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The map label for this gene is xdhB [H]

Identifier: 126451487

GI number: 126451487

Start: 3113044

End: 3115407

Strand: Reverse

Name: xdhB [H]

Synonym: BURPS1106A_3198

Alternate gene names: 126451487

Gene position: 3115407-3113044 (Counterclockwise)

Preceding gene: 126452264

Following gene: 126454097

Centisome position: 78.11

GC content: 70.22

Gene sequence:

>2364_bases
ATGAATCAGCAAGCCGAACCTTTCCTGAGCGTCGCCGCCGATGCCGAGCGCGACGCGTTCCGGCAGGTCCACGTCTCGCG
GCCGCATGAATCCGCGCATCTGCACGTGAGCGGGCGCGCCACCTACATCGACGACATCCCGCTCGTCGCGGGCACGCTGC
ACGCGGCGCTCGGCCTGTCCGCGAAGCCGCACGCGCGGATCGCGTCGATGCGGCTCGACGCGGTGCGCGCAGCGGCGGGC
GTCGTCGCGGTGCTGACCGCGGCCGACATTCCGGGCACGAACGATTGCGGGCCGATCGTCCACGACGATCCGGTGCTTGC
CGACGGCGTCGTTCAATACGTCGGGCAGCCGATGTTCGTCGTCGTCGCGACGTCGCACGACGCCGCGCGCCGCGCCGCGC
GTCTCGCGCAGATCGAATACGAAGAACGGCCGGCGATCCTGACCGCGCAGGCGGCGCGCGCGGCCGATTCGTACGTATTG
CCGCCGATGCGGCTCGCGCGCGGCGACGCGGCCGCGCGGATCGCGCACGCCGCGCATCGCGACGCGGGCGAGCTCACGCT
GGGCGGCCAGGAGCAGTTCTATCTCGAAGGGCAAATCGCCTACGCGGTGCCGAAGGAAGACGGCGCGATGCACGTCTACA
GCTCGACGCAGCACCCGAGCGAGATGCAGCATCTCGTCGCGCACGCGCTGGGGCTCGCGTCGCACGACGTGCTCGTCGAA
TGCCGGCGCATGGGGGGCGGCTTCGGCGGCAAGGAATCGCAATCGGGCCTGTTCGCGTGCTGCGCCGCGCTCGCCGCATG
GAAGCTGCAACGCCCGGTGAAGCTGCGCCCCGATCGCGACGACGACATGATGATCACCGGCAAGCGGCACGATTTCCATT
ACCGCTACGACGTGGGCTACGACGACGCGGGCGTGATCGAGGGCGTCTCGGTCGACATGACGTCGCGCTGCGGCTTCTCC
GCCGATCTGTCGGGGCCCGTGATGACGCGCGCCGTGTGCCACTTCGACAACGCGTACTGGCTGCCCGACGTATCGATCGT
CGGCCGCTGCGGGAAGACGAACACGCAGTCGAACACTGCGTTTCGCGGCTTCGGCGGCCCCCAGGGCGCGTTCGCGATCG
AGTACATCGTCGACAGCGTCGCGCGCGCGCTCGGCCGCGATCCGCTCGACGTGCGCCGCGCGAACCTGTACGGCAAGACC
GAGCGCAACGTGACGCCGTACGGCCAGACGATCGAGGACAACGTGCTGCCCGAGCTGATCGCCGAGCTCGAGGCGACGAG
CGCGTATCGCGCGCGCCGCGCGGCGACGCGCGCGTTCAACGCGGCGAGCCCGGTGCTGAAGAAGGGCATCGCGCTCACGC
CGGTGAAGTTCGGCATTGCGTTCAACGTCACGCATTTCAACCAGGCGGGCGCGCTCGTTCACATCTATACCGACGGCTCG
ATCCTCGTGAACCACGGCGGCACGGAGATGGGCCAGGGGCTCAACACGAAGGTCGCGCAGGTCGTCGCGCACGAGCTCGG
CGTGGACTTCGCGCGCATTCGCGTGACGGCGACCGACACGAGCAAGGTCGCGAACACATCGGCGACGGCCGCGTCGACGG
GTTCCGACCTGAACGGCAAGGCCGCGCAGGACGCCGCGCGGCAGTTGCGCGAGCGGCTCGCCGCGTTCGCGGCCGAGCAT
GTCGGCGGCGGCGCGGCGCGCGCGGCCGACGTGCGCTTCGCGCACGACGAGGTGCGCGTGGGCGAGGTGGCCGTGCCGTT
CGAGGAACTCGTCGCGCACGCGTATCGCGCGCGCGTGCAGCTGTGGTCGGACGGCTTTTACGCGACGCCGAAGCTGCACT
GGGATCAGGCGGCGCTGCGCGGGCGGCCGTTCTTCTATTACGCGTACGGCGCGGCGGTCTCCGAGGTCGTCGTCGACACG
CTGACGGGCGAGATGCGTGTGCTGCGAGCGGATGCGCTGCACGACGTCGGTGCGTCGCTGAATCCGGCGCTCGACATCGG
GCAGGTCGAGGGCGCGTTCATCCAGGGAATGGGGTGGCTCACGACCGAGGAGCTGTGGTGGAACGACGGCGGCAGGCTGA
TGACGCACGCGCCGTCGACGTACAAGATCCCGACCGTCAACGATTGTCCGCCGGATTTCCGCGTGAGACTGTTCGACAAC
CGCAACGCGGAGGACAGCATTCACCGGTCGAAGGCGGTCGGCGAGCCGCCGCTGTTGCTGCCGTTCTCGGTGTTCTTCGC
GATCCGCGACGCGATCGCGGCGGTGGGCGATTACGCGGTCAATCCGCCGCTCGCCGCACCCGCGACGGGCGAGTCGATCC
TGCGCGCGGTGCGGGCGGTGCGCGCGGCGCGGGCCGGGGCGTGA

Upstream 100 bases:

>100_bases
CGCCCGCACGATCCGCTGCCCGCGTCGGCCGTGAACGTGCGCGAAGTGGCCGCCGAGCCGGCCGCCTCCTGACCGATCGA
CGCCAAGCGGAGCCATCGCA

Downstream 100 bases:

>100_bases
CGCGGGACGGTTGCGCGGCGGGGGGACGGACGGCGCGCATCGGCGCATGCGGGGCAAGTGCGGCGGGCACGGCGGGCGCA
AGACTTCAGAGACGCGAGAT

Product: xanthine dehydrogenase, molybdopterin binding subunit

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 787; Mature: 787

Protein sequence:

>787_residues
MNQQAEPFLSVAADAERDAFRQVHVSRPHESAHLHVSGRATYIDDIPLVAGTLHAALGLSAKPHARIASMRLDAVRAAAG
VVAVLTAADIPGTNDCGPIVHDDPVLADGVVQYVGQPMFVVVATSHDAARRAARLAQIEYEERPAILTAQAARAADSYVL
PPMRLARGDAAARIAHAAHRDAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHALGLASHDVLVE
CRRMGGGFGGKESQSGLFACCAALAAWKLQRPVKLRPDRDDDMMITGKRHDFHYRYDVGYDDAGVIEGVSVDMTSRCGFS
ADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTAFRGFGGPQGAFAIEYIVDSVARALGRDPLDVRRANLYGKT
ERNVTPYGQTIEDNVLPELIAELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAEH
VGGGAARAADVRFAHDEVRVGEVAVPFEELVAHAYRARVQLWSDGFYATPKLHWDQAALRGRPFFYYAYGAAVSEVVVDT
LTGEMRVLRADALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNDGGRLMTHAPSTYKIPTVNDCPPDFRVRLFDN
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAIAAVGDYAVNPPLAAPATGESILRAVRAVRAARAGA

Sequences:

>Translated_787_residues
MNQQAEPFLSVAADAERDAFRQVHVSRPHESAHLHVSGRATYIDDIPLVAGTLHAALGLSAKPHARIASMRLDAVRAAAG
VVAVLTAADIPGTNDCGPIVHDDPVLADGVVQYVGQPMFVVVATSHDAARRAARLAQIEYEERPAILTAQAARAADSYVL
PPMRLARGDAAARIAHAAHRDAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHALGLASHDVLVE
CRRMGGGFGGKESQSGLFACCAALAAWKLQRPVKLRPDRDDDMMITGKRHDFHYRYDVGYDDAGVIEGVSVDMTSRCGFS
ADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTAFRGFGGPQGAFAIEYIVDSVARALGRDPLDVRRANLYGKT
ERNVTPYGQTIEDNVLPELIAELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAEH
VGGGAARAADVRFAHDEVRVGEVAVPFEELVAHAYRARVQLWSDGFYATPKLHWDQAALRGRPFFYYAYGAAVSEVVVDT
LTGEMRVLRADALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNDGGRLMTHAPSTYKIPTVNDCPPDFRVRLFDN
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAIAAVGDYAVNPPLAAPATGESILRAVRAVRAARAGA
>Mature_787_residues
MNQQAEPFLSVAADAERDAFRQVHVSRPHESAHLHVSGRATYIDDIPLVAGTLHAALGLSAKPHARIASMRLDAVRAAAG
VVAVLTAADIPGTNDCGPIVHDDPVLADGVVQYVGQPMFVVVATSHDAARRAARLAQIEYEERPAILTAQAARAADSYVL
PPMRLARGDAAARIAHAAHRDAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHALGLASHDVLVE
CRRMGGGFGGKESQSGLFACCAALAAWKLQRPVKLRPDRDDDMMITGKRHDFHYRYDVGYDDAGVIEGVSVDMTSRCGFS
ADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTAFRGFGGPQGAFAIEYIVDSVARALGRDPLDVRRANLYGKT
ERNVTPYGQTIEDNVLPELIAELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGKAAQDAARQLRERLAAFAAEH
VGGGAARAADVRFAHDEVRVGEVAVPFEELVAHAYRARVQLWSDGFYATPKLHWDQAALRGRPFFYYAYGAAVSEVVVDT
LTGEMRVLRADALHDVGASLNPALDIGQVEGAFIQGMGWLTTEELWWNDGGRLMTHAPSTYKIPTVNDCPPDFRVRLFDN
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAIAAVGDYAVNPPLAAPATGESILRAVRAVRAARAGA

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG4631

COG function: function code F; Xanthine dehydrogenase, molybdopterin-binding subunit B

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=757, Percent_Identity=42.9326287978864, Blast_Score=588, Evalue=1e-168,
Organism=Homo sapiens, GI71773480, Length=748, Percent_Identity=37.1657754010695, Blast_Score=465, Evalue=1e-131,
Organism=Escherichia coli, GI1789230, Length=748, Percent_Identity=28.2085561497326, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1789246, Length=775, Percent_Identity=26.1935483870968, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1786478, Length=738, Percent_Identity=25.0677506775068, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540638, Length=770, Percent_Identity=40.1298701298701, Blast_Score=503, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI32566215, Length=710, Percent_Identity=31.6901408450704, Blast_Score=332, Evalue=6e-91,
Organism=Caenorhabditis elegans, GI17539860, Length=720, Percent_Identity=31.5277777777778, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI17737937, Length=763, Percent_Identity=42.2018348623853, Blast_Score=563, Evalue=1e-160,
Organism=Drosophila melanogaster, GI24647199, Length=763, Percent_Identity=32.2411533420708, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24647193, Length=767, Percent_Identity=31.8122555410691, Blast_Score=332, Evalue=9e-91,
Organism=Drosophila melanogaster, GI24647201, Length=762, Percent_Identity=32.6771653543307, Blast_Score=320, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24647195, Length=774, Percent_Identity=30.2325581395349, Blast_Score=288, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24647197, Length=774, Percent_Identity=30.2325581395349, Blast_Score=287, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 84442; Mature: 84442

