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The map label for this gene is yafC [C]

Identifier: 126451470

GI number: 126451470

Start: 145386

End: 146441

Strand: Direct

Name: yafC [C]

Synonym: BURPS1106A_0153

Alternate gene names: 126451470

Gene position: 145386-146441 (Clockwise)

Preceding gene: 126454609

Following gene: 126453149

Centisome position: 3.65

GC content: 67.23

Gene sequence:

>1056_bases
ATGGATCATTTGCAGTCGATGCGAGTGTTCGTCAAGGTCGCGGATCTCGGCAGTTTCGCCCGGGCGGCGAGCGCGATGGA
CATCTCGAATGCGGTCGCGACGCGCCACGTCGCCGACCTCGAAGGCCGGCTCGGCACCCGCCTTCTGAATCGCACCACCC
GAAGCCTGTCGCTGACCGAATCCGGCCAAGTTTACCTGGAGCGGGCGCGCCAGATCCTCGACGAACTCGAAGACGTCGAG
CAGATGGTCGTCGCGCGCAATCACGAGCCCGTCGGCACGCTGCGGGTCGTCGCGCCCGTCGTGTTCGGCCTGCACAATCT
CGCGCCGGTCTTGCAGACGTATACGCAGCGTTTCCCGAAGGTCATCCCCGACCTGACCCTCGTCGATCGTCAGGTCGATC
TCGTCGAAGAGGGGTTCGACGTCGGCATCGTGATCACGCGGCAGATGCGCAGTGCGAGCATCGTCACGCGCCGGCTGACC
ACGGGCTGCATGGTGGTCTGCGCGACGCCGAGCTACCTGGAGAAGCACGGCATGCCGACGCATCCGGAGCAACTCGTCGA
GCATCCTTGCCTGAGCCTGCCGTCCGAATATTGGGGAGACGAGCGCGTATTCACCGGGCCGGACGGCGAAGTGCGCGTAC
GGCCGTCGAACGTCGTCGTCGCGAACAACACCGAGATGCTGCGCCAGTTCGCGATGCTCGGCATGGGCGTCGCGATCCTG
CCGAGCTATCTGATCGGCAGCGACATCGCGCGCGGCAAGCTCGTGCGCTTGCTGAGCGACTACCGGCTGCCGCAGGTCGA
GATCAATATCGCGTACCCGAGCCGCCGCCACCTGCCGGCGAAGGTGCGCACGTTCATCGACCATCTCGTCGAGCACTTCA
GCCAATCGCCGGACACGATGCTCGGCGAGCAATGGGCGACGCAGGGCGTCGCGGGCCAGCACGTCGATGCGCTGCCCGCC
GACGCGCTCGCCGAGCGCTCGAGCGCCGATCCGGCGCTGTCGCCGCGTCTGCCGCGCGCGCCGCGGGCGCGCACCGTCGT
GCCGTCTCCGCTGTAA

Upstream 100 bases:

>100_bases
TTCGCGGGAAGTTGAGCAACTCTGCATCTTTTTCGCTGTCGTAGGAAAATTACTCATTTGCTTCATATTTTTGAAGCTGT
AACAGCGGTAGGAGCGGAGT

Downstream 100 bases:

>100_bases
CGCCGAGCGGATGTCGCGCATGCACTGATCCTGCGCGCACGCAGGCCGTCGCACGCCGAATCTCCTACGCCAAAAGCAAA
AGCGCGGGCTCGTCGAGAGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRVVAPVVFGLHNLAPVLQTYTQRFPKVIPDLTLVDRQVDLVEEGFDVGIVITRQMRSASIVTRRLT
TGCMVVCATPSYLEKHGMPTHPEQLVEHPCLSLPSEYWGDERVFTGPDGEVRVRPSNVVVANNTEMLRQFAMLGMGVAIL
PSYLIGSDIARGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSQSPDTMLGEQWATQGVAGQHVDALPA
DALAERSSADPALSPRLPRAPRARTVVPSPL

Sequences:

>Translated_351_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRVVAPVVFGLHNLAPVLQTYTQRFPKVIPDLTLVDRQVDLVEEGFDVGIVITRQMRSASIVTRRLT
TGCMVVCATPSYLEKHGMPTHPEQLVEHPCLSLPSEYWGDERVFTGPDGEVRVRPSNVVVANNTEMLRQFAMLGMGVAIL
PSYLIGSDIARGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSQSPDTMLGEQWATQGVAGQHVDALPA
DALAERSSADPALSPRLPRAPRARTVVPSPL
>Mature_351_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRVVAPVVFGLHNLAPVLQTYTQRFPKVIPDLTLVDRQVDLVEEGFDVGIVITRQMRSASIVTRRLT
TGCMVVCATPSYLEKHGMPTHPEQLVEHPCLSLPSEYWGDERVFTGPDGEVRVRPSNVVVANNTEMLRQFAMLGMGVAIL
PSYLIGSDIARGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSQSPDTMLGEQWATQGVAGQHVDALPA
DALAERSSADPALSPRLPRAPRARTVVPSPL

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=33.3333333333333, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=32.6530612244898, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87081978, Length=304, Percent_Identity=31.25, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=28.8659793814433, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=27.8145695364238, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1789440, Length=259, Percent_Identity=29.7297297297297, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=28.6206896551724, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=29.1828793774319, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1790011, Length=299, Percent_Identity=23.4113712374582, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI157672245, Length=142, Percent_Identity=28.169014084507, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787879, Length=151, Percent_Identity=30.4635761589404, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=289, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786448, Length=300, Percent_Identity=23.6666666666667, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788706, Length=262, Percent_Identity=24.4274809160305, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87082132, Length=285, Percent_Identity=23.1578947368421, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790262, Length=263, Percent_Identity=26.2357414448669, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788297, Length=143, Percent_Identity=27.972027972028, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI2367136, Length=298, Percent_Identity=28.1879194630872, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38828; Mature: 38828

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRVVAPVVFGLHNLAPVLQTYTQRFPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIPDLTLVDRQVDLVEEGFDVGIVITRQMRSASIVTRRLTTGCMVVCATPSYLEKHGMPT
HCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCEEEEECCHHHHHHCCCCC
HPEQLVEHPCLSLPSEYWGDERVFTGPDGEVRVRPSNVVVANNTEMLRQFAMLGMGVAIL
CHHHHHHCHHHCCCHHHCCCCCEEECCCCCEEECCCCEEEECCHHHHHHHHHHHCCHHHH
PSYLIGSDIARGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSQSPDTM
HHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHH
LGEQWATQGVAGQHVDALPADALAERSSADPALSPRLPRAPRARTVVPSPL
HHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRVVAPVVFGLHNLAPVLQTYTQRFPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIPDLTLVDRQVDLVEEGFDVGIVITRQMRSASIVTRRLTTGCMVVCATPSYLEKHGMPT
HCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCEEEEECCHHHHHHCCCCC
HPEQLVEHPCLSLPSEYWGDERVFTGPDGEVRVRPSNVVVANNTEMLRQFAMLGMGVAIL
CHHHHHHCHHHCCCHHHCCCCCEEECCCCCEEECCCCEEEECCHHHHHHHHHHHCCHHHH
PSYLIGSDIARGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFSQSPDTM
HHHHHHCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHH
LGEQWATQGVAGQHVDALPADALAERSSADPALSPRLPRAPRARTVVPSPL
HHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]