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The map label for this gene is glcD [H]

Identifier: 126447290

GI number: 126447290

Start: 1344358

End: 1345851

Strand: Reverse

Name: glcD [H]

Synonym: BMA10247_A1377

Alternate gene names: 126447290

Gene position: 1345851-1344358 (Counterclockwise)

Preceding gene: 126445787

Following gene: 126445649

Centisome position: 57.2

GC content: 72.22

Gene sequence:

>1494_bases
ATGCGCGAAGTGACCGACGACGGACAGCAGTGGGACGGGCGGGCGGCGGCTTTCGCGGGCGTGCCGCCCGGCGGCGGCGC
GCCTGCCGCGTTCGCCACGCCGCAGACGATCGGGCGCTGCGTCGAGGCGTTGCGCGCGATCGTCGGCGAGCGCCTCGCAG
TCGGGCGCGCGGTGCGCGAGCAGCACGGCAAGGACATCTCGTTCCATCCGGGCGCGCCGCCCGACGCCGTCGCGTTCGTG
CGGACGACGGCCGAGGTCGCCGAGATCACACGCGCATGCCATCGGCTGCGCGTGCCGCTGATTCCGTTCGGCACCGGCAC
GTCGTGCGAGGGGCACATCGCCGCGCTGCGCGGCGGCGTATGCATCGATCTGTCCGGCATGAACCGGATTCTGCGCGTGA
GCGCCGAGGATCTCGACTGCACGGTCGAGGCGGGGGTGACGCGCAAGCAGCTCAATGCGCACCTGCGCGACACGGGGCTC
TTCTTTCCGATCGACCCGGGCGCGGACGCGTCGATCGGCGGCATGTGCTCGACGCGCGCGTCCGGCACGAACGCGGTGCG
CTACGGGACGATGCGCGAGAGCGTGCTCGCGCTCGAAGTCGTGCTGCCGAACGGCGACGTCGTCTCGGTCGGCTCGCGTG
CGCGCAAGTCGGCGGCGGGCTACGATCTCGCGCGCCTGTTCGTCGGCGCGGAAGGCACGCTCGGCACGATCACGGGCGTC
ACGCTGCGGCTGCATCCGCGCCCGGACCGGCTATCCGCCGCGGTGTGCGGTTTCCCGGACCTGAAGGCCGCGGTCGACTC
GGTGATCGGCGTCATCCGCAGCGGCGTGCCGATCGCGCGCGTCGAGTTGCTCGACGCACTGCAGATCGTCGCGTGCAACC
GCTATGCGAAGCTGAGCCTCGACGAGCGGCCGACGCTCTTTTTCGAGTTCGCGGGGTTCGGCGCGGCCGTCGACGAGCAG
ATCGACTGGGTCGGGGAGATTTGCGCGGGCTACGGCGGCGGTGAATTCCGCTGGGCGTCGCGCCCGGAGGAGCGCAGCGC
GCTGTGGGCGGCGCGGCACGACGCGTGGTGGGCGGCGCTCGCGCTGCGGCCCGGCTGCGAGGGGATGCCGACCGATTCGT
GCGTGCCCGTGTCGCGGCTCGCGGAGGCGGTGCTCGCCGCGCGCGCGGACGTGGACGCGCTCGGCCTCGTCGCGACGATC
TGCGGGCACGTCGGCGACGGCAACTTTCACGTATGCATCGCGATCGATCCGGCCGACCCGGACGAACTCGCGCGCGCAAC
CGAGCTGAACCGGCGGCTCGCGCTGCGCGCGATCGCGTTGGGCGGCACCTGCACGGGCGAGCACGGCGTCGGTTACGGGA
AGATCGGCTACCTGGAGCGCGAGCATCCGACGGCGCTGCAATTGATGGCGGCCGTCAAGCGCGCGCTCGATCCGCGCGGC
ATCATGAATCCGGGCAAGGTGCTGCATCACGACCGGTATCCGCCGTTCGACTGA

Upstream 100 bases:

>100_bases
GCGCGGGGCGCGCGCGGCGGCGCGGGGATGGGGGCGGCCCCGCGTGTGCGCGGGCTGCGCGCCGCGGCGAGCGGGCGCGA
TCGACGAACGGAGGCGACGC

Downstream 100 bases:

>100_bases
GTTCTGGACGGCGCGCGGGCGGGGCGAGCGGCCGATCCGGCCGTGCGCGGCCCGGCCCGGCGGGCCGGCCGACGAACGGA
CGCGGCGCGGCGTGCGTCGC

Product: putative glycolate oxidase, subunit GlcD

Products: pyruvate; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MREVTDDGQQWDGRAAAFAGVPPGGGAPAAFATPQTIGRCVEALRAIVGERLAVGRAVREQHGKDISFHPGAPPDAVAFV
RTTAEVAEITRACHRLRVPLIPFGTGTSCEGHIAALRGGVCIDLSGMNRILRVSAEDLDCTVEAGVTRKQLNAHLRDTGL
FFPIDPGADASIGGMCSTRASGTNAVRYGTMRESVLALEVVLPNGDVVSVGSRARKSAAGYDLARLFVGAEGTLGTITGV
TLRLHPRPDRLSAAVCGFPDLKAAVDSVIGVIRSGVPIARVELLDALQIVACNRYAKLSLDERPTLFFEFAGFGAAVDEQ
IDWVGEICAGYGGGEFRWASRPEERSALWAARHDAWWAALALRPGCEGMPTDSCVPVSRLAEAVLAARADVDALGLVATI
CGHVGDGNFHVCIAIDPADPDELARATELNRRLALRAIALGGTCTGEHGVGYGKIGYLEREHPTALQLMAAVKRALDPRG
IMNPGKVLHHDRYPPFD

Sequences:

>Translated_497_residues
MREVTDDGQQWDGRAAAFAGVPPGGGAPAAFATPQTIGRCVEALRAIVGERLAVGRAVREQHGKDISFHPGAPPDAVAFV
RTTAEVAEITRACHRLRVPLIPFGTGTSCEGHIAALRGGVCIDLSGMNRILRVSAEDLDCTVEAGVTRKQLNAHLRDTGL
FFPIDPGADASIGGMCSTRASGTNAVRYGTMRESVLALEVVLPNGDVVSVGSRARKSAAGYDLARLFVGAEGTLGTITGV
TLRLHPRPDRLSAAVCGFPDLKAAVDSVIGVIRSGVPIARVELLDALQIVACNRYAKLSLDERPTLFFEFAGFGAAVDEQ
IDWVGEICAGYGGGEFRWASRPEERSALWAARHDAWWAALALRPGCEGMPTDSCVPVSRLAEAVLAARADVDALGLVATI
CGHVGDGNFHVCIAIDPADPDELARATELNRRLALRAIALGGTCTGEHGVGYGKIGYLEREHPTALQLMAAVKRALDPRG
IMNPGKVLHHDRYPPFD
>Mature_497_residues
MREVTDDGQQWDGRAAAFAGVPPGGGAPAAFATPQTIGRCVEALRAIVGERLAVGRAVREQHGKDISFHPGAPPDAVAFV
RTTAEVAEITRACHRLRVPLIPFGTGTSCEGHIAALRGGVCIDLSGMNRILRVSAEDLDCTVEAGVTRKQLNAHLRDTGL
FFPIDPGADASIGGMCSTRASGTNAVRYGTMRESVLALEVVLPNGDVVSVGSRARKSAAGYDLARLFVGAEGTLGTITGV
TLRLHPRPDRLSAAVCGFPDLKAAVDSVIGVIRSGVPIARVELLDALQIVACNRYAKLSLDERPTLFFEFAGFGAAVDEQ
IDWVGEICAGYGGGEFRWASRPEERSALWAARHDAWWAALALRPGCEGMPTDSCVPVSRLAEAVLAARADVDALGLVATI
CGHVGDGNFHVCIAIDPADPDELARATELNRRLALRAIALGGTCTGEHGVGYGKIGYLEREHPTALQLMAAVKRALDPRG
IMNPGKVLHHDRYPPFD

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=453, Percent_Identity=53.8631346578366, Blast_Score=490, Evalue=1e-138,
Organism=Homo sapiens, GI37595754, Length=476, Percent_Identity=51.2605042016807, Blast_Score=481, Evalue=1e-136,
Organism=Homo sapiens, GI119964728, Length=421, Percent_Identity=31.353919239905, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4501993, Length=222, Percent_Identity=28.8288288288288, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1789351, Length=419, Percent_Identity=31.2649164677804, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI1787977, Length=498, Percent_Identity=27.5100401606426, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI48994907, Length=438, Percent_Identity=24.4292237442922, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI48994914, Length=192, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71992373, Length=461, Percent_Identity=45.9869848156182, Blast_Score=406, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71992381, Length=461, Percent_Identity=44.6854663774403, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71992392, Length=378, Percent_Identity=47.8835978835979, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17534361, Length=453, Percent_Identity=26.4900662251656, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17556096, Length=457, Percent_Identity=22.7571115973742, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320027, Length=491, Percent_Identity=37.2708757637475, Blast_Score=303, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6320764, Length=433, Percent_Identity=27.2517321016166, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320023, Length=489, Percent_Identity=25.5623721881391, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18921117, Length=429, Percent_Identity=28.6713286713287, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24639277, Length=429, Percent_Identity=28.6713286713287, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24639275, Length=429, Percent_Identity=28.6713286713287, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24653753, Length=459, Percent_Identity=27.4509803921569, Blast_Score=119, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.2.4

Molecular weight: Translated: 52556; Mature: 52556

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVTDDGQQWDGRAAAFAGVPPGGGAPAAFATPQTIGRCVEALRAIVGERLAVGRAVRE
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHGKDISFHPGAPPDAVAFVRTTAEVAEITRACHRLRVPLIPFGTGTSCEGHIAALRGGV
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHEECCCE
CIDLSGMNRILRVSAEDLDCTVEAGVTRKQLNAHLRDTGLFFPIDPGADASIGGMCSTRA
EEEECCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCC
SGTNAVRYGTMRESVLALEVVLPNGDVVSVGSRARKSAAGYDLARLFVGAEGTLGTITGV
CCCCEEEECCHHHCEEEEEEEECCCCEEECCHHHHHHHCCCCEEHHEECCCCCCEEEEEE
TLRLHPRPDRLSAAVCGFPDLKAAVDSVIGVIRSGVPIARVELLDALQIVACNRYAKLSL
EEEECCCCCHHCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEECC
DERPTLFFEFAGFGAAVDEQIDWVGEICAGYGGGEFRWASRPEERSALWAARHDAWWAAL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCEEEEE
ALRPGCEGMPTDSCVPVSRLAEAVLAARADVDALGLVATICGHVGDGNFHVCIAIDPADP
EECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCH
DELARATELNRRLALRAIALGGTCTGEHGVGYGKIGYLEREHPTALQLMAAVKRALDPRG
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCC
IMNPGKVLHHDRYPPFD
CCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MREVTDDGQQWDGRAAAFAGVPPGGGAPAAFATPQTIGRCVEALRAIVGERLAVGRAVRE
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QHGKDISFHPGAPPDAVAFVRTTAEVAEITRACHRLRVPLIPFGTGTSCEGHIAALRGGV
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHEECCCE
CIDLSGMNRILRVSAEDLDCTVEAGVTRKQLNAHLRDTGLFFPIDPGADASIGGMCSTRA
EEEECCCCEEEEEECCCCCEEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCC
SGTNAVRYGTMRESVLALEVVLPNGDVVSVGSRARKSAAGYDLARLFVGAEGTLGTITGV
CCCCEEEECCHHHCEEEEEEEECCCCEEECCHHHHHHHCCCCEEHHEECCCCCCEEEEEE
TLRLHPRPDRLSAAVCGFPDLKAAVDSVIGVIRSGVPIARVELLDALQIVACNRYAKLSL
EEEECCCCCHHCEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEECC
DERPTLFFEFAGFGAAVDEQIDWVGEICAGYGGGEFRWASRPEERSALWAARHDAWWAAL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCEEEEE
ALRPGCEGMPTDSCVPVSRLAEAVLAARADVDALGLVATICGHVGDGNFHVCIAIDPADP
EECCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCH
DELARATELNRRLALRAIALGGTCTGEHGVGYGKIGYLEREHPTALQLMAAVKRALDPRG
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCC
IMNPGKVLHHDRYPPFD
CCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-lactate; ferricytochrome c

Specific reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]