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQAEPFLSVAADAERDAFRQVHVSRPHESAHLHVSGRATYIDDIPLVAGTLHAALGLS
CCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCC
AKPHARIASMRLDAVRAAAGVVAVLTAADIPGTNDCGPIVHDDPVLADGVVQYVGQPMFV
CCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEE
VVATSHDAARRAARLAQIEYEERPAILTAQAARAADSYVLPPMRLARGDAAARIAHAAHR
EEECCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCC
DAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHALGLASHDVLVE
CCCCEEECCCCEEEEECEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHH
CRRMGGGFGGKESQSGLFACCAALAAWKLQRPVKLRPDRDDDMMITGKRHDFHYRYDVGY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEECCC
DDAGVIEGVSVDMTSRCGFSADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTA
CCCCCCCCCEECHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCHHHHCCCCCCCCCCCCE
FRGFGGPQGAFAIEYIVDSVARALGRDPLDVRRANLYGKTERNVTPYGQTIEDNVLPELI
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
AELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCE
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGK
EEEECCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCH
AAQDAARQLRERLAAFAAEHVGGGAARAADVRFAHDEVRVGEVAVPFEELVAHAYRARVQ
HHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEECCCEEECEEECCHHHHHHHHHHHHHE
LWSDGFYATPKLHWDQAALRGRPFFYYAYGAAVSEVVVDTLTGEMRVLRADALHDVGASL
EECCCEEECCCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCC
NPALDIGQVEGAFIQGMGWLTTEELWWNDGGRLMTHAPSTYKIPTVNDCPPDFRVRLFDN
CCCCCCCCCCCHHHCCCCCCEEHHEEECCCCEEEEECCCCEECCCCCCCCCCCEEEEECC
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAIAAVGDYAVNPPLAAPATGESILRAVRAV
CCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
RAARAGA
HHHHCCC
>Mature Secondary Structure
MNQQAEPFLSVAADAERDAFRQVHVSRPHESAHLHVSGRATYIDDIPLVAGTLHAALGLS
CCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCC
AKPHARIASMRLDAVRAAAGVVAVLTAADIPGTNDCGPIVHDDPVLADGVVQYVGQPMFV
CCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEE
VVATSHDAARRAARLAQIEYEERPAILTAQAARAADSYVLPPMRLARGDAAARIAHAAHR
EEECCCHHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCC
DAGELTLGGQEQFYLEGQIAYAVPKEDGAMHVYSSTQHPSEMQHLVAHALGLASHDVLVE
CCCCEEECCCCEEEEECEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHH
CRRMGGGFGGKESQSGLFACCAALAAWKLQRPVKLRPDRDDDMMITGKRHDFHYRYDVGY
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCEEEEEECCC
DDAGVIEGVSVDMTSRCGFSADLSGPVMTRAVCHFDNAYWLPDVSIVGRCGKTNTQSNTA
CCCCCCCCCEECHHHCCCCCCCCCCCHHHHHHHHCCCCEECCCHHHHCCCCCCCCCCCCE
FRGFGGPQGAFAIEYIVDSVARALGRDPLDVRRANLYGKTERNVTPYGQTIEDNVLPELI
EECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
AELEATSAYRARRAATRAFNAASPVLKKGIALTPVKFGIAFNVTHFNQAGALVHIYTDGS
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEECEEEEEEEEEEEEECCCCCEEEEEECCE
ILVNHGGTEMGQGLNTKVAQVVAHELGVDFARIRVTATDTSKVANTSATAASTGSDLNGK
EEEECCCHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHCCCCCCCCCCCCCCCCH
AAQDAARQLRERLAAFAAEHVGGGAARAADVRFAHDEVRVGEVAVPFEELVAHAYRARVQ
HHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEECCCEEECEEECCHHHHHHHHHHHHHE
LWSDGFYATPKLHWDQAALRGRPFFYYAYGAAVSEVVVDTLTGEMRVLRADALHDVGASL
EECCCEEECCCCCCCHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCC
NPALDIGQVEGAFIQGMGWLTTEELWWNDGGRLMTHAPSTYKIPTVNDCPPDFRVRLFDN
CCCCCCCCCCCHHHCCCCCCEEHHEEECCCCEEEEECCCCEECCCCCCCCCCCEEEEECC
RNAEDSIHRSKAVGEPPLLLPFSVFFAIRDAIAAVGDYAVNPPLAAPATGESILRAVRAV
CCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
RAARAGA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]