHLALSGAGLLCIEATAV
CCCCCCCEEEEECCCCEEEECHHHHCCCCCCCCEEEEEEEEHHHHHCCCCEEEEEEEEE
EPDGRISAADLGLWSDATEAALEPVLAAIRKHSPIRVAMQLSHAGRKASSDVPWKGGQLI
CCCCCEEHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCCCCCCCCCEEE
AVDEGGWRPHAPSGVPHREHEPTPLALDAAGLERVKRAFVESAKRAARLGIDAIEVHAAH
EECCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
GYLLHQFLSPLANHRDDAYGGSLENRMRFPLEVFDAVRAAFPDDRPVGVRVSATDWVSGG
HHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
WELDDTLAFAHELKRRDCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVGLPTIAVG
CCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEE
LISDPAHANRVIEAGDADFVAMARAMLYDPRWPWHAAAQLGATVSAPPQYWRSQPREYKA
ECCCCHHHCCEEECCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHCCCHHHHH
LFGDASFGQR
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA