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The map label for this gene is glsA [H]

Identifier: 126447110

GI number: 126447110

Start: 1531673

End: 1532587

Strand: Direct

Name: glsA [H]

Synonym: BMA10247_A1594

Alternate gene names: 126447110

Gene position: 1531673-1532587 (Clockwise)

Preceding gene: 126447853

Following gene: 126446370

Centisome position: 65.1

GC content: 66.78

Gene sequence:

>915_bases
ATGGATTATCAGCCGATTCTCGAACGCATCCACACCGAACTCGCGCCCTGGATCGGCGCGGGCCGCGTCGCCGACTACAT
CCCCGAACTCGCGAAAGTGCCGGCCGAGCGGTTCGGCATGGCCGTCGTCACGCTCGACGGCCGCATCCACACGGTCGGCG
ACGCGCGCGAACGCTTCTCGATCCAGAGCATCTCGAAGCTGTTCGCGTGCACGCTCGCGTTCCAGTTGCTCGGCGATGCG
CTGTGGGAACGAGTCGGCCGAGAGCCGTCGGGCAACGCGTTCAACTCGCTCGTTCAGCTCGAAAGCGAGCGCGGCATACC
GCGCAATCCGTTCATCAATGCGGGGGCGCTGATCGTCACCGACGTCCTGTGCCGCCGCTTCGTCGGCGCCGAGACGGCGC
TCGTCCAGTTCATGCGCCGTCTGACAGGCGTCGCCGAGCTCGACTACGATCTGCGCGTCGCGAGCTCCGAGCTCGCCCAT
GCCGAACGCAATCGCGCGATGGCGCACTTCATGGCGAGCTTCGGCAATCTGCACATGCCGCCCGAGACGGTGATCGACGC
CTATTGCCGCCAGTGTGCGATCGAGATGAACTGCATCGAGCTGGCGACCGCGGCGCTCTTTCTCGCCAACGCGGGCGTTG
CGCCCGTATCCGGCGAACGCATTCTCGATGCCAGCTCGGCCAAGCGCCTGTCCGCCCTCATGCTGACATGCGGCACGTAC
GACGCGGCAGGCGATTTCGTGTATCGCGTCGGCCTGCCCGCGAAAAGCGGCGTGGGCGGCGGCATCGTCGCCGTGCTGCC
GGGCGAGATGGCCGTGTGCGTCTGGTCGCCCGGGCTCGACGCAAACGGCAACTCCGTCGCCGGCGTTCAGGCGCTCGAAC
AGTTGACCACGCTGACCGGCCGGTCGATTTTCTGA

Upstream 100 bases:

>100_bases
GCCACCGTAGCGGCAGCAAGCCGATGCTTGACGAATCGCCGCCGAGAAGGTTCCATACGGGCTCGCTTCACACCCGCGCG
GCGCAGCGCGCATCGATTCA

Downstream 100 bases:

>100_bases
TCGCCGGCATCGCACGCGATCGCCGGTTTGTTTTCGCGCGCGGGCACGCCGGCGCCGCAATGGCTGTCGATCCGTTCGGG
GCGCTCGCGCGGATGAAGCG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MDYQPILERIHTELAPWIGAGRVADYIPELAKVPAERFGMAVVTLDGRIHTVGDARERFSIQSISKLFACTLAFQLLGDA
LWERVGREPSGNAFNSLVQLESERGIPRNPFINAGALIVTDVLCRRFVGAETALVQFMRRLTGVAELDYDLRVASSELAH
AERNRAMAHFMASFGNLHMPPETVIDAYCRQCAIEMNCIELATAALFLANAGVAPVSGERILDASSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSVAGVQALEQLTTLTGRSIF

Sequences:

>Translated_304_residues
MDYQPILERIHTELAPWIGAGRVADYIPELAKVPAERFGMAVVTLDGRIHTVGDARERFSIQSISKLFACTLAFQLLGDA
LWERVGREPSGNAFNSLVQLESERGIPRNPFINAGALIVTDVLCRRFVGAETALVQFMRRLTGVAELDYDLRVASSELAH
AERNRAMAHFMASFGNLHMPPETVIDAYCRQCAIEMNCIELATAALFLANAGVAPVSGERILDASSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSVAGVQALEQLTTLTGRSIF
>Mature_304_residues
MDYQPILERIHTELAPWIGAGRVADYIPELAKVPAERFGMAVVTLDGRIHTVGDARERFSIQSISKLFACTLAFQLLGDA
LWERVGREPSGNAFNSLVQLESERGIPRNPFINAGALIVTDVLCRRFVGAETALVQFMRRLTGVAELDYDLRVASSELAH
AERNRAMAHFMASFGNLHMPPETVIDAYCRQCAIEMNCIELATAALFLANAGVAPVSGERILDASSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSVAGVQALEQLTTLTGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=293, Percent_Identity=37.542662116041, Blast_Score=195, Evalue=3e-50,
Organism=Homo sapiens, GI20336214, Length=300, Percent_Identity=34, Blast_Score=174, Evalue=9e-44,
Organism=Escherichia coli, GI1787804, Length=300, Percent_Identity=52.3333333333333, Blast_Score=317, Evalue=5e-88,
Organism=Escherichia coli, GI1786693, Length=307, Percent_Identity=37.785016286645, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17507019, Length=284, Percent_Identity=38.0281690140845, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17532727, Length=289, Percent_Identity=36.3321799307958, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI193204073, Length=287, Percent_Identity=36.2369337979094, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI193204075, Length=289, Percent_Identity=35.9861591695502, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24653162, Length=290, Percent_Identity=36.551724137931, Blast_Score=187, Evalue=9e-48,
Organism=Drosophila melanogaster, GI281363241, Length=290, Percent_Identity=36.551724137931, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363239, Length=290, Percent_Identity=36.551724137931, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653164, Length=289, Percent_Identity=35.6401384083045, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653158, Length=289, Percent_Identity=35.6401384083045, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653166, Length=289, Percent_Identity=35.6401384083045, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653156, Length=290, Percent_Identity=36.551724137931, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI116008307, Length=289, Percent_Identity=35.6401384083045, Blast_Score=186, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32645; Mature: 32645

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYQPILERIHTELAPWIGAGRVADYIPELAKVPAERFGMAVVTLDGRIHTVGDARERFS
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCEEEEEECCEEEECCCHHHHHH
IQSISKLFACTLAFQLLGDALWERVGREPSGNAFNSLVQLESERGIPRNPFINAGALIVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLCRRFVGAETALVQFMRRLTGVAELDYDLRVASSELAHAERNRAMAHFMASFGNLHMP
HHHHHHHHCCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PETVIDAYCRQCAIEMNCIELATAALFLANAGVAPVSGERILDASSAKRLSALMLTCGTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCC
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSVAGVQALEQLTTLTG
CCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
RSIF
CCCC
>Mature Secondary Structure
MDYQPILERIHTELAPWIGAGRVADYIPELAKVPAERFGMAVVTLDGRIHTVGDARERFS
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCEEEEEECCEEEECCCHHHHHH
IQSISKLFACTLAFQLLGDALWERVGREPSGNAFNSLVQLESERGIPRNPFINAGALIVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLCRRFVGAETALVQFMRRLTGVAELDYDLRVASSELAHAERNRAMAHFMASFGNLHMP
HHHHHHHHCCHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PETVIDAYCRQCAIEMNCIELATAALFLANAGVAPVSGERILDASSAKRLSALMLTCGTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHCCC
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSVAGVQALEQLTTLTG
CCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
RSIF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA