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The map label for this gene is mhpT [H]

Identifier: 126447673

GI number: 126447673

Start: 1734653

End: 1735945

Strand: Reverse

Name: mhpT [H]

Synonym: BMA10247_A1798

Alternate gene names: 126447673

Gene position: 1735945-1734653 (Counterclockwise)

Preceding gene: 126445641

Following gene: 126446207

Centisome position: 73.79

GC content: 73.32

Gene sequence:

>1293_bases
TTGAGGCAGGCGAAGCAAAACGACATCGACAACGATCGCATCGCAGCCGGCTCGCGCCGGCGCGAACGCGGCAGGTCTGG
AGACGAAATGGACATCACCGTGACGGAAAAGCGCGGCGTCGCGACGACGCTCGCGTTGTGCTTCGCGATCGCGCTGCTCG
AAGGGCTCGATCTGCAATCGGTCGGCGTCGCGGCGCCGCGCATGGCGCGCGAGTTCGGCCTGTCGGTCGCGCAGATGGGG
TGGGCGTTCGGCGCAGGCACGTTCGGCCTGCTGCCGGGGGCGCTGCTTGGCGGCCGGCTCGCCGACCGGATCGGGCGCAA
GCGCGTGCTGATCGTATCGGTGTGCACGTTCGGCTTGCTGTCGATCGCCACCGCGCAGGCGTCGAGTTTCGCGATGCTCG
TCGTCGTGCGCGTGCTCACGGGTGTCGGGCTCGGCGGCGCGATGCCGAACCTGATCGCGCTGTCGTCGGAGGCAGTCGAG
CCGAGGCTGCGCGGCAGCGCGGTCAGCGCGATGTATTGCGGAATCCCGTTCGGCGGCGTGATCGCATCGGCAATCGGCGT
GCTGCTCGTGGGCGACGCGCAGTGGCGGCACATCTTCTACGTCGGCGGGCTCGGGCCGTTGCTGCTCGTGCCGCTGCTCG
CGCGCTGCCTGCCGGAGTCGCGCGCGTACCTCGACGCCGCGCGCATGGGCGGCGCGCGGCCCGCCGCGCGCGCGGCGCTC
TTCGGCGGCGGCCGCGCCTGCGCAACGCTTGCGCTTTGGGTCAGCTACTTCTGCACGCTGATCGTCCTGTATTTCCTGCT
GAACTGGCTGCCGTCGCTGATGGCCGCGCGCGGGCTCGGCCGCGCGGCGGTCGGCGCCGTGCAGATCGGCTTCAACGTCG
GCGGCGGGCTCGGCGCGCTCGGCATCGGGATGCTGAGCGACCGGCTCGGCGCGTCGCGCGTCGTCGGCGCGATGTACGCG
GGCATCGTCGCGTCGCTTGTCGCGCTCGCGCTGGCGCCGGGTTTCGCGGGGCTCGCGGCCGCCGCGTTCGCGGCCGGCAT
GTTCGTGATCGGCGGGCAATCGGTGCTCTATGCGCTCGCCGCGAGCCATTACCCGGCGGCGATGCGCGGCACGGGCGTCG
GCGCGGCGGTCGCGGCCGGGCGGATCGGCTCGGTCGTCGGGCCGCTCGCCGCCGCGCAACTGCTCGCGATGGGGCGCAGC
GGGGCCGTCGTGATCGGCGCGAGCATCCCGGTCACGCTGCTCGCCGCGGCTGCCGCGCTGCTGCTCGTGCGCCGGCCGCC
CACGGCGGACTGA

Upstream 100 bases:

>100_bases
CATTCGCGCACCCCGCTATCGACGCATCGAGGTATCGAAGCATCGCGCATGCCGGTTCCCGCTTGCCCGGCCTGCGCGCT
AAAAATCAGGTTTCCTGATA

Downstream 100 bases:

>100_bases
GCGGGGCGCGGGATCGGCGGGCTGCGGAATTGCGGAACCGTTGAGCTGTCGAGCGACGGAACTGCGGAACTGCGGAACTG
CGGAACTGCGGAACTGCGGA

Product: putative 3-hydroxyphenylpropionic transporter MhpT

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MRQAKQNDIDNDRIAAGSRRRERGRSGDEMDITVTEKRGVATTLALCFAIALLEGLDLQSVGVAAPRMAREFGLSVAQMG
WAFGAGTFGLLPGALLGGRLADRIGRKRVLIVSVCTFGLLSIATAQASSFAMLVVVRVLTGVGLGGAMPNLIALSSEAVE
PRLRGSAVSAMYCGIPFGGVIASAIGVLLVGDAQWRHIFYVGGLGPLLLVPLLARCLPESRAYLDAARMGGARPAARAAL
FGGGRACATLALWVSYFCTLIVLYFLLNWLPSLMAARGLGRAAVGAVQIGFNVGGGLGALGIGMLSDRLGASRVVGAMYA
GIVASLVALALAPGFAGLAAAAFAAGMFVIGGQSVLYALAASHYPAAMRGTGVGAAVAAGRIGSVVGPLAAAQLLAMGRS
GAVVIGASIPVTLLAAAAALLLVRRPPTAD

Sequences:

>Translated_430_residues
MRQAKQNDIDNDRIAAGSRRRERGRSGDEMDITVTEKRGVATTLALCFAIALLEGLDLQSVGVAAPRMAREFGLSVAQMG
WAFGAGTFGLLPGALLGGRLADRIGRKRVLIVSVCTFGLLSIATAQASSFAMLVVVRVLTGVGLGGAMPNLIALSSEAVE
PRLRGSAVSAMYCGIPFGGVIASAIGVLLVGDAQWRHIFYVGGLGPLLLVPLLARCLPESRAYLDAARMGGARPAARAAL
FGGGRACATLALWVSYFCTLIVLYFLLNWLPSLMAARGLGRAAVGAVQIGFNVGGGLGALGIGMLSDRLGASRVVGAMYA
GIVASLVALALAPGFAGLAAAAFAAGMFVIGGQSVLYALAASHYPAAMRGTGVGAAVAAGRIGSVVGPLAAAQLLAMGRS
GAVVIGASIPVTLLAAAAALLLVRRPPTAD
>Mature_430_residues
MRQAKQNDIDNDRIAAGSRRRERGRSGDEMDITVTEKRGVATTLALCFAIALLEGLDLQSVGVAAPRMAREFGLSVAQMG
WAFGAGTFGLLPGALLGGRLADRIGRKRVLIVSVCTFGLLSIATAQASSFAMLVVVRVLTGVGLGGAMPNLIALSSEAVE
PRLRGSAVSAMYCGIPFGGVIASAIGVLLVGDAQWRHIFYVGGLGPLLLVPLLARCLPESRAYLDAARMGGARPAARAAL
FGGGRACATLALWVSYFCTLIVLYFLLNWLPSLMAARGLGRAAVGAVQIGFNVGGGLGALGIGMLSDRLGASRVVGAMYA
GIVASLVALALAPGFAGLAAAAFAAGMFVIGGQSVLYALAASHYPAAMRGTGVGAAVAAGRIGSVVGPLAAAQLLAMGRS
GAVVIGASIPVTLLAAAAALLLVRRPPTAD

Specific function: Could be a transporter for 3-phenylpropionate (hydrocinnamic acid) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=263, Percent_Identity=27.7566539923954, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081723, Length=392, Percent_Identity=49.234693877551, Blast_Score=315, Evalue=5e-87,
Organism=Escherichia coli, GI1786229, Length=388, Percent_Identity=26.2886597938144, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082404, Length=338, Percent_Identity=22.7810650887574, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789152, Length=310, Percent_Identity=24.1935483870968, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082231, Length=174, Percent_Identity=25.2873563218391, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321663, Length=149, Percent_Identity=30.8724832214765, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640198, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640196, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640200, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43498; Mature: 43498

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQAKQNDIDNDRIAAGSRRRERGRSGDEMDITVTEKRGVATTLALCFAIALLEGLDLQS
CCCCCCCCCCCCHHCCCCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
VGVAAPRMAREFGLSVAQMGWAFGAGTFGLLPGALLGGRLADRIGRKRVLIVSVCTFGLL
CCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
SIATAQASSFAMLVVVRVLTGVGLGGAMPNLIALSSEAVEPRLRGSAVSAMYCGIPFGGV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHCHHHCCCHHHHHCCCCCHHHH
IASAIGVLLVGDAQWRHIFYVGGLGPLLLVPLLARCLPESRAYLDAARMGGARPAARAAL
HHHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHH
FGGGRACATLALWVSYFCTLIVLYFLLNWLPSLMAARGLGRAAVGAVQIGFNVGGGLGAL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECCCCCCCHHHH
GIGMLSDRLGASRVVGAMYAGIVASLVALALAPGFAGLAAAAFAAGMFVIGGQSVLYALA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCHHHHHHHH
ASHYPAAMRGTGVGAAVAAGRIGSVVGPLAAAQLLAMGRSGAVVIGASIPVTLLAAAAAL
HHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHH
LLVRRPPTAD
HHHCCCCCCC
>Mature Secondary Structure
MRQAKQNDIDNDRIAAGSRRRERGRSGDEMDITVTEKRGVATTLALCFAIALLEGLDLQS
CCCCCCCCCCCCHHCCCCHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
VGVAAPRMAREFGLSVAQMGWAFGAGTFGLLPGALLGGRLADRIGRKRVLIVSVCTFGLL
CCCCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHH
SIATAQASSFAMLVVVRVLTGVGLGGAMPNLIALSSEAVEPRLRGSAVSAMYCGIPFGGV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHCHHHCCCHHHHHCCCCCHHHH
IASAIGVLLVGDAQWRHIFYVGGLGPLLLVPLLARCLPESRAYLDAARMGGARPAARAAL
HHHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHH
FGGGRACATLALWVSYFCTLIVLYFLLNWLPSLMAARGLGRAAVGAVQIGFNVGGGLGAL
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEEEECCCCCCCHHHH
GIGMLSDRLGASRVVGAMYAGIVASLVALALAPGFAGLAAAAFAAGMFVIGGQSVLYALA
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCHHHHHHHH
ASHYPAAMRGTGVGAAVAAGRIGSVVGPLAAAQLLAMGRSGAVVIGASIPVTLLAAAAAL
HHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHH
LLVRRPPTAD
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]