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The map label for this gene is crp [C]

Identifier: 126447544

GI number: 126447544

Start: 1433525

End: 1434379

Strand: Direct

Name: crp [C]

Synonym: BMA10247_A1475

Alternate gene names: 126447544

Gene position: 1433525-1434379 (Clockwise)

Preceding gene: 126447329

Following gene: 126445739

Centisome position: 60.93

GC content: 70.76

Gene sequence:

>855_bases
GTGATGACCGACGACGTCCAAGCCCCGCACCGCCCGCCGCTCGCCGCGGATGAAGCGGCCCGCGCCGACGAGGCTGCCGC
AGAGCCTGCCTCGGCGCCGGCCGAAGCGCCCGTCGAAACATCAGCCGCCGCGCCCGTGCGAGCGGCGGCCGCGGCGGCCG
CGGCGGCCGGCGCGGGCGAGCTGCGCGCGCTGTTCTCCCGCTGCGGCTGGTTCAACACGCTCGCGCCCGAGCATCAGGCG
CTCGTCGTCGCGCAGTCGCACGCCGAGTACCGCGACGCGGGCGACTGGGTCGCGCGCCGGCAGGCGCCTTCCGAATACTG
GATCGGCGTGCACCGCGGGCTCGTGAAGCTCGCGATCTACAACGCGTCCGGGCGCGGCTGCACGTTCTCCGGCGTGCCGT
CGGGCGGCTGGTTCGGCGAAGGCAGCGTGATCAAGCGCGAGCTGCGCAAGTACGACGTGATCGCGATCCAGCGCTCGCTC
GTGCTGTTCGTGCCGAGCGCGACGTTCCACGCGCTCCTCGACAGCAACCTGCCGTTCACGGGCTTCGTGATCCGCCAGTT
GAACAACCGGATGGGCGAATTCATCGCGTCGATCCAGAACAGCCGGCTGCTCGACGTGAACGCGCGCGTCGCGCAGTCGC
TCGCCCAGCTGTTCAACCCGGACCTGTATCCGGACACCGGCGCGACGCTCGCGATCTCGCAGGAGGAGCTCGGGATGCTG
GTCGGCGTGTCGCGGCAGCGAATCAATCAGGCGCTTCAGCATCTCGAGCGGCTCGGCGCGGTGCGGCTCGCGTACAACCA
GATCGACGTGCTCGATCTGCCGAAGCTCGCGGCGTTCGGGATGGAGCAGATCTGA

Upstream 100 bases:

>100_bases
ATTGGACAAGCCTACTCGCGGCCATTGTGAGCCGTCTGTCATGCAAGCGACAGACTCGCCGGCCACGACCGCGCGTATTC
CCTATCCTCGCAAACCCTGT

Downstream 100 bases:

>100_bases
CGGCCCGGTTGGCGACCGCGGCCGCCATCGCGTTCGCCGTCCATGATGCCGACCGGTCGCGGCCACGCGCGGCCTGCGCT
GTCGCCGCCGCCGTCCGCTC

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Regulatory Protein; Transcription Regulator Protein; Cyclic-Nucleotide-Gated Cation Channel; CNMP Regulatory Protein; HTH Crp Family Transcriptional Regulator; CAMP-Dependent Transcriptional Regulator; Transcriptional Regulator Crp; Transcriptional Regulator Crp Family

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAAAAAAAAAGAGELRALFSRCGWFNTLAPEHQA
LVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSL
VLFVPSATFHALLDSNLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGML
VGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI

Sequences:

>Translated_284_residues
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAAAAAAAAAGAGELRALFSRCGWFNTLAPEHQA
LVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSL
VLFVPSATFHALLDSNLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGML
VGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
>Mature_284_residues
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAAAAAAAAAGAGELRALFSRCGWFNTLAPEHQA
LVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSL
VLFVPSATFHALLDSNLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGML
VGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30527; Mature: 30527

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAAAAAAAAAGAGE
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
LRALFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIY
HHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEE
NASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSATFHALLDSNLPFT
CCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEECCHHHHHHHCCCCCHH
GFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGML
HHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHH
VGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAAAAAAAAAGAGE
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
LRALFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIY
HHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEE
NASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSATFHALLDSNLPFT
CCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEECCHHHHHHHCCCCCHH
GFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGML
HHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHH
VGVSRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA