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The map label for this gene is dctD-2 [H]

Identifier: 126447915

GI number: 126447915

Start: 71818

End: 73164

Strand: Direct

Name: dctD-2 [H]

Synonym: BMA10247_A0086

Alternate gene names: 126447915

Gene position: 71818-73164 (Clockwise)

Preceding gene: 126446216

Following gene: 126445819

Centisome position: 3.05

GC content: 66.89

Gene sequence:

>1347_bases
ATGATGAACGCAGATAACGCTTATGGCCGCGAGGCCGTCTATGTGATCGAGGACGACGCGGCCGTGCGGTTGGGATGTTC
GCAGGCGCTCGCGCTCGAAGGCATCGGCGTGCGGGAGTTCGAGGACGCCGAGAGCGCCCTCGCCGCGCTCAAGCGCGACC
CGCCTGCGGCGATCGTCAGCGACGTCAGGCTGCCCGGCATGGGCGGCCTCGCGCTGCTCGACAGCATGAAGGCCCACCCC
CGGCATGCCGACATACCGGTCATCCTGATGACGGGGCATGGCGACGTGGCGATGGCCGTGGGGGCGATGCGCTGCGGCGC
GTACGATTTCATCGAGAAGCCGTTTCATTCCGATCGGCTCGTCGACACGGTCCGCCGCGCGTTGGAGCACCGCAAGCTCG
TGATCGAGAATCGCAGTCTTCGCGCGCAACTGAGCGGCGAGCGGCCGTTGCTCGGGAGCGCGCCCGCGATGCAGCGCGTC
CATGCGCTCATCGACGCTATCGGCCCCACCAGCGCCGATGTCCTGATCATCGGCGAGACCGGGACGGGAAAGGAGGTGCT
GGCGCGGGCGCTGCACGCGGCGAGCCGCCGCACCGGGCCGTTCGTGGCGCTCAATTGCGCCGCGCTGCCCGAGGCCGTGT
TCGAGAGCGAGATCTTCGGGCATGAGCCGGGGGCTTTCACCGGCGCTCAGCAGCGGCGCATCGGCAAGTTCGAATACGCA
AGCGGCGGCACGCTGTTCCTCGACGAGCTCGAGTCGATGCCTTTGTCGCTTCAGGCCAAGCTCTTGCGCGCGCTTCAGGA
GCGCAGCATCGAGCGGCTCGGCAGCAATGTCTCCGTCGCCGTCGACGTGCGGGTGATCGCCGCGGTCAAGCAGGACCTGA
AACAGCTCGCCGCCGACGGCCTGTTCCGGTCCGATCTGTATTTCCGGCTGAACGTGGCGTCGATCGAGCTGCCGCCGTTG
CGCCGGCGCACGGACGATATCCCGGAGCTCTTCAGTCATTTCCTCCGCGCCGCCGCCGTCAGGTTCGAAAAGCCTGAACC
GGTCTGGACGCAGGAAGACATGATGCGTTGGCAGCTTTACGACTGGCCGGGCAACGTGCGCGAGCTGAAAAACACGGCGG
AGCGGTTTTGCCTCGGTCTCGAAGACGGCTTGCCGCGCTCGCCGGCCGGATTCGATTCGCTCGCGTCGCGTATGGTCAGC
GCCGAGCGCGCGTATATCGAGGAAGCGCTTCGCAACGCGGGCGGGCAGGTGGCCAAGGCGGCCGAGTTGCTCGGGCTGCC
GCGTAAAACGCTATACGACAAGATCACGCGGCATGGCATCGATATGACGGCGTTTCGCTGCACGTGA

Upstream 100 bases:

>100_bases
GGGCGGCTGCACGCGAGAAACGGCAGCGGTGTCGAGCCCGAGTTGGGCGGCGCCGTTTTCATCGTCGAATTGCACCGCGT
ATCGAGAAAGTTTTCTTCCC

Downstream 100 bases:

>100_bases
CGCGTTTCGCGACGCGCGTCGATGGGGCGGGCGCGAAACCCGTTCGCCGCGATGCGGCGGACGGGGTATGGCCGAGCGCC
GTCCGTCGCGGCGAGAGTTG

Product: C4-dicarboxylate transport transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPAAIVSDVRLPGMGGLALLDSMKAHP
RHADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIENRSLRAQLSGERPLLGSAPAMQRV
HALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFESEIFGHEPGAFTGAQQRRIGKFEYA
SGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQLAADGLFRSDLYFRLNVASIELPPL
RRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERFCLGLEDGLPRSPAGFDSLASRMVS
AERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT

Sequences:

>Translated_448_residues
MMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPAAIVSDVRLPGMGGLALLDSMKAHP
RHADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIENRSLRAQLSGERPLLGSAPAMQRV
HALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFESEIFGHEPGAFTGAQQRRIGKFEYA
SGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQLAADGLFRSDLYFRLNVASIELPPL
RRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERFCLGLEDGLPRSPAGFDSLASRMVS
AERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT
>Mature_448_residues
MMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPAAIVSDVRLPGMGGLALLDSMKAHP
RHADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRLVDTVRRALEHRKLVIENRSLRAQLSGERPLLGSAPAMQRV
HALIDAIGPTSADVLIIGETGTGKEVLARALHAASRRTGPFVALNCAALPEAVFESEIFGHEPGAFTGAQQRRIGKFEYA
SGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQLAADGLFRSDLYFRLNVASIELPPL
RRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLYDWPGNVRELKNTAERFCLGLEDGLPRSPAGFDSLASRMVS
AERAYIEEALRNAGGQVAKAAELLGLPRKTLYDKITRHGIDMTAFRCT

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=40.1766004415011, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1790299, Length=477, Percent_Identity=40.8805031446541, Blast_Score=310, Evalue=9e-86,
Organism=Escherichia coli, GI1790437, Length=442, Percent_Identity=41.8552036199095, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1788905, Length=451, Percent_Identity=37.2505543237251, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI87082117, Length=337, Percent_Identity=43.9169139465875, Blast_Score=238, Evalue=4e-64,
Organism=Escherichia coli, GI1789087, Length=338, Percent_Identity=44.3786982248521, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1789233, Length=227, Percent_Identity=47.136563876652, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI1786524, Length=437, Percent_Identity=34.5537757437071, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI87082152, Length=227, Percent_Identity=47.5770925110132, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=46.0526315789474, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787583, Length=313, Percent_Identity=36.4217252396166, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI87081858, Length=294, Percent_Identity=33.3333333333333, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1789828, Length=238, Percent_Identity=37.8151260504202, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1786599, Length=170, Percent_Identity=28.8235294117647, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49078; Mature: 49078

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4 ; PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPAAIVS
CCCCCCCCCCEEEEEEECCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHH
DVRLPGMGGLALLDSMKAHPRHADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRL
CCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCHHH
VDTVRRALEHRKLVIENRSLRAQLSGERPLLGSAPAMQRVHALIDAIGPTSADVLIIGET
HHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
GTGKEVLARALHAASRRTGPFVALNCAALPEAVFESEIFGHEPGAFTGAQQRRIGKFEYA
CCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEC
SGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQLAADG
CCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCC
LFRSDLYFRLNVASIELPPLRRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLY
CCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEE
DWPGNVRELKNTAERFCLGLEDGLPRSPAGFDSLASRMVSAERAYIEEALRNAGGQVAKA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AELLGLPRKTLYDKITRHGIDMTAFRCT
HHHHCCCHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MMNADNAYGREAVYVIEDDAAVRLGCSQALALEGIGVREFEDAESALAALKRDPPAAIVS
CCCCCCCCCCEEEEEEECCCEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHH
DVRLPGMGGLALLDSMKAHPRHADIPVILMTGHGDVAMAVGAMRCGAYDFIEKPFHSDRL
CCCCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHCCCCCHHH
VDTVRRALEHRKLVIENRSLRAQLSGERPLLGSAPAMQRVHALIDAIGPTSADVLIIGET
HHHHHHHHHHHHEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECC
GTGKEVLARALHAASRRTGPFVALNCAALPEAVFESEIFGHEPGAFTGAQQRRIGKFEYA
CCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCEEEC
SGGTLFLDELESMPLSLQAKLLRALQERSIERLGSNVSVAVDVRVIAAVKQDLKQLAADG
CCCEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCC
LFRSDLYFRLNVASIELPPLRRRTDDIPELFSHFLRAAAVRFEKPEPVWTQEDMMRWQLY
CCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEEE
DWPGNVRELKNTAERFCLGLEDGLPRSPAGFDSLASRMVSAERAYIEEALRNAGGQVAKA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AELLGLPRKTLYDKITRHGIDMTAFRCT
HHHHCCCHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